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Acid and Base Chart — Table of Acids & Bases
Acid and base chart lists the strength of acids and bases (strongest to weakest) in order. Simple to use laboratory reference chart for scientists, researchers and lab technicians.
Carbodiimide-mediated peptide coupling
Carbodiimide-mediated peptide coupling remains to the most frequently used technique.
Merrifield Peptide Resins
These chloromethylated styrene/divinyl benzene copolymers have been crucial to the development of techniques and technology leading to the routine, convenient synthesis of peptides.
Staudinger Ligation
The reaction between an azide and a phosphine forming an aza-ylide was discovered almost a century ago by Nobel Prize laureate Herrmann Staudinger.
Overcoming Aggregation in Solid-phase Peptide Synthesis
Learn how to overcome aggregation in Solid Phase Peptide Synthesis
Selecting Orthogonal Building Blocks
Novabiochem® product range has one of the largest collections of orthogonally and quasi-orthogonally protected tri-functional amino acids. These derivatives are useful tools for the synthesis of cyclic and branched peptides and peptides carrying side-chain modifications.
Resins for the Fmoc-/tBu-Synthesis of Peptide Acids
The TFA-labile Wang resin is a standard support for batch synthesis of peptide acids following the Fmoc-/tBu-protection scheme.
Glucose in Cell Culture
Importance and uses of glucose in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures
Boc Resin Cleavage and Deprotection
The most popular reagent for cleavage of peptides from Boc-based resins is anhydrous HF. Of all the cleavage procedures HF appears to be the most versatile and least harmful to a wide variety of peptides synthesized on Boc-based resins.
Ferric and Ferrous Iron in Cell Culture
Importance and uses of ferric and ferrous iron in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures
Peptide Coupling Reagents Selection Guide
Novabiochem® offers a large number of coupling reagents for in situ activation. In situ activating reagents are easy to use, fast reacting – even with sterically hindered amino acids, and their use is generally free of side reactions.
Unsaturated Amino Acids
Developments in Chemical Biology research have increased the demand of amino acid building blocks with unsaturated side chains.
Fibroblast Growth Factor Family (FGF)
Fibroblast growth factors in cell culture and various growth factors for your research
Vitamin B6, Pyridoxal and Pyridoxine in Cell Culture
This page segues to comprehensive insights on how Vitamin B6, Pyridoxal and Pyridoxine affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of
Cyclodextrins
Many metabolically important compounds, such as lipid-soluble vitamins and hormones, have very low solubilities in aqueous solutions. Various techniques have been used to solubilize these compounds in tissue culture, cell culture, or other water-based applications.
Fetal Bovine Serum Basics
A lab commodity whose quality may often be taken for granted, serum can make—or break—the outcome of all of your cell-based assays. These 5 key subjects will provide you with a strong educational foundation in the use of sera for
Aerobic Glycolysis and the Warburg Effect
We presents an article about the Warburg effect, and how it is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer
Semi-Bulk Packaging and Dispensing
This technical article discusses large volume solvent containers available with a wide range of dispensing options.
Sure/Seal™ Packaging System
Our Sure/Seal air-sensitive and anhydrous packaging system has been improved to incorporate larger puncture are and new elastomer liner which has greater sealing properties.
Deoxyfluorination with 2-Pyridinesulfonyl Fluoride (PyFluor)
The prevalence of organofluorine compounds in industry and drug design necessitates the ability to introduce C–F bonds to molecules.
Protected Carbohydrate Building Blocks for More Efficient Syntheses
Carbohydrates and their biologically active glycoconjugate analogs are emerging as an important class of biomolecules.
Acid Halogenation Reagents
The generation of an acid chloride is an obvious way to activate the carboxy group for amide bond formation. However, practical application of acid chlorides in peptide synthesis is restricted, because they are prone to side reactions and racemization.
Diels–Alder Reaction
The Diels–Alder reaction is the reaction between a conjugated diene and an alkene (dienophile) to form unsaturated six-membered rings. Since the reaction involves the formation of a cyclic product via a cyclic transition state, it is also referred to as
Biginelli Reaction
The Biginelli Reaction is an acid-catalyzed, three-component reaction between an aldehyde, b-ketoester, and urea that produces tetrahydropyrimidones, which have potential pharmaceutical applications.
Spirocyclic Building Blocks for Scaffold Assembly
Spirocyclic modules containing four-membered rings are currently of growing interest to discovery chemists.
MCAT- 53™ Catalyst for Ruthenium Formation
A recyclable, ligand-free ruthenium catalyst for C–H activation reactions and concomitant C–C bond formation in the presence of water.
Baran Diversinates™
The synthesis of heteroaromatic and aromatic compounds is at the heart of the chemical industry. The ever-growing demand for new chemical entities, coupled with dwindling resources and time constraints allotted to any given research project, a rapid way to diversify
Heck Reaction
The Heck reaction is the palladium catalyzed cross-coupling reaction between alkenes and aryl or vinyl halides (or triflates) to afford substituted alkenes.
Fluorescent Labeling of Peptides
Fluorescent Labeling of Peptides
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