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W296600

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Ogbole Omonike Oluyemisi et al.
Pharmaceutical biology, 53(6), 882-887 (2014-11-29)
Plants of the Zephyranthes genus are globally used in folk medicine. In a previous study, Zephyranthes candida Linn. (Amaryllidaceae) was identified as having antiviral properties; this led to anti-poliovirus assay-guided isolation of compounds from crude methanol extract of the plant....
Shaofu Yu et al.
Natural product research, 29(14), 1336-1341 (2015-02-07)
Two new quercetin glycoside derivatives named quercetin-3-O-[2-O-trans-caffeoyl-α-L-rhamnopyranosyl-(1 → 6)-β-D-glucopyranoside] (1) and quercetin-3-O-[2-O-trans-caffeoyl-β-L-rhamnopyranosyl-(1 → 6)-β-D-glucopyranoside] (2) along with three known flavonoids, 5-hydroxy-6,7,3',4',5'-pentamethoxyflavone (3), 5,7-dihydroxy-8-methoxyflavone (4) and kaempferol 3-O-β-D-glucopyranoside (5), were isolated from the fruits of Gardenia jasminoides var. radicans. The structures...
Akio Ebihara et al.
Extremophiles : life under extreme conditions, 19(4), 775-785 (2015-05-23)
Hydrogen peroxide (H2O2) produces hydroxyl radicals that directly attack a variety of biomolecules and cause severe cellular dysfunction. An extremely thermophilic bacterium, Thermus thermophilus HB8, possesses at least three enzymes that can scavenge H2O2: manganese-containing catalase (TTHA0122, MnCAT), a possible...
E Mázl Chánová et al.
Physiological research, 64 Suppl 1, S61-S73 (2015-10-09)
In this study, we investigate the preparation of surface pattern of functional groups on poly(lactide) (PLA) surfaces through the controlled deposition of core-shell self-assemblies based on functionalized PLA-b-PEO amphiphilic block copolymers from selective solvents. Through grafting RGDS peptide onto the...
Pyridine.
IARC monographs on the evaluation of carcinogenic risks to humans, 77, 503-528 (2000-12-02)
Lu Yangfang et al.
Electrophoresis, 36(17), 2120-2127 (2015-05-21)
Submicron, non-porous, chiral silica stationary phase has been prepared by the immobilization of functionalized β-CD derivatives to isocyanate-modified silica via chemical reaction and applied to the pressurized capillary electrochromatography (pCEC) enantio-separation of various chiral compounds. The submicron, non-porous, cyclodextrin-based chiral...
Ursula J Williams et al.
Dalton transactions (Cambridge, England : 2003), 43(43), 16197-16206 (2014-08-26)
The trivalent compound K[Ce[N(SiHMe2)2]4] was synthesized and oxidized, providing a convenient route to the reported cerium(IV) compound Ce[N(SiHMe2)2]4. Protonolysis reactions of Ce[N(SiHMe2)2]4 with tert-butanol, substituted benzyl alcohols, and 2,6-diphenylphenol yielded the neutral tetravalent compounds Ce(O(t)Bu)4(py)2, Ce2(OCH2C6R5)8(thf)2 (R = Me, F)...
Frida Torell et al.
PloS one, 10(6), e0129260-e0129260 (2015-06-19)
Hierarchical modelling was applied in order to identify the organs that contribute to the levels of metabolites in plasma. Plasma and organ samples from gut, kidney, liver, muscle and pancreas were obtained from mice. The samples were analysed using gas...
Veronika Sele et al.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 30, 171-179 (2015-01-27)
In the present study liver samples (n=26) of Northeast Arctic cod (Gadus morhua), ranging in total arsenic concentrations from 2.1 to 240mg/kg liver wet weight (ww), were analysed for their content of total arsenic and arsenic species in the lipid-soluble...
Jaroslav Zelenka et al.
Oxidative medicine and cellular longevity, 2015, 351698-351698 (2015-07-15)
A moderate elevation of reactive oxygen species (ROS) production and a mild inhibition of mitochondrial respiratory chain have been associated with a health promotion and a lifespan extension in several animal models of aging. Here, we tested whether this phenomenon...
