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Juan Martín D'Ambrosio et al.
Plant physiology, 175(2), 970-981 (2017-08-23)
The activation of phosphoinositide-specific phospholipase C (PI-PLC) is one of the earliest responses triggered by the recognition of several microbe-associated molecular patterns (MAMPs) in plants. The Arabidopsis (
Yuan Lin et al.
Frontiers in plant science, 9, 1379-1379 (2018-10-05)
Therapeutic monoclonal antibodies (mAbs) have evolved into an important class of effective medicine in treatment of various diseases. Since the antibody molecule consists of two identical heavy chains (HC) and two light chains (LC), each chain encoded by two different
Kayla M Harmeyer et al.
Nucleic acids research, 43(6), e38-e38 (2014-12-30)
Genome-wide chromatin immunoprecipitation (ChIP) studies have brought significant insight into the genomic localization of chromatin-associated proteins and histone modifications. The large amount of data generated by these analyses, however, require approaches that enable rapid validation and analysis of biological relevance.
Yuanxue Liang et al.
Plant physiology, 179(4), 1502-1514 (2019-02-08)
Nitrogen (N) starvation-induced triacylglycerol (TAG) synthesis, and its complex relationship with starch metabolism in algal cells, has been intensively studied; however, few studies have examined the interaction between amino acid metabolism and TAG biosynthesis. Here, via a forward genetic screen
Chengsong Zhao et al.
The New phytologist, 216(1), 76-89 (2017-07-26)
The Arabidopsis thaliana gene XYLEM NAC DOMAIN1 (XND1) is upregulated in xylem tracheary elements. Yet overexpression of XND1 blocks differentiation of tracheary elements. The molecular mechanism of XND1 action was investigated. Phylogenetic and motif analyses indicated that XND1 and its
Bhavesh C Variya et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 73, 152906-152906 (2019-05-09)
Nature has gifted a variety of vital phytochemicals having potential therapeutic application against various ailments. Emblica officinalis (E. officinalis), an ancient plant, has long been used as a remedy for diabetes and cardiovascular complications, and presence of abundant amount of
Xueli Lu et al.
BMC plant biology, 19(1), 170-170 (2019-05-02)
Endo-β-1,4-xylanase1 (EA), the key endoxylanase in plants, is involved in the degradation of arabinoxylan during grain germination. In barley (Hordeum vulgare L.), one gene (HvXYN-1) that encode a endo-beta-1,4-xylanase, has been cloned. However, the single nucleotide polymorphisms (SNPs) that affect
Pengfei Cao et al.
eLife, 8 (2019-12-07)
The target of rapamycin (TOR) kinase is an evolutionarily conserved hub of nutrient sensing and metabolic signaling. In plants, a functional connection of TOR activation with glucose availability was demonstrated, while it is yet unclear whether branched-chain amino acids (BCAAs)
Vincenzo Lionetti et al.
PloS one, 10(7), e0133810-e0133810 (2015-07-24)
Pectin is secreted in a highly methylesterified form and partially de-methylesterified in the cell wall by pectin methylesterases (PMEs). PME activity is expressed during plant growth, development and stress responses. PME activity is controlled at the post-transcriptional level by proteins
Marie-Pierre Dubrana et al.
Journal of molecular biology, 429(12), 1889-1902 (2017-05-16)
Mollicutes, including mycoplasmas and spiroplasmas, have been considered as good representatives of the « minimal cell » concept: these wall-less bacteria are small in size and possess a minimal genome and restricted metabolic capacities. However, the recent discovery of the
Zhiyang Zhai et al.
The Plant cell, 30(10), 2616-2627 (2018-09-27)
WRINKLED1 (WRI1), the transcriptional activator of fatty acid synthesis, was recently identified as a target of KIN10, a catalytic α-subunit of the SUCROSE-NON-FERMENTING1-RELATED PROTEIN KINASE1 (SnRK1). We tested the hypothesis that trehalose 6-phosphate (T6P), a signal of cellular sucrose status
Esther Zúñiga-Sánchez et al.
Physiologia plantarum, 165(3), 632-643 (2018-05-17)
Legume seed development represents a high demand for energy and metabolic resources to support the massive synthesis of starch and proteins. However, embryo growth occurs in an environment with reduced O2 that forces the plant to adapt its metabolic activities
Juan Wang et al.
The Plant cell, 32(2), 414-428 (2019-12-13)
UBL-UBA (ubiquitin-like-ubiquitin-associated) proteins are ubiquitin receptors and transporters in the ubiquitin-proteasome system that play key roles in plant growth and development. High salinity restricts plant growth by disrupting cellular metabolism, but whether UBL-UBA proteins are involved in this process is
Marco Biancucci et al.
BMC plant biology, 15, 263-263 (2015-10-31)
We reported previously that root elongation in Arabidopsis is promoted by exogenous proline, raising the possibility that this amino acid may modulate root growth. To evaluate this hypothesis we used a combination of genetic, pharmacological and molecular analyses, and showed
Yu Yang et al.
