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lh20100
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P Kolodziejczyk et al.
Free radical biology & medicine, 5(1), 13-25 (1988-01-01)
Ambient temperature incubation of the anticancer agent mitoxantrone with horseradish peroxidase and hydrogen peroxide converts it into a hexahydronaphtho[2,3-f]quinoxaline-7,12-dione in which one side chain has cyclized to the chromophore. The structure of this cyclic metabolite was secured by independent synthesis.
Beatriz Pereira Moreno et al.
Chemistry & biodiversity, 17(3), e1900694-e1900694 (2020-02-06)
Studies of the phytotoxic effects between plants can be a crucial tool in the discovery of innovative compounds with herbicide potential. In this sense, we can highlight ruzigrass (Urochloa ruziziensis), which is traditionally used in the crop rotation system in
Tony Velkov et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 867(2), 238-246 (2008-05-06)
Cellular lipids frequently co-purify with lipid binding proteins isolated from tissue extracts or heterologous host systems and as such hinder in vitro ligand binding approaches for which the apo-protein is a prerequisite. Here we present a technique for the complete
A K Tandon et al.
Cancer research, 46(7), 3375-3377 (1986-07-01)
We described recently a modified charcoal-gelatin (MCG) assay for measuring progesterone receptor activity in low-protein cytosols. We showed that pre-mixing of gelatin with sample cytosols (final gelatin concentration 0.1%) and removal of unbound steroid by a 1% charcoal suspension with
A Cahouet et al.
International journal of pharmaceutics, 242(1-2), 367-371 (2002-08-15)
The aim of the present work was to study the biodistribution of a radiolabeled lipidic nanocapsule formulation after intravenous administration in rat by scintigraphy and gamma counting. This formulation is expected to be used as anticancer agent delivery devices and
Attila Hunyadi et al.
PloS one, 6(8), e23922-e23922 (2011-09-14)
Protoapigenone, a natural flavonoid possessing an unusual p-quinol moiety on its B-ring, is a novel prospective anticancer agent with low toxicity that is currently in development. The first economical, one-step synthesis of protoapigenone from apigenin is described on up to
Z Piskornik et al.
Plant physiology, 50(1), 176-182 (1972-07-01)
The "bound auxin" of Zea mays, first described by Berger and Avery (Amer. J. Bot. 1944; 31: 199-203) has been purified and partially characterized. It is an indole-3-acetic acid-containing, high molecular weight, lipophilic cellulosicglucan. The indole-3-acetic acid is in ester
Y Jiang et al.
International journal of food sciences and nutrition, 61(4), 346-356 (2010-05-15)
Various vegetables were investigated for antioxidant activities in two assays, namely, inhibition of lysis of erythrocytes induced by peroxyl radicals and inhibition of lipid peroxidation. The lotus (Nelumbo nucifera Gaertn) rhizome showed the strongest antioxidant activity in both assays. The
Hui Shao et al.
Macromolecular bioscience, 9(5), 464-471 (2008-12-02)
Polyacrylate glue protein analogs of the glue secreted by Phragmatopoma californica, a marine polycheate, were synthesized with phosphate, primary amine, and catechol sidechains with molar ratios similar to the natural glue proteins. Aqueous mixtures of the mimetic polyelectrolytes condensed into
Encapsulated three-dimensional culture supports development of nonhuman primate secondary follicles.
Min Xu et al.
Biology of reproduction, 81(3), 587-594 (2009-05-29)
In vitro ovarian follicle cultures may provide fertility-preserving options to women facing premature infertility due to cancer therapies. An encapsulated three-dimensional (3-D) culture system utilizing biomaterials to maintain cell-cell communication and support follicle development to produce a mature oocyte has
The source, composition and flux of polycyclic aromatic hydrocarbons in sediments of the river Derwent, Derbyshire, U.K.
Evans, K.M., et al.
Water, Air, Soil Pollut., 51(1-2), 1-12 (1990)
Eric W C Chan et al.
Pharmacognosy research, 3(3), 178-184 (2011-10-25)
Chlorogenic acid (CGA) or 5-caffeoylquinic acid, was found to be the dominant phenolic compound in leaves of Etlingera elatior (Zingiberaceae). The CGA content of E. elatior leaves was significantly higher than flowers of Lonicera japonica (honeysuckle), the commercial source. In
Suman B Sharma et al.
Journal of medicinal food, 14(4), 353-359 (2011-03-05)
Diabetes is accompanied by lipid abnormalities, which contribute significantly to cardiovascular morbidity and mortality in diabetic patients. We previously demonstrated the potent antihyperglycemic activity of the active principle (fraction II from Sephadex LH 20 chromatography [LH II]) isolated from ethanolic
Edith O Cuevas-Rodríguez et al.
Journal of agricultural and food chemistry, 58(12), 7458-7464 (2010-05-29)
This study was designed to characterize and compare wild, commercial, and noncommercial cultivated blackberry genotypes grown in Michoacan, Mexico. Six genotypes, including WB-3, WB-7, WB-10, and WB-11 (all wild blackberry types), Tupy (a commercial cultivar), and UM-601 (a cultivated breeding
J P Brown et al.
Mutation research, 66(3), 223-240 (1979-03-01)
Over 70 naturally occurring and synthetic flavonoids were screened for mutagenicity with 5 tester strains in the Salmonella/mammalian microsome assay: TA1535, TA100, TA1537, TA1538 and TA98. Frameshift mutagenicity was confined to the flavonols (flavon-3-ols) in strain TA98, TA1537 and TA100.
N X Chen et al.
Journal of animal science, 73(3), 722-727 (1995-03-01)
Previous studies have shown that the responsiveness of porcine preadipocytes to glucocorticoids increases progressively with fetal age. In the current study, the development of fetal glucocorticoid receptors in porcine preadipocytes was examined in primary cultures derived from 50-, 75-, and
D Pechinot et al.
Journal of steroid biochemistry, 18(5), 601-606 (1983-05-01)
A procedure for the determination of corticosterone in 20 microliters of rat plasma, in maternal and foetal late pregnancy with a protein binding radioassay, is described. The method is suitable in a range of 0.5-3 ng of corticosterone. An amount
Yizhong Cai et al.
Journal of chromatographic science, 43(9), 454-460 (2005-10-11)
HPLC characterization of reversed-phase (RP) high-performance liquid chromatography (HPLC) has been widely used in separation and identification of plant pigments. An effective RP-HPLC-based method is established to systematically isolate, identify, and quantitate the betalain pigments in the plants of 37
Botond Borcsa et al.
Fitoterapia, 82(3), 365-368 (2010-11-16)
Processed aconite drugs are widely used in Eastern medicine as painkillers and antirheumatic agents. It is known that the traditional processing of aconite drugs increases the amount of lipo-alkaloids. In order to obtain information about the pharmacological potential of these
S K Kundu et al.
Journal of lipid research, 20(7), 825-833 (1979-09-01)
Aminopropyl silica gel was prepared from porous silica gel and was used as a solid support for immunoadsorbent in the purification of anti-glycolipid antibodies. For neutral glycosphingolipids, a carboxyl function was generated by oxidation of the olefinic double bond of
Lian Yih Pong et al.
Chinese medicine, 15, 49-49 (2020-05-30)
Dengue fever is currently endemic in tropical and subtropical countries worldwide and effective drug against DENV infection is still unavailable. Porcupine dates, which are traditionally used to treat dengue fever, might contain potential anti-dengue compounds. Two porcupine dates, black date
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