Shigeo Hayashi et al.
Journal of enzyme inhibition and medicinal chemistry, 29(6), 846-867 (2014-02-13)
Because of the pivotal role of cyclooxygenase (COX) in the inflammatory processes, non-steroidal anti-inflammatory drugs (NSAIDs) that suppress COX activities have been used clinically for the treatment of inflammatory diseases/syndromes; however, traditional NSAIDs exhibit serious side-effects such as gastrointestinal damage...
T Shimada et al.
Cancer research, 51(19), 5284-5291 (1991-10-01)
The ability of cigarette smoke condensate to induce a genotoxic response has been measured in liver microsomal and reconstituted monooxygenase systems containing rat and human cytochrome P-450 (P-450) enzymes, as determined by umu gene expression in Salmonella typhimurium TA1535/pSK1002. The...
Kai Cai et al.
Analytica chimica acta, 882, 90-100 (2015-06-05)
A novel derivatization-ultrasonic assisted-dispersive liquid-liquid microextraction (UA-DLLME) method for the simultaneous determination of 11 main carbohydrates in tobacco has been developed. The combined method involves pressurized liquid extraction (PLE), derivatization, and UA-DLLME, followed by the analysis of the main carbohydrates...
Jacky Pouessel et al.
Dalton transactions (Cambridge, England : 2003), 42(14), 4859-4872 (2013-02-02)
The synthesis of a new linear bis-tetraamine ligand L1, based on two 1,4,8,11-tetraazaundecane units grafted at the 2 and 6 positions of a pyridinyl linker substituted by an anthracenyl fluorophore in the para position, is described and anion complexation studies...
Elizabeth Kish et al.
Biochimica et biophysica acta, 1847(10), 1044-1054 (2015-05-25)
Orange carotenoid protein (OCP) is a cyanobacterial photoactive protein which binds echinenone as a chromophore; it is involved in photoprotection of these photosynthetic organisms against intense illumination. In its resting state, OCP appears orange (OCPo), and turns into a red...
N Semmo et al.
Journal of viral hepatitis, 22(7), 617-624 (2014-12-10)
To understand the changes in the metabolome of hepatitis C virus (HCV)-infected persons, we conducted a metabolomic investigation in both plasma and urine of 30 HCV-positive individuals using plasmas from 30 HCV-negative blood donors and urines from 30 healthy volunteers....
Jipan Yu et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 19(13), 4271-4277 (2013-02-13)
Efficient copper-catalyzed aerobic oxidative C-H and C-C functionalization of 1-[2-(arylamino)aryl]ethanones leading to acridones has been developed. The procedure involves cleavage of aromatic C-H and acetyl C-C bonds with intramolecular formation of a diarylketone bond. The protocol uses inexpensive Cu(O2CCF3)2 as...
V Subbaramaiah et al.
Journal of hazardous materials, 248-249, 355-363 (2013-02-19)
Cerium supported SBA-15 (Ce/SBA-15) was synthesized by two-step synthesis method in acidic medium. It was further characterized by various characterization techniques such as X-ray diffraction, field-emission scanning electron microscopy, Fourier transform infrared spectroscopy and N2 adsorption-desorption pore size distribution analysis....
Rebeca Y Cabrera-Padilla et al.
Bioprocess and biosystems engineering, 38(5), 805-814 (2014-11-14)
Candida rugosa lipase (CRL) was immobilized on an eco-friendly support poly(3-hydroxybutyrate-co-hydroxyvalerate) (PHBV), by physical adsorption, using different ionic liquids (ILs) as immobilization additives. This was to investigate the influence of cationic core ([C4mpy]Cl, [C4min]Cl), of anions ([C4min]Cl, [C4min]N(CN)2, [C4min]Tf2N), and...
Joanna Kałużna-Czaplińska et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 966, 70-76 (2014-02-26)
There is a need to identify metabolic phenotypes in autism as they might each require unique approaches to prevention. Biological markers can help define autism subtypes and reveal potential therapeutic targets. The aim of the study was to identify alterations...
Makiko Yasuda et al.
