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PHL89270

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Debendranath Dey et al.
Evidence-based complementary and alternative medicine : eCAM, 2020, 6428906-6428906 (2020-04-21)
Excessive alcohol consumption is a worldwide threat with severe morbidity and mortality. Other than abstinence, there is still no FDA-approved drug for alcoholic liver disease (ALD). Liver is the primary site of ethanol metabolism and hence gets the most damage...
Marwa M Abu-Serie et al.
Scientific reports, 10(1), 2452-2452 (2020-02-14)
Human is subjected from his surrounding to various hepatotoxins, which aggravates his liver. Nowadays, natural polyphenols have attracted great interest in health improvement, especially liver health. The present research, therefore, assessed the hepatotherapeutic potency of the isolated polyphenols (VVF1) from...
Jong Min Kim et al.
Food science and biotechnology, 29(9), 1261-1271 (2020-08-18)
This study was conducted to evaluate the storage conditions of matcha (Camellia sinensis) according to temperature during 2 months. The moisture content of matcha tend to decrease with increasing temperature. To evaluate the brightness and green value of matcha, changes in...
Alessandra Moraes Pedrosa et al.
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 28(1), 281-286 (2020-04-15)
Triterpenes are ubiquitous secondary metabolites present in plants. They can be found in both forms, as genins or conjugated as glycosides. Although distinct analytical methods to quantify these compounds in vegetal tissues are available in the literature, limitations like high...
Johana Lopez-Polo et al.
Food research international (Ottawa, Ont.), 130, 108967-108967 (2020-03-12)
The potential use of liposomes as carriers for food active ingredients can be limited by their physical and chemical instabilities in aqueous dispersions, especially for long-term storage. Lyophilization, a process commonly used in the food industry, can also be applied...
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Carlos Areche et al.
Frontiers in pharmacology, 11, 417-417 (2020-04-24)
Corryocactus brevistylus (K. Schum. ex Vaupel) Britton & Rose (Cactaceae) is a shrubby or often arborescent cactus popularly known as "sancayo" and produce an edible fruit known as "Sanky" which is consumed in Arequipa-Perú. The purpose of this study was...
Keshav Raj Paudel et al.
Toxicology in vitro : an international journal published in association with BIBRA, 68, 104961-104961 (2020-08-11)
Airway inflammation and infections are the primary causes of damage in the airway epithelium, that lead to hypersecretion of mucus and airway hyper-responsiveness. The role of reactive oxygen species (ROS) and their components in the pathophysiological mechanisms of airway inflammation...
Qincao Chen et al.
Food chemistry, 332, 127412-127412 (2020-07-06)
In this study, metabolomics and proteomics were employed to investigate the change mechanism of nonvolatile compounds during white tea processing. A total of 99 nonvolatile compounds were identified, among which the contents of 13 free amino acids, caffeine, theaflavins, 7...
Abdelhadi El Jaouhari et al.
Analytica chimica acta, 1106, 103-114 (2020-03-09)
Exceptional sensitivity behavior of molecularly imprinted polymer (MIP) approach towards an electrochemical sensor application encourages combining this approach with other materials to tune their properties such as large surface area, high catalytic effect, electrical, thermal and mechanical stability for the...
Huan Guo et al.
Experimental and therapeutic medicine, 19(1), 557-568 (2020-01-04)
Apocynum venetum is a traditional medicine that is rich in polyphenols. Apocynum venetum polyphenol extract (AVP) contains the active substances neochlorogenic acid, chlorogenic acid, rutin, isoquercitrin, astragaloside and rosmarinic acid. In the present study, the preventive effect of AVP against...
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Antonis Ververis et al.
Evidence-based complementary and alternative medicine : eCAM, 2020, 2975284-2975284 (2021-01-29)
Alzheimer's disease (AD) is the most common neurodegenerative disease, affecting the elderly at a high incidence. AD is of unknown etiology and currently, no cure is available. Present medication is restricted to treating symptoms; thus, a need exists for the...
Amina Labdelli et al.
Plants (Basel, Switzerland), 9(9) (2020-08-23)
Phenolic compounds are secondary metabolites that occur naturally in all plants. Seeds are among the richest organs of plants in phytochemicals, vitamins and minerals. These compounds and their biological activities are of great importance for human health. This study aimed...
Nisha Dhiman et al.
Scientific reports, 10(1), 17186-17186 (2020-10-16)
The study is the first report on de novo transcriptome analysis of Nardostachys jatamansi, a critically endangered medicinal plant of alpine Himalayas. Illumina GAIIx sequencing of plants collected during end of vegetative growth (August) yielded 48,411 unigenes. 74.45% of these...
Luciana Fentanes Moura de Melo et al.
Oxidative medicine and cellular longevity, 2020, 3928706-3928706 (2020-10-27)
The genus Coccoloba is widely used in traditional folk medicine, but few scientific data exist for this genus. The goal of this study was to characterise the chemical composition and antioxidant activities of C. alnifolia leaf extracts using in vitro...
Paula Mendonça Leite et al.
