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Francesca Mion et al.
Journal of immunology (Baltimore, Md. : 1950), 193(9), 4568-4579 (2014-10-01)
The discovery of B cell subsets with regulatory properties, dependent on IL-10 production, has expanded our view on the mechanisms that control inflammation. Regulatory B cells acquire the ability to produce IL-10 in a stepwise process: first, they become IL-10
Thomas F Conway et al.
Journal of Crohn's & colitis, 9(8), 647-658 (2015-05-20)
We investigated oral delivery of transforming growth factor beta 1 [TGFβ]- and all-trans retinoic acid [ATRA]-loaded microspheres as therapy for gut inflammation in murine models of inflammatory bowel disease [IBD]. ATRA and TGFβ were separately encapsulated in poly [lactic-co-glycolic] acid
Juan J Pinto et al.
Talanta, 142, 84-89 (2015-05-25)
During the last decade, hollow fiber liquid phase micro-extraction (HF-LPME) has become an attractive alternative in sample treatment for the analysis of trace metals in seawater. If compared with other similar methodologies, its main advantages are associated to a higher
Slavomíra Poniková et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 20(6), 921-933 (2015-06-17)
We have explored an effect of Hofmeister anions, Na2SO4, NaCl, NaBr, NaNO3, NaSCN and NaClO4, on stability and amyloid fibrillization of hen egg white lysozyme at pH 2.7. The stability of the protein was analyzed by differential scanning calorimetry. The
Yan Zhang et al.
Applied and environmental microbiology, 80(23), 7348-7355 (2014-09-23)
A novel nonheme chloroperoxidase (RhEst1), with promiscuous esterase activity for enantioselective hydrolysis of ethyl (S)-2,2-dimethylcyclopropanecarboxylate, was identified from a shotgun library of Rhodococcus sp. strain ECU1013. RhEst1 was overexpressed in Escherichia coli BL21(DE3), purified to homogeneity, and functionally characterized. Fingerprinting
Gerson F Duarte Junior et al.
Electrophoresis, 36(16), 1935-1940 (2015-03-27)
This paper describes the use of ionic solutions as sensing electrodes for capacitively coupled contactless conductivity detection on electrophoresis microchips. Initially, two channels were engraved in a PMMA holder by using a CO2 laser system and sealed with a thin
Loreen O Villacorte et al.
Water research, 70, 300-312 (2014-12-30)
Transparent exopolymer particles (TEP) and their precursors produced by phyto-/bacterio-planktons in fresh and marine aquatic environments are increasingly considered as a major contributor to organic/particulate and biological fouling in micro-/ultra-filtration and reverse osmosis membrane (RO) systems. However, currently established methods
Agnieszka Karbownik et al.
European journal of drug metabolism and pharmacokinetics, 40(2), 163-170 (2014-03-29)
The study aimed to examine the effect of sunitinib on the plasma exposure of intravenous paracetamol and its major metabolite, paracetamol glucuronide. Both drugs share metabolic pathways in the liver, and the drug interactions between sunitinib and paracetamol administered in
Helioswilton Sales-Campos et al.
International immunopharmacology, 26(1), 13-22 (2015-03-17)
Current therapies for inflammatory bowel disease (IBD) are not totally effective, resulting in persistent and recurrent disease for many patients. Mosquito saliva contains immunomodulatory molecules and therein could represent a novel therapy for IBD. Here, we demonstrated the therapeutic activity
Judith Taibon et al.
Journal of agricultural and food chemistry, 63(23), 5707-5713 (2015-05-26)
The entomopathogenic fungus Metarhizium brunneum is widely applied as a biological pest control agent. Consequently, its use has to be accompanied by a risk management approach, which includes the need to monitor the fate of its bioactive metabolites in the
Rodica Mărgăoan et al.
Journal of agricultural and food chemistry, 62(27), 6306-6316 (2014-06-19)
Total and individual carotenoids, fatty acid composition of total lipids, and main lipid classes of 16 fresh bee-collected pollen samples from Romania were determined by high-performance liquid chromatography with photodiode array detection and capillary gas chromatography with mass detection. Analyzed
Kirstin H Webster et al.
Ecotoxicology (London, England), 24(5), 1087-1101 (2015-04-02)
Based on detection of hepatic residues, scavenging and predatory non-target raptors are widely exposed to second generation anticoagulant rodenticides (SGARs). A small proportion, generally <10%, of tested birds are diagnosed as acutely poisoned. Little is known, however, of sub-lethal effects
Ivana Matić et al.
Journal of chromatography. A, 1364, 117-127 (2014-09-04)
In this paper, development and optimization of new LC-MS method for determination of twenty selected hormones, human/animal and plant sterols in river sediments were described. Sediment samples were prepared using ultrasonic extraction and clean up with silica gel/anhydrous sodium sulphate
Qizhao Wang et al.
Scientific reports, 5, 13593-13593 (2015-09-05)
Morphology-controlled synthesis of CdS can significantly enhance the efficiency of its photocatalytic hydrogen production. In this study, a novel three-dimensional (3D) flower-like CdS is synthesized via a facile template-free hydrothermal process using Cd(NO3)2•4H2O and thiourea as precursors and L-Histidine as
Jignesh Nagar et al.
International immunopharmacology, 21(2), 328-335 (2014-05-27)
Inflammatory bowel disease (IBD) is an idiopathic chronic inflammation of the gastrointestinal tract which is mainly caused by dysregulated gut immune response to commensal flora. Very limited treatment options with marginal efficacy are available along with surgery which has high
Marie Meyer-Monath et al.
