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Hiroshi Hori et al.
Journal of inorganic biochemistry, 116, 53-54 (2012-09-27)
The effect of the quaternary structure change in deoxy-Hb on the electronic states of the ferrous high-spin heme was studied by multi-frequency electron paramagnetic resonance (MFEPR). We used a single-pass transmission-type EPR at 70-220 GHz and at 1.5K. We compared...
Jing Shi et al.
Journal of food science, 80(6), E1202-E1208 (2015-05-01)
This study investigated the application of Aspergilloglutamic peptidase (AGP) on porcine hemoglobin decolorization. AGP from fungus Aspergillus niger is identified to possess a high preference towards the histidine residues. As histidine residues in hemoglobin are known to coordinate the heme...
Xianbo Lu et al.
Biosensors & bioelectronics, 23(8), 1236-1243 (2007-12-18)
Carbon nanofibers (CNFs), with typical diameters of approximately 80 nm and lengths of the order of micrometers, are extremely attractive in bioanalytical area as they can combine properties of high surface area, non-toxicity, acceptable biocompatibility, ease of fabrication, chemical and...
Bensachee Pattamadilok et al.
Photodermatology, photoimmunology & photomedicine, 28(4), 213-215 (2012-09-29)
Tristimulus colorimetry and diffuse reflectance spectroscopy (DRS) are white-light skin reflectance techniques used to measure the intensity of skin pigmentation. The tristimulus colorimeter is an instrument that measures a perceived color and the DRS instrument measures biological chromophores of the...
Lidai Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(15), 5759-5764 (2013-03-29)
Label-free functional imaging of single red blood cells (RBCs) in vivo holds the key to uncovering the fundamental mechanism of oxygen metabolism in cells. To this end, we developed single-RBC photoacoustic flowoxigraphy (FOG), which can image oxygen delivery from single...
Brendan R Scott et al.
Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology, 24(5), 722-730 (2014-08-16)
This study quantified the inter- and intra-test reliability of telemetric surface electromyography (EMG) and near infrared spectroscopy (NIRS) during resistance exercise. Twelve well-trained young men performed high-intensity back squat exercise (12 sets at 70-90% 1-repetition maximum) on two occasions, during...
Hemoglobin research and the origins of molecular medicine
Schechter AN
Blood, 112(10), 3927-3938 (2008)
Wei Zhang et al.
Colloids and surfaces. B, Biointerfaces, 151, 215-223 (2016-12-26)
In this study, PEGylated graphene oxide (PEG-GO)-hemin composite structure was constructed. Hemin in the form of nanoscaled aggregates were immobilized on PEG-GO sheets by the π-π stacking super-molecular interaction. Via catalyzing the oxidation of chromogenic substrates, we elicited the obtained...
Rebekka Heitmar et al.
Investigative ophthalmology & visual science, 54(4), 2807-2811 (2013-03-16)
To establish the optimal flash settings for retinal vessel oxygen saturation parameters using dual-wavelength imaging in a multiethnic group. Twelve healthy young subjects (mean age 32 years [SD 7]; three Mediterranean, two South Asian, and seven Caucasian individuals) underwent retinal...
Characteristics of bovine hemoglobin as a potential source of hemoglobin-vesicles for an artificial oxygen carrier
Sakai H, et al.
Journal of Biochemistry, 131(4), 611-617 (2002)
Sedef Nehir El et al.
Food & function, 6(7), 2322-2330 (2015-06-16)
The hydrolysis degrees of goat milk and kefir during simulated gastrointestinal digestion and some bioactivities of the resulting peptides after fermentation and digestion were studied. A static in vitro digestion method by the COST FA1005 Action INFOGEST was used and...
Rong Wang et al.
PloS one, 12(2), e0171926-e0171926 (2017-02-17)
The susceptibility of a dietary protein to proteolytic degradation by digestive enzymes, such as gastric pepsin, provides information on the likelihood of systemic exposure to a structurally intact and biologically active macromolecule, thus informing on the safety of proteins for...
Mihaela Balu et al.
Biophysical journal, 104(1), 258-267 (2013-01-22)
We employ a clinical multiphoton microscope to monitor in vivo and noninvasively the changes in reduced nicotinamide adenine dinucleotide (NADH) fluorescence of human epidermal cells during arterial occlusion. We correlate these results with measurements of tissue oxy- and deoxyhemoglobin concentration during...
Urszula Krasuska et al.
Nitric oxide : biology and chemistry, 68, 38-50 (2016-11-29)
Nitric oxide (NO) and polyamines (PAs) belong to plant growth and development regulators. These compounds play a key role in numerous physiological processes e.g. seed germination. Based on the suggestion of overlapping of NO and PAs biosynthetic pathways, we demonstrated...
F C Ezebuo et al.
Indian journal of experimental biology, 50(12), 847-852 (2013-08-31)
Lipoxygenases comprise a family of non-heme iron-containing enzymes that catalyze the stereospecific dioxygenation of polyunsaturated fatty acids with 1, 4-cis-cis-pentadiene structure. Hemoglobin, a heme iron-containing protein has been reported to have lipoxygenase activity but the assay conditions that could enhance...
