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Jia Liu et al.
Carbohydrate polymers, 94(1), 539-546 (2013-04-03)
To better use wheat straw and minimize its negative impact on environment, a novel semi-interpenetrating polymer networks (semi-IPNs) superabsorbent resin (SAR) composed of wheat straw cellulose-g-poly (potassium acrylate) (WSC-g-PKA) network and linear polyvinyl alcohol (PVA) was prepared by polymerization in
Emna Bouchaâla et al.
Applied biochemistry and biotechnology, 176(1), 151-169 (2015-03-22)
In order to identify fish enzymes displaying novel biochemical properties, we have chosen the common stingray (Dasyatis pastinaca), one of the most primitive living jawed aquatic vertebrates as a starting biological material to purify a lipase. A stingray pancreatic lipase
Ufuk Kuyrukluyıldız et al.
International journal of clinical and experimental medicine, 8(4), 5691-5698 (2015-07-02)
Backround: Surgical operations are alternative treatments in persons with Obstructive Sleep Apnea Syndrome who cannot tolerate continuous positive airway pressure therapy. Drug-Induced Sleep Endoscopy is a method with which somnolence is pharmacologically induced and collapse is evaluated through nasal endoscopy
Chaenyung Cha et al.
Journal of biomaterials science. Polymer edition, 26(13), 828-840 (2015-06-13)
Poly(lactic-co-glycolic acid) (PLGA) microspheres have been widely used as drug carriers for minimally invasive, local, and sustained drug delivery. However, their use is often plagued by limited controllability of encapsulation efficiency, initial burst, and release rate of drug molecules, which
Christopher A Dieni et al.
PeerJ, 2, e558-e558 (2014-09-12)
The wood frog, Rana sylvatica, survives whole-body freezing and thawing each winter. The extensive adaptations required at the biochemical level are facilitated by alterations to signaling pathways, including the insulin/Akt and AMPK pathways. Past studies investigating changing tissue-specific patterns of
Timothy G Short et al.
Anesthesia and analgesia, 121(2), 357-365 (2015-05-21)
An association between relatively deep anesthesia, as guided by the bispectral index (BIS), and increased postoperative mortality has been demonstrated in 6 of 8 published observational studies, but association does not necessarily mean causality. Small clinical trials of anesthetic depth
C Zeng et al.
Bioorganic & medicinal chemistry, 23(17), 5702-5708 (2015-07-30)
The T box riboswitch is an intriguing potential target for antibacterial drug discovery. Found primarily in Gram-positive bacteria, the riboswitch regulates gene expression by selectively responding to uncharged tRNA to control transcription readthrough. Polyamines and molecular crowding are known to
Farzaneh Rafie et al.
Current eye research, 35(12), 1081-1089 (2010-10-22)
The purpose of this study was to investigate the in vivo effects of a new smart polymer loaded with dexamethasone on inflamed rabbit eye. Polymeric micelles were prepared using N-isopropylacrylamide (NIPAAM), vinyl pyrrolidone (VP), and methacrylate (MAA) as monomers in
Shaoxuan Yu et al.
Nanotechnology, 26(14), 145703-145703 (2015-03-19)
Selenium nanoparticles (Se NPs) possess well-known excellent biological activities and low toxicity, and have been employed for numerous applications except as inhibitors to protein glycation. Herein, the present study is carried out to investigate the inhibitory effect of Se NPs
Yu Liu et al.
PloS one, 10(4), e0123862-e0123862 (2015-04-18)
The CONCERT-CL closed-loop infusion system designed by VERYARK Technology Co., Ltd. (Guangxi, China) is an innovation using TCI combined with closed-loop controlled intravenous anesthesia under the guide of BIS. In this study we performed a randomized, controlled, multicenter study to
Tobias Werther et al.
Neonatology, 107(1), 34-41 (2014-10-18)
The lower margin amplitude (LMA) of the amplitude-integrated electroencephalogram (aEEG) is suppressed in neonates during deep sedation, a feature that is attributed to the bispectral index (BIS) in adults. We compare the BIS and the LMA of the aEEG in
Guoqiang Liu et al.
Small (Weinheim an der Bergstrasse, Germany), 11(23), 2807-2816 (2015-02-05)
A facile route to fabricate a nanocomposite of Fe3O4@poly[N-isopropylacrylamide (NIPAM)-co-2-(dimethylamino)ethyl methacrylate (DMAEMA)]@Au (Fe3O4@PND@Au) is developed for magnetically recyclable and thermally tunable catalysis. The negatively charged Au nanoparticles with an average diameter of 10 nm are homogeneously loaded onto positively charged
Yi-Wei Huang et al.
Journal of cellular physiology, 230(9), 2086-2097 (2015-02-03)
Ca(2+) -mediated formation of cell polarity is essential for directional migration which plays an important role in physiological and pathological processes in organisms. To examine the critical role of store-operated Ca(2+) entry, which is the major form of extracellular Ca(2+)
Kıvılcım Çaktü et al.
Artificial cells, nanomedicine, and biotechnology, 42(6), 365-375 (2013-12-07)
Cholesterol-imprinted monosize poly(glycidyl methacrylate-N-methacryloyl-(L)-tyrosine methylester) microspheres were embedded into the poly(hydroxyethyl methacrylate) (PHEMA) cryogels and the resulting composite cryogel was used for the selective removal of cholesterol. Composite cryogels were characterized by swelling tests, multipoint BET apparatus, SEM, FTIR and
Marta Puig et al.