Journal of cardiovascular pharmacology, 74(6), 574-583 (2019-12-10)
Mikania laevigata, popularly known in Brazil as guaco, is widely used for respiratory disorders. As this plant is rich in coumarins, there is evidence of indications that it may cause bleeding and therefore should not be used concomitantly with anticoagulants....
Chunhua Zhu et al.
Chemistry & biodiversity, 17(6), e1900690-e1900690 (2020-04-21)
A large number of biologically active compounds are present in ripe citrus fruits. However, few studies have been focused on the changes in flavonoids and the evolution of antioxidant activity during citrus fruit growth. In this study, fruits of five...
Haroldo C Da Silva et al.
ACS omega, 5(6), 3030-3042 (2020-02-26)
Coordination compounds formed by flavonoid ligands are recognized as promising candidates as novel drugs with enhanced antioxidant and anticancer activity. Zn(II)-Rutin complexes have been described in the literature and distinct coordination modes proposed based on 1H NMR/MS and IR/UV-VIS experimental...
Vlasios Goulas et al.
Foods (Basel, Switzerland), 9(1) (2019-12-28)
The goal of this study was to explore the potential of carob extracts to act as lipid inhibitors in model food systems. First, the extraction efficacy of fourteen solvents on the phenolic and flavonoid contents as well as on the...
Na Li et al.
Recent patents on nanotechnology, 14(1), 35-41 (2019-11-09)
The electrospinning and the bubble electrospinning provide facile ways for the fabrication of functional nanofibers by incorporating rutin/hydroxypropyl-β-cyclodextrin inclusion complex (RT/HP-β-CD-IC) in Polyvinyl Alcohol (PVA). Few patents on incorporation of rutin and cyclodextrin in nanofibers has been reported. The study...
Larissa Marafiga Cordeiro et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 141, 111323-111323 (2020-04-12)
Huntington's disease (HD) is inherited neurodegenerative disease, it is characterized by excessive motor movements and cognitive and emotional deficits. HD is caused by an abnormally long polyglutamine (polyQ) expansion in the huntingtin (Htt) protein, which confers toxic functions to mutant...
Gina Paola Domínguez Moré et al.
The Journal of pharmacy and pharmacology, 72(5), 738-747 (2020-03-13)
The Biopharmaceutics Classification System (BCS) categorizes active pharmaceutical ingredients according to their solubility and permeability properties, which are susceptible to matrix or formulation effects. The aim of this research was to evaluate the matrix effects of a hydroethanolic extract of...
Yin Wang et al.
Food chemistry, 337, 127774-127774 (2020-08-11)
Apis cerana honey collected from the Qinling Mountains in China has been widely used for its antimicrobial property in traditional Chinese medicine. However, its antibacterial mechanism against Salmonella Typhimurium LT2 is still uncertain. A total of 52 volatile components were...
E J Llorent-Martínez et al.
Food research international (Ottawa, Ont.), 129, 108798-108798 (2020-02-11)
Broccolini is originated from crossing the regular broccoli with Chinese kale. Consequently, it has similar properties to these vegetables, but other very particular characteristics. Its consumption has increased in the last few years and, consequently, there have been some studies...
Cherdsak Boonyong et al.
The Journal of pharmacy and pharmacology, 72(4), 583-591 (2020-01-11)
Indomethacin (INDO) and diclofenac (DIC) can induce intestinal cell death through induction of oxidative stress-mediated ER stress and mitochondrial dysfunction. This study investigated the cytoprotective potential of 11 polyphenols, namely caffeic acid (CAF), curcumin (CUR), epigallocatechin gallate (EGCG), gallic acid...
Dragana Č Dabić Zagorac et al.
Journal of separation science, 43(8), 1431-1439 (2020-01-31)
The profile of flavan-3-ols and proanthocyanidins in five different Rosa species (R. canina, R. glutinosa, R. rubiginosa, R. multiflora, and R. spinosissima) was estimated on high performance thin layer chromatography cellulose plates. Differences in flavanol and proanthocyanidin profiles of the extracts were evident, among...
Oumaima Ghomari et al.
Journal of microbiological methods, 176, 106010-106010 (2020-07-28)
In the present study we aimed firstly to assess the resistance of a set of yeasts, isolated from the black olive pomace, to various phenolic compounds; and to evaluate their growth capacities on an olive leaf extract rich of oleuropein....
Yi Qian et al.
Ecotoxicology and environmental safety, 201, 110879-110879 (2020-06-20)
Per- and polyfluoroalkyl substances (PFASs) are toxic to microorganisms, thereby affecting microbial communities in sludge and soil, but how to repair the toxicity of microorganisms remains unclear. In this study, rutin, an antioxidant, was added into a culture medium with...
Hamit Çelik et al.
Molecular biology reports, 47(3), 2023-2034 (2020-02-08)
The purpose of the current study was to examine the neuroprotective effect of rutin against colistin-induced neurotoxicity in rats. Thirty-five male Sprague Dawley rats were randomly divided into 5 groups. The control group (orally received physiological saline), the rutin group...
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