Sudarshan R Jadcherla et al.
American journal of physiology. Gastrointestinal and liver physiology, 307(1), G41-G49 (2014-05-03)
Central and peripheral neural regulation of swallowing and aerodigestive reflexes is unclear in human neonates. Functional near infrared spectroscopy (NIRS) is a noninvasive method to measure changes in oxyhemoglobin (HbO) and deoxyhemoglobin (HbD). Pharyngoesophageal manometry permits evaluation of aerodigestive reflexes....
Rui Liu et al.
Experimental hematology, 41(7), 656-661 (2013-03-30)
Laser tweezers Raman spectroscopy was used to characterize the oxygenation response of single normal adult, sickle, and cord blood red blood cells (RBCs) to an applied mechanical force. Individual cells were subjected to different forces by varying the laser power...
Edward Slone et al.
Epileptic disorders : international epilepsy journal with videotape, 14(4), 371-378 (2012-12-19)
Growing evidence suggests that focal seizures are preceded by haemodynamic changes. Specifically, changes in cerebral blood flow, blood oxygen level-dependent magnetic resonance imaging, and near-infrared spectroscopy measurements of haemoglobin have been observed in the seizure focus and other brain regions...
Shigeru Obayashi et al.
Neuropsychologia, 51(3), 418-424 (2012-12-04)
The supplementary motor area (SMA) has been regarded as a third speech area. The SMA is anatomically classified into two regions, pre-SMA and SMA proper, but the functional specialization of speech production between the two regions remains unknown. Although word...
Luke J Norbury et al.
Biochimie, 93(3), 604-611 (2010-12-21)
Cathepsin proteases are promising vaccine or drug targets for prophylaxis or therapy against Fasciola parasites which express cathepsin L and B proteases during their development. These proteases are believed to be involved in important functions for the parasite, including excystment...
David Abookasis et al.
Journal of biomedical optics, 18(4), 045003-045003 (2013-04-06)
The authors' aim is to assess and quantitatively measure brain hemodynamic and morphological variations during closed-head injury (CHI) in mice using orthogonal diffuse near-infrared reflectance spectroscopy (o-DRS). CHI is a type of injury to the head that does not penetrate...
Megumi Kobayashi et al.
Neuroreport, 23(17), 984-988 (2012-10-24)
We studied whether 5-month-old to 8-month-old infants process faces in a size-invariant manner by applying the fNIRS-adaptation paradigm used in our previous study. We used near-infrared spectroscopy to measure hemodynamic responses in the temporal regions of infants' brains during the...
Reheman Baikejiang et al.
Journal of biomedical optics, 22(5), 55001-55001 (2017-05-04)
Fluorescence molecular tomography (FMT) is an important in vivo imaging modality to visualize physiological and pathological processes in small animals. However, FMT reconstruction is ill-posed and ill-conditioned due to strong optical scattering in deep tissues, which results in poor spatial...
R Kannan et al.
International journal for numerical methods in biomedical engineering, 28(11), 1093-1106 (2012-10-31)
Near infrared spectroscopy (NIRS) is a technique used to detect and measure changes in the concentrations of oxygenated hemoglobin, deoxygenated hemoglobin, and water in tissues based on the differential absorption, scattering, and refraction of the near infrared light. In this...
A study of the interaction of bovine hemoglobin with synthetic dyes using spectroscopic techniques and molecular docking
Bansal S, et al.
Frontiers in Chemistry, 4(4), 50-50 (2017)
James V Lee et al.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 199(3), 227-238 (2013-01-17)
Songbirds communicate by learned vocalizations with concomitant changes in neurophysiological and genomic activities in discrete parts of the brain. Here, we tested a novel implementation of diffusive optical imaging (also known as diffuse optical imaging, DOI) for monitoring brain physiology...
Guishan Zheng et al.
Biochemistry, 52(47), 8539-8555 (2013-11-15)
The Bohr effect in hemoglobin, which refers to the dependence of the oxygen affinity on the pH, plays an important role in its cooperativity and physiological function. The dominant contribution to the Bohr effect arises from the difference in the...
Lai Truong Phuoc et al.
Dalton transactions (Cambridge, England : 2003), 39(36), 8511-8520 (2010-07-27)
Solid polyenzymatic biocatalysts have been designed by combining two immobilized enzymes, the first one allowing the in situ generation of H(2)O(2) from air and the second one performing an oxidation reaction. The in situ H(2)O(2) generation system is based on...
Jennifer Ehren et al.
PloS one, 4(7), e6313-e6313 (2009-07-22)
Celiac sprue is a life-long disease characterized by an intestinal inflammatory response to dietary gluten. A gluten-free diet is an effective treatment for most patients, but accidental ingestion of gluten is common, leading to incomplete recovery or relapse. Food-grade proteases...
Qing Chen et al.
The Journal of biological chemistry, 291(5), 2371-2378 (2015-12-17)
Diabetes is accompanied by dysregulation of glucose, lipid, and protein metabolism. In recent years, much effort has been spent on understanding how insulin regulates glucose and lipid metabolism, whereas the effect of insulin on protein metabolism has received less attention....
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