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Reagents for the Mitsunobu Reaction
One of the most powerful and widely used carboncarbon bond forming reactions in organic synthesis is the Mitsunobu reaction.
Stabilized 2-Iodoxybenzoic Acid (SIBX)
IBX is not often used due to the fact that it is an impact-sensitive explosive material, which prevents its shipping and transport, as well as its application in industry.
Ionic Liquids
Ionic Liquids
Catalytic Deprotection—DEPRO™ Catalyst Kit/Catalytic Deprotection
Catalytic Deprotection—DEPRO™ Catalyst Kit/Catalytic Deprotection
New Aromatic Terminal Alkynes
The terminal alkyne functionality has a wide range of applications including most recently the synthesis of spiropyran substituted 2,3-dicyanopyrazines and (±)-asteriscanolide, as well as conversion to enamines using resin-bound 2° amines.
Aldehydes
Aldehydes are perennially attractive building blocks due to their ability to easily react with many nucleophiles.
MeO-BIPHEP
With Ru-complexes of this atropisomeric diphosphine ligand, b-keto esters are reduced to their corresponding b-hydroxy esters in high enantioselectivities.
Crystallization
The elucidation of a macromolecular structure to the atomic level by X-ray or neutron diffraction analysis requires the molecule to be available in the form of relatively large single crystals. Many soluble proteins, membrane proteins, nucleic acids and nucleoprotein complexes
Use of 13C Isotopes in MR Research
Dr. Pratip Bhattacharya, California Institute of Technology. "Stable isotopes have played a very useful role in MR research which involves both MRI and MRS.
Synthia™ Organic Retrosynthesis Software - Resources
Learn more about Synthia™ Organic Retrosynthesis Software and view a list of publications
Spirocyclic Building Blocks for Scaffold Assembly
Spirocyclic modules containing four-membered rings are currently of growing interest to discovery chemists.
Aldol Condensation Reaction
The aldol condensation reaction is an organic reaction introduced by Charles Wurtz, who first prepared the β-hydroxy aldehyde from acetaldehdye in 1872.
Ugi Reaction
The Ugi reaction (Scheme 1) is an isonitrile-based MCR that provides a rapid route for the preparation of a-aminoacyl amide derivatives. The Ugi 4 component condensation of an amine, oxo compound, carboxylic acid and an isocyanide is the most documented
KitAlysis™ High-Throughput Photocatalysis Reaction Screening Kit
The PhotoKitAlysis Reaction Kit was designed to provide the best possible chance of finding good reaction conditions for cross-coupling reactions: pre-weighed base or base solution (provided), 10–20 mmol coupling partner (user supplied), 10 mmol aryl halide substrate (user supplied), Catalysts
Scale-Up Guide: Photocatalysis Reaction
Scale-Up Guide for Photocatalysis Reaction to best enable scale-up success with High-Throughput Screening Kit.
Continuous Flow Synthesis in Microstructured Reactors — A New Way of Thinking Chemical Synthesis
Continuous Flow Synthesis in Microstructured Reactors — A New Way of Thinking Chemical Synthesis
Diethyl Azodicarboxylate (DEAD)
Due to stricter safety regulations, shipment of diethyl azodicarboxylate (DEAD) as a dry reagent is prohibited in the United States. We have achieved full compliance with UN and U.S. DOT safety regulations, and is pleased to offer this extremely versatile
Task-Specific Ionic Liquids
Task-Specific Ionic Liquids (TSILs) for the selective liquid/liquid extraction of heavy metals from aqueous systems were first published by Robin D. Rogers et al. in the year 2001.
Facile and Rapid Chiral Resolution with ChiroSolv Kits
Our company is pleased to partner with ChiroSolve, Inc. to offer, through an exclusive distribution agreement, a series of ready-to-use kits for chiral resolution of racemates.
Benzoylation Reagents
The α-hydroxycarbonyl moiety is an important structural motif in organic synthesis and is present in a substantial number of natural products.
Leighton’s Strained Silacycles
Prof. James L. Leighton has developed constrained five-membered silacycles. These chiral silane Lewis acid reagents are useful chiral catalysts in enantioselective allylations of simple aldehydes or hydrazones for the preparation of chiral carbinols and carbinamines.
Ionic Liquids
Ionic Liquids have experienced a comet-like boost in the last few years. In this edition of ChemFiles, we highlight some current applications of this fascinating class of new materials. We present over 50 new additions to our portfolio of 130+
Diethyl Azodicarboxylate (DEAD)
Diethyl Azodicarboxylate (DEAD)
Imidazolium Derived Reagents
N-Acylimidazoles were recognized in the early 1950s as reactive intermediates suitable for the acylation of amino compounds. The search for better coupling reagents than DCC led to the development of CDI (1,1’-carbonyldiimidazole) and related carbonylimidazoles.
Second-Generation, Designer-Surfactant Kits: Aqueous Reactions in a Box
Reactions once dependent on organic solvents are now being performed in water to eliminate the contributions of organic solvents to chemical waste – and the methodology just became easier with next-generation designer surfactant kits.
N-Heterocyclic Carbene Ligands
A wide range of NHC ligands are commonly available which exhibit high activities.
Functionalized Silica Gels for Organic Synthesis
Functionalized silica gel can be used for the separation and solid-phase extraction (SPE) of sugars, and for the separation of steroids, cholesterol, and triglycerides.
Ketone and Aldehyde α-Oxygenation
The α-hydroxycarbonyl moiety is an important structural motif in organic synthesis and is present in a substantial number of natural products.
BASIONICS™, BASF’s Portfolio of Ionic Liquids
Under the trade name BASIONICS™, BASF offers a portfolio of Ionic Liquids—mainly based on imidazolium cations. The BASIONICS™ portfolio opens up a broad range of basic properties of Ionic Liquids and is classified into standard, acidic, basic, liquid at RT
Hydrogenation Catalysts and Ligands
We are proud to offer new catalysts for hydrogenation through our collaboration with Kanata Chemical Technologies.
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