Erin E Witalison et al.
The Journal of pharmacology and experimental therapeutics, 353(1), 64-70 (2015-01-31)
Ulcerative colitis is a dynamic, idiopathic, chronic inflammatory condition that carries a high colon cancer risk. We previously showed that Cl-amidine, a small-molecule inhibitor of the protein arginine deiminases, suppresses colitis in mice. Because colitis is defined as inflammation of