Analytical and bioanalytical chemistry, 406(30), 7785-7797 (2014-11-10)
Meconium is the earliest stool of newborns. It is a complex matrix that reflects the degree of fetal exposure to environmental pollutants. To investigate exposure to xenobiotics, an analytical method was developed to identify and quantify some pesticides and their
Hao Lou et al.
Pharmaceutical development and technology, 19(5), 548-555 (2013-06-15)
The purpose of this study is to evaluate the influence of sodium iodide, sodium chloride and sodium sulfate on the formation efficiency of sulfamerazine nanocrystals by wet ball milling. Sulfamerazine was milled using zirconium oxide beads in a solution containing
Daisuke Fujinami et al.
Carbohydrate research, 413, 55-62 (2015-06-22)
The genome of the hyperthermophilic archaeon, Archaeoglobus fulgidus, contains three paralogous AglB genes that encode oligosaccharyltransferase (OST) proteins. The OST enzymes catalyze the transfer of an oligosaccharide chain from lipid-linked oligosaccharides (LLO) to asparagine residues in proteins. The detergent-solubilized membrane
Wim Van Gansbeke et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1001, 221-240 (2015-08-22)
In 2013, the World Anti-Doping Agency (WADA) drastically lowered the minimum required performance levels (MRPLs) of most doping substances, demanding a substantial increase in sensitivity of the existing methods. For a number of compounds, conventional electron impact ionization gas chromatography
Chuan-li Lu et al.
Carbohydrate polymers, 122, 428-436 (2015-03-31)
The rhizomes of Smilax glabra have been used as both food and folk medicine in many countries for a long time. However, little research has been reported on polysaccharides of S. glabra. In the present study, two polysaccharide fractions, SGP-1
Ranganathan Arunkumar et al.
Journal of pharmaceutical sciences, 104(6), 2085-2093 (2015-04-01)
Lutein bioavailability is limited because of its poor aqueous solubility. In this study, lutein-poly (lactic-co-glycolic acid) (PLGA)-polyethylene glycol (PEG) nanocapsules were prepared to improve the solubility, bioavailability, and anticancer property of lutein. The scanning electron microscopy and dynamic light scattering
M N U Al Mahmud et al.
Environmental monitoring and assessment, 187(12), 743-743 (2015-11-13)
This study was conducted to monitor the spread of dichlorodiphenyltrichloroethane (DDT) and its metabolites (dichlorodiphenyldichloroethylene (DDE), dichlorodiphenyldichloroethane (DDD)) in soil and water to regions surrounding a closed DDT factory in Bangladesh. This fulfillment was accomplished using inter-method and inter-laboratory validation
D Zacs et al.
Journal of chromatography. A, 1366, 73-83 (2014-09-30)
An efficient ultra high performance liquid chromatography (UHPLC)-time-of-flight high resolution mass spectrometry (TOF-HRMS) method was elaborated for the determination of hexabromocyclododecane (HBCD) diastereomers in fish samples and compared against UHPLC-Orbitrap-HRMS and UHPLC-triple quadrupole (QqQ) tandem MS (MS/MS) techniques. The TOF-HRMS
Sunita Dashrath Bansod et al.
IET nanobiotechnology, 9(4), 165-171 (2015-08-01)
Many scientists have focused their research on the role of nanotechnology for the control of human pathogens, but there are also many topical pathogens present in animals, which infect animals and transfer to humans. Topical therapy is extremely important for
Erin E Witalison et al.
The Journal of pharmacology and experimental therapeutics, 353(1), 64-70 (2015-01-31)
Ulcerative colitis is a dynamic, idiopathic, chronic inflammatory condition that carries a high colon cancer risk. We previously showed that Cl-amidine, a small-molecule inhibitor of the protein arginine deiminases, suppresses colitis in mice. Because colitis is defined as inflammation of
Chloé de Perre et al.
Archives of environmental contamination and toxicology, 68(4), 745-756 (2015-01-23)
A method was developed for the extraction and analysis of 2 organophosphate, 8 pyrethroid, and 5 neonicotinoid insecticides from the same water sample. A salted liquid-liquid extraction (LLE) was optimized with a solid-phase extraction (SPE) step that separated the organophosphates
Jessica Le Ven et al.
Journal of agricultural and food chemistry, 62(34), 8696-8704 (2014-08-05)
Epidemiological and toxicological studies have suggested Annonaceaeous acetogenins to be environmental neurotoxins responsible for sporadic atypical parkinsonism/dementia in tropical areas. These compounds are present in the tropical genus Annona (Annonaceae), known for its fruit-yielding cultivated species such as Annona cherimolia.
Sudeep Tiwari et al.
Protoplasma, 251(5), 1089-1098 (2014-02-12)
An endophytic fungus was isolated from the rhizomes of Curcuma amada (Zingiberaceae), which was identified as Fusarium oxysporum on the basis of its morphological and molecular characters. Chromatographic separation and spectroscopic analysis of the fungal metabolite (chloroform extract) led to
O I Olukunle et al.
Ecotoxicology and environmental safety, 120, 394-399 (2015-06-29)
Information on polybrominated diphenyl ethers (PBDEs) in the indoor environment in developing countries is still relatively scarce. In this study, house (n=10) and office (n=11) dusts samples collected from Makurdi, Benue State Nigeria were extracted and analysed for most abundant
Hong Li et al.
Journal of the Air & Waste Management Association (1995), 63(4), 442-452 (2013-05-22)
Litter amendments have been used to control the ammonia (NH3) emission from the broiler litter during the brooding period. One of the commercially available litter amendments, sodium bisulfate, was frequently applied on the litter with two different rates on weekly
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