Molecular cancer research : MCR, 13(1), 161-173 (2014-10-05)
The crucial role of tumor-associated fibroblasts (TAF) in cancer progression is now clear in non-small cell lung cancer (NSCLC). However, therapies against TAFs are limited due to a lack of understanding in the subtype-specific mechanisms underlying their accumulation. Here, the
Jintian Cheng et al.
Electrophoresis, 34(8), 1189-1196 (2013-02-14)
A polar polymethacrylate-based monolithic column was introduced and evaluated as a hydrophilic interaction CEC stationary phase. The monolithic stationary phase was prepared by in situ copolymerization of a neutral monomer 2-hydroxyethyl methacrylate and a polar cross-linker N,N'-methylene bisacrylamide in a
Multicolor polymer-dispersed liquid crystal.
Naomi Kumano et al.
Advanced materials (Deerfield Beach, Fla.), 23(7), 884-888 (2010-12-29)
Dariusz Suchy et al.
Naunyn-Schmiedeberg's archives of pharmacology, 387(8), 733-742 (2014-05-02)
Macrophages are crucial for the development of atherosclerotic plaques. Classically activated macrophages contribute to plaque growth and destabilization, while alternatively activated macrophages increase plaque stability. Here, we assessed the influence of ezetimibe on the activation of monocyte-derived macrophages isolated from
Srinivasa Raju Datla et al.
American journal of physiology. Heart and circulatory physiology, 307(7), H945-H957 (2014-07-27)
Polymerase-δ-interacting protein 2 (Poldip2) interacts with NADPH oxidase 4 (Nox4) and regulates migration; however, the precise underlying mechanisms are unclear. Here, we investigated the role of Poldip2 in focal adhesion turnover, as well as traction force generation and polarization. Poldip2
Gustavo Bodelón et al.
Small (Weinheim an der Bergstrasse, Germany), 11(33), 4149-4157 (2015-05-06)
Detection technologies employing optically encoded particles have gained much interest toward clinical diagnostics and drug discovery, but the portfolio of available systems is still limited. The fabrication and characterization of highly stable surface-enhanced resonance Raman scattering (SERRS)-encoded colloids for the
Nikola Milašinović et al.
International journal of pharmaceutics, 436(1-2), 332-340 (2012-07-05)
The series of poly(N-isopropylacrylamide-co-itaconic acid) hydrogels, with lipase from Candida rugosa as a model protein, were synthesized by free radical copolymerization. The composition of hydrogels was varied by monomers ratio, crosslinking agent concentration and amounts of lipase, which was loaded
Aurélie Schoubben et al.
International journal of pharmaceutics, 491(1-2), 91-98 (2015-06-02)
Conventional injection is still the leading method to deliver macromolecular therapeutics. Needle injection is considered a low compliance administration strategy, principally due to pain and needle phobia. This has fostered the research on the development of alternative strategies to circumvent
Shan Jiang et al.
Journal of chromatography. A, 1412, 75-81 (2015-08-25)
Mass spectrometry (MS) coupled to sample preparation and separation techniques has become a primary tool for proteomics studies. However, due to sample complexity, it is often challenging to achieve fast and efficient sample preparation prior to MS analysis. In recent
A J Aho et al.
British journal of anaesthesia, 115(2), 258-266 (2015-07-04)
Concomitantly recorded Bispectral Index® (BIS) and Entropy™ values sometimes show discordant trends during general anaesthesia. Previously, no attempt had been made to discover which EEG characteristics cause discrepancies between BIS and Entropy. We compared BIS and Entropy values, and analysed
Karina Pires Reis et al.
Alcohol (Fayetteville, N.Y.), 49(7), 665-674 (2015-09-01)
Ethanol exposure to offspring during pregnancy and lactation leads to developmental disorders, including central nervous system dysfunction. In the present work, we have studied the effect of chronic ethanol exposure during pregnancy and lactation on the phosphorylating system associated with
David R Kryscio et al.
Analytica chimica acta, 718, 109-115 (2012-02-07)
Molecularly imprinted polymers are synthetic antibody mimics formed by the crosslinking of organic or inorganic polymers in the presence of an analyte which yields recognitive polymer networks with specific binding pockets for that biomolecule. Surface imprinted polymers were synthesized via
Wei-Hong Li et al.
Microcirculation (New York, N.Y. : 1994), 21(6), 506-515 (2014-03-05)
This study was designed to evaluate whether exogenous CRT was beneficial for alleviating MR-induced injury by suppressing ER stress in rat MMECs. MMECs were pretreated with CRT (25 pg/mL) for 12 hours, followed by the exposure to 2.856 GHz radiation
Bijaya Upadhyaya et al.
Experimental eye research, 130, 58-65 (2014-12-06)
Glutaredoxin2 (Grx2) is a mitochondrial isozyme of the cytosolic glutaredoxin1 (thioltransferase or TTase). Both belong to the large oxidoreductase family and play an important role in maintaining thiol/disulfide redox homeostasis in the cells. Grx2 is recently found in the lens
David E Lovett et al.
Addictive behaviors, 48, 58-61 (2015-05-23)
Research using alcohol-related visual stimuli has been limited due to a lack of published studies examining the psychometric properties of alcohol cues. The primary aim of the current study was to examine the factor structure, validity, and reliability of craving
Daiane Gil Franco et al.
PloS one, 9(9), e106332-e106332 (2014-09-04)
The constitutive activation of nuclear factor-κB (NF-κB), a key transcription factor involved in neuroinflammation, is essential for the survival of neurons in situ and of cerebellar granule cells in culture. Melatonin is known to inhibit the activation of NF-κB and
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