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HPLC Analysis of Caseins on BIOshell™ A400 Protein C4
-casein basis (electrophoresis), lyophilized powder; β-Casein from bovine milk, BioUltra, ≥98% (PAGE)
Proline Derivatization and Enantioresolution by Chiral GC
Amino acids are building blocks of peptides and proteins. Enantiomeric separation of these molecules can be performed through chromatography by chiral stationary phases. This article describes the chiral GC analysis of one amino acid, proline, after achiral derivatization.
Peptide Impurities
Peptide Impurities
USP HPLC Analysis of L-Methionine on Ascentis® Express OH5
Separation of L-Methionine, Pharmaceutical Secondary Standard; Certified Reference Material
Macmillan Imidazolidinone Organocatalysts
In collaboration with Materia, Inc., we are pleased to offer six imidazolidinone OrganoCatalysts™.
PEPscreen® Peptide Library Frequently Asked Questions (FAQ)
PEPscreen peptides are synthesized on proprietary, state-of-the-art robotic platforms utilizing optimized protocols based on Fmoc-chemistry.
HPLC Analysis of Polyglutamate Metabolites of Methotrexate on TSKgel® NH2-100 and ODS-100V
Separation of Methotrexate (MTX)-PG; Methotrexate (MTX)-PG2; Methotrexate (MTX)-PG3 ; Methotrexate (MTX)-PG4; Methotrexate (MTX)-PG5; Methotrexate (MTX)-PG6; Methotrexate (MTX)-PG7
Rink Amide (RAM) Resins
A broad variety of 4-((2,4-dimethoxyphenyl)(Fmoc-amino)methyl)phenoxyalkyl functionalized supports have been developed for the synthesis of peptide carboxamides.
The Use of Derivatization Reagents for GC
The Use of Derivatization Reagents for GC
A Comparison of Solid Phase Extraction (SPE) Products Used to Purify Peanut Paste Extract for Aflatoxin Analysis
Supel Tox AflaZea SPE produced exceptional analyte recoveries with good reproducibility for all aflatoxins while requiring less than half the sample volume required by competing products.HPLC analysis of all spiked samples after SPE cleanup showed that all compared SPE cartridges...
Developing HPLC Methods
We recommend every HPLC method developer have these four columns in their arsenal; Ascentis C18, Ascentis RP-Amide, Ascentis Phenyl and Discovery HS F5.
Angiotensin Receptors
We offer many products related to angiotensin receptors for your research needs.
Coupling Reagents
In principle, the seemingly simple formation of a peptide bond can be accomplished using all the procedures available in organic chemistry for the synthesis of carboxylic acid amides. However, due to the presence of various functional groups in natural and...
Impact of Mobile Phase Additives on LC-MS Sensitivity, Demonstrated using Spice Cannabinoids
This study demonstrates the impact of various mobile phase modifiers on the separation; formate modifiers outperform acetate in terms of MS signals (or sensitivity) and chromatographic resolution.
How to Maximize Sensitivity in LC-MS
Various measures and options for maximized LC-MS sensitivity and low limit of detection (LOD) are shown on this page. Each and every tip avoids contaminations causing signal suppression, adduct formation, elevated background noise and increased spectrum complexity.
Chiral Chromatography Frequently Asked Questions
Chiral Chromatography Frequently Asked Questions
Starbons: Cooking up Nanostructured Mesoporous Materials
Our strategy is to synthesize mesoporous carbonaceous materials (“Starbons”) using mesoporous expanded starch as the precursor without the need for a templating agent.
Aldehydes - Types & Structure
Technical article regarding Aldehydes - Types & Structure
Monolithic Silica with Bimodal Pore Structure
Monolithic silica HPLC columns enable high-throughput analysis at low back pressure without loss of separation efficiency or peak capacity.
Group 11 Thin Films by Atomic Layer Deposition
In this article, we will discuss coinage metal deposition processes in order to provide a sense of the most critical precursors, reducing agents, and processes.
Thermal Transitions of Homopolymers: Glass Transition & Melting Point
Literature values for the glass transition temperature, (Tg), and melting temperature, (Tm), are given for the more common homopolymers.
GABAC Receptors
Sigma-Aldrich offers many products related to GABAC receptors for your research needs.
Glycine Receptors
The amino acid glycine is a major inhibitory neurotransmitter in the vertebrate CNS. Glycinergic synapses are particularly abundant in spinal cord and brain stem, but are also found in higher brain regions including the hippocampus. The inhibitory actions of glycine...
Synthesis of Melting Gels Using Mono-Substituted and Di-Substituted Alkoxysiloxanes
Synthesis of Melting Gels Using Mono-Substituted and Di-Substituted Alkoxysiloxanes
Heck Reaction
The Heck reaction is the palladium catalyzed cross-coupling reaction between alkenes and aryl or vinyl halides (or triflates) to afford substituted alkenes.
Molecular Monolayers on Silicon Surfaces
This article briefly reviews the methods and mechanisms for the formation of molecular monolayers on silicon surfaces, the properties of these monolayers and current perspectives regarding their application in molecular electronic and sensing applications.
Galanin Receptors
Sigma-Aldrich offers many products related to galanin receptors for your research needs.
Cannabinoid Receptors
Sigma-Aldrich offers many products related to cannabinoid receptors for your research needs.
InsR
We offers many products related to InsR for your research needs.
Biogenic Amine Transporters
These distinct transporters, NET, DAT and SERT, respectively, are of particular clinical interest because they are the molecular targets for many antidepressants as well as drugs of abuse, such as cocaine and the amphetamines.
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