Molecular medicine (Cambridge, Mass.), 21, 487-495 (2015-06-11)
Acute intermittent porphyria (AIP) is an autosomal-dominant hepatic disorder caused by the half-normal activity of hydroxymethylbilane (HMB) synthase. Symptomatic individuals experience life-threatening acute neurovisceral attacks that are precipitated by factors that induce the hepatic expression of 5-aminolevulinic acid synthase 1...
Samuel Eyley et al.
Nanoscale, 7(34), 14413-14421 (2015-08-08)
Cellulose nanocrystals were grafted with imidazole functionalities up to DS 0.06 using a one-pot functionalization strategy. The resulting nanocrystals were shown to have a pH responsive surface charge which was found to be positive below pH 6 and negative above...
Ping Yang et al.
Journal of Asian natural products research, 17(8), 800-807 (2015-01-30)
Two new triterpenoid saponins, oleiferoside N and oleiferoside O, were isolated from the EtOH extract from the roots of Camellia oleifera C. Abel. Their structures were elucidated as 16α-acetoxy-21β,22α-O-diangeloyloxy-23,28-dihydroxyolean-12-ene 3β-O-β-D-xylopyranosyl-(1 → 3)-α-L-arabinopyranosyl-(1 → 3)-β-D-glucuronopyranoside (1), 16α-acetoxy-21β-O-angeloyloxy-23,28-dihydroxy-22α-O-(2-methylbutanoyloxy)olean-12-ene 3β-O-β-D-xylopyranosyl-(1 → 3)-α-L-arabinopyranosyl-(1 →...
Wim Ammerlaan et al.
Biopreservation and biobanking, 12(5), 351-357 (2014-10-08)
Formal validation of methods for biospecimen processing in the context of accreditation in laboratories and biobanks is lacking. A protocol for processing of a biospecimen (urine) was validated for fitness-for-purpose in terms of key downstream endpoints. Urine processing was optimized...
Sabine Kokarnig et al.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 29, 83-90 (2014-07-27)
Selenium metabolic patterns in the human body originating from five distinct selenium dietary sources, selenate, selenite, selenomethionine (SeMet), methylselenocysteine (MeSeCys) and selenized yeast, were investigated by performing concurrent HPLC-mass spectrometric analysis of human serum and urine. Total selenium and selenium...
Saet Buyl Lee et al.
Plant & cell physiology, 56(1), 48-60 (2014-10-13)
The aerial parts of all land plants are covered with hydrophobic cuticular wax layers that act as the first barrier against the environment. The MYB94 transcription factor gene is expressed in abundance in aerial organs and shows a higher expression...
Tiziana Pacchiarotta et al.
The Analyst, 140(8), 2834-2841 (2015-03-03)
Urinary tract infection (UTI) is among the most common bacterial infections worldwide. The understanding of the physiological mechanisms affected by UTI may need modern integrative '-omics' technologies, and metabolomics in particular. Here we present the first GC-APCI-MS-based explorative metabolomics study...
Zehra Bolat et al.
Acta chimica Slovenica, 62(2), 428-436 (2015-06-19)
A novel benzofuran ketoxime derived polymer, poly(benzofuran-2-yl-methylketoxime-O-methacrylate) [poly(BMKMA], was firstly synthesized by free radical polymerization method. Its thermal degradation studies were performed by thermogravimetric analysis (TGA) in order to determine the actual reaction mechanisms of the decomposition process. The activation...
Daniel Sieh et al.
Journal of the American Chemical Society, 135(10), 3971-3982 (2013-02-26)
Si-H activation in triethyl- and triarylsilanes by a square-planar pyridine-diimine iridium complex with a terminal nitrido unit leads to the corresponding silyl amido complexes, which were unambiguously characterized by X-ray crystallography. Based on detailed combined kinetic and theoretical studies (DFT)...
R M Toledano et al.
Journal of chromatography. A, 1370, 171-178 (2014-12-03)
Boldenone (Bo), androsta-1,4-dien-17β-ol-3-one, is an anabolic androgenic steroid not clinically approved for human application. Despite this, many cases are reported every year of athletes testing positive for Bo or its main metabolite 5β-androst-1-en-17β-ol-3-one (BoM). Recently the capability of different human...
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