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Hypoxia Detection Assays
Hypoxia detection assays to measure oxygen levels in both live and fixed cells and tissues.
GABA Transporters
Sigma-Aldrich offers many products related to GABA transporters for your research needs.
Proteinase-Activated Receptors
The search for a functional thrombin receptor, using expression cloning methods, led to the discovery of a G protein-coupled receptor that mediates the actions of thrombin on platelets and endothelial cells.
Cytokine Receptors (Hematopoetin Receptor Family)
We offer many products related to Cytokine Receptors (Hematopoetin Receptor Family) for your research needs.
Serotonin Receptors
We offer many products related to serotonin receptors for your research needs.
NF-κB and Inflammation
Chronic inflammation is an underlying factor in the development and progression of many of the chronic diseases of aging, such as arthritis, atherosclerosis, diabetes, and cancer.
MAPKs
We offers many products related to MAPKs for your research needs.
EGFR
Our company offers many products related to EGFR for your research needs.
Overview of G Protein-coupled Receptors (GPCRs)
We offers many products related to GRKs for your research needs.
Cyclin-dependent Kinases (CDKs)
Cyclin dependent kinases (CDKs) are typical serine/threonine kinases that display the 11 subdomains shared by all kinases. The complete sequence of the Homo sapiens genome shows that among the ~30,000 predicted genes, there are 13 CDKs and 25 cyclins. Eleven
Nitric Oxide Synthases
We offer many products related to nitric oxide synthases for your research needs.
Calcium Channels
We offers many products related to calcium channels for your research needs.
PDGFR
Sigma-Aldrich offers many products related to PDGFR for your research needs.
Directed Evolution
An overview of directed evolution and the methods for generating proteins with optimized or entirely new functions.
ISOGRO® Amplify Recombinant Protein Expression
Our company presents an informative page regarding the use of ISOTEC Stable Isotopes to Amplify Recombinant Protein Expression with ISOGRO.
AMPKs
The AMP-activated protein kinase (AMPK) acts as a sensor of cellular energy status. AMPK exists as heterotrimeric complexes comprising a catalytic α subunit and regulatory β and γ subunits.
Leukotriene Receptors
Sigma-Aldrich offers many products related to leukotriene receptors for your research needs.
Duolink® Proximity Ligation Assay (PLA) Multicolor Kits for Sensitive Multiplex Detection
Duolink® PLA Multicolor technology and the quantification of protein-protein interactions in fixed tissues and cells.
Ca/CaMKs
Our company offers many products related to Ca/CaMKs for your research needs.
Melatonin Receptors
We offer many products related to melatonin receptors for your research needs.
Glutamate Receptors (G Protein Family)
Sigma-Aldrich offers many products related to G-protein family glutamate receptors for your research needs.
FAK
The focal adhesion kinase (FAK) is a cytoplasmic protein tyrosine kinase that distinctly co-localizes with integrins at sites of attachment to their ligands.
Troubleshooting in pGEX Expression Vectors
This page describes troubleshooting strategies for cloning the gene or gene fragment into a pGEX expression vector.
Galanin Receptors
We offer many products related to galanin receptors for your research needs.
Nuclear Receptors (Non-Steroids)
We offer many products related to non-steroid nuclear receptors for your research needs.
Chemokine Receptors
We offer many products related to chemokine receptors for your research needs.
How to Optimize the Duolink® Proximity Ligation Assay
Things to consider for preparation, setup and execution of the Duolink® assay protocol
Duolink® Proximity Ligation Assay Instructional Video
This video will show you step-by-step how to perform a Duolink® PLA experiment with cells on a slide that have already been fixed and permeabilized by the user.
Duolink® PLA Troubleshooting Guide
Support information including tips and tricks, frequently asked questions, and basic troubleshooting.
Studies of Dimerization and Activation of Receptors in the EGFR-Family Using Duolink® Assays
Our aim was to investigate the dimerization and activation pattern of two receptors, EGFR (ErbB1) and HER2 (ErbB2), in the EGFR-family using breast cancer cell lines and selected colon tissues as model systems.
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