Nucleic acids research, 45(1), 181-197 (2016-09-28)
Epigenetic regulation is important for organismal development and response to the environment. Alteration in epigenetic status has been known mostly from the perspective of enzymatic actions of DNA methylation and/or histone modifications. In a genetic screen for cellular factors involved
Ulrich Hohmann et al.
Nature plants, 4(6), 345-351 (2018-05-08)
The leucine-rich repeat receptor kinase (LRR-RK) BRASSINOSTEROID INSENSITIVE 1 (BRI1) requires a shape-complementary SOMATIC EMBRYOGENESIS RECEPTOR KINASE (SERK) co-receptor for brassinosteroid sensing and receptor activation1. Interface mutations that weaken the interaction between receptor and co-receptor in vitro reduce brassinosteroid signalling
Yangping Li et al.
Plant science : an international journal of experimental plant biology, 274, 332-340 (2018-08-07)
The accumulation of starch in cereal endosperm is a key process that determines crop yield and quality. Research has reported that sucrose and abscisic acid (ABA) synergistically regulate the synthesis of crop starch. However, little is known about the molecular
Amy Huei-Yi Lee et al.
PLoS pathogens, 8(2), e1002523-e1002523 (2012-02-10)
The eukaryotic cytoskeleton is essential for structural support and intracellular transport, and is therefore a common target of animal pathogens. However, no phytopathogenic effector has yet been demonstrated to specifically target the plant cytoskeleton. Here we show that the Pseudomonas
Concepción Iñiguez et al.
Journal of experimental botany, 70(4), 1283-1297 (2018-12-24)
Despite the high productivity and ecological importance of seaweeds in polar coastal regions, little is known about their carbon utilization mechanisms, especially the kinetics of the CO2-fixing enzyme Rubisco. We analyzed Rubisco carboxylation kinetics at 4 °C and 25 °C
Alexander Frank et al.
Current biology : CB, 28(16), 2597-2606 (2018-08-07)
Synchronization of circadian clocks to the day-night cycle ensures the correct timing of biological events. This entrainment process is essential to ensure that the phase of the circadian oscillator is synchronized with daily events within the environment [1], to permit
Chun-Hong Li et al.
Pharmaceutical biology, 55(1), 76-87 (2016-09-23)
Corydalis yanhusuo W.T. Wang (Papaveraceae) (Rhizoma Corydalis) showed inhibitory effects on rabbit platelet aggregation induced by ADP, thrombin (THR) or arachidonic acid (AA). This study separates and identifies the possible target-related platelet proteins and suggests possible signal cascades of RC
Clémence Henry et al.
Plant physiology, 169(2), 1072-1089 (2015-08-14)
Little is known about how salt impacts primary metabolic pathways of C4 plants, particularly related to kernel development and seed set. Osmotic stress was applied to maize (Zea mays) B73 by irrigation with increasing concentrations of NaCl from the initiation
Benjamin Schwessinger et al.
PLoS genetics, 7(4), e1002046-e1002046 (2011-05-20)
Plants rely heavily on receptor-like kinases (RLKs) for perception and integration of external and internal stimuli. The Arabidopsis regulatory leucine-rich repeat RLK (LRR-RLK) BAK1 is involved in steroid hormone responses, innate immunity, and cell death control. Here, we describe the
Peiwei Liu et al.
The Journal of cell biology, 219(6) (2020-04-30)
Mutations in the channel protein PKD2 cause autosomal dominant polycystic kidney disease, but the function of PKD2 in cilia remains unclear. Here, we show that PKD2 targets and anchors mastigonemes, filamentous polymers of the glycoprotein MST1, to the extracellular surface
Yong Yang et al.
Molecular biology of the cell, 22(7), 976-987 (2011-02-04)
Eukaryotic cilia and flagella are vital sensory and motile organelles. The calcium channel PKD2 mediates sensory perception on cilia and flagella, and defects in this can contribute to ciliopathic diseases. Signaling from Pkd2-dependent Ca²+ rise in the cilium to downstream
Venkatasalam Shanmugabalaji et al.
Frontiers in plant science, 11, 2-2 (2020-02-23)
Heme plays an active role in primary plant metabolic pathways as well as in stress signaling. In this study, we characterized the predicted heme-binding protein SOUL4. Proteomics evidence suggests that SOUL4 is a component of Arabidopsis plastoglobules (PGs, chloroplast lipid
An evolutionarily distinct chaperone promotes 20S proteasome ?-ring assembly in plants.
Marshall, et al.
Journal of Cell Science, 133 (2021)
Jia-Jia Han et al.
The New phytologist, 220(2), 476-487 (2018-07-06)
DNA replication is a fundamental process for the faithful transmission of genetic information in all living organisms. Many endogenous and environmental signals impede fork progression during DNA synthesis, which induces replication errors and DNA replication stress. Chromatin remodeling factors regulate
Inkar Castellanos-Huerta et al.
Avian diseases, 60(4), 784-791 (2016-12-03)
Globally, avian influenza (AI) is a serious problem in poultry farming. Despite vaccination, the prevalence of AI in México highlights the need for new approaches to control AI and to reduce the economic losses associated with its occurrence in susceptible
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