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Fibronectin
Fibronectin (FN) is a multifunctional, extracellular plasma glycoprotein produced by hepatocytes that circulates at near micromolar concentration and assembles into extracellular matrix fibrils at cell surfaces along with locally produced cellular FN.
Modulated Gene Expression in 3D Cell Culture: Implications for Drug Discovery
Introduction of the modulation in expression profile for some genes and proteins when comparing 2D versus 3D cell culture conditions.
Extracellular Matrix Proteins and Tools for Cell Culture Optimization
Extracellular matrix proteins such as laminin, collagen, and fibronectin can be used as cell attachment substrates in cell culture.
3D Bioprinting: Bioink Selection Guide
Bioinks selection guide for 3D bioprinting of cells for tissues engineering applications.
What is a Cell Delivery Vehicle?
Cell delivery vehicle are components that can be associated with cells and that allow transplantation in human or animals hosts. These can be natural or synthetic components that will form a gel, embedding the cells.
Using a Novel 3D Perfusion Bioreactor to Culture ß-Actin-RFP Reporter Osteosarcoma
We presents an article on Using a Novel 3D Perfusion Bioreactor to Culture ß-Actin-RFP Reporter Osteosarcoma
Cancer Stem Cell Proliferation in Human Prostate and Breast Cancer Cell Lines Utilizing a New Defined Serum-Free 3D Spheroid Media
Serum-free defined cancer stem cell media used to grow and expand cancer cells in 3D tumorsphere aggregates.
Cell-in-a-Box® Live Cell Encapsulation Nanotechnology
Cell-in-a-Box® technology allows cell encapsulation using biocompatible semipermeable cellulose nanoparticles for cellular therapy and 3D cell culture applications.
Hydrogel Rigidity
The study of matrix stiffness and its effects on cellular behavior has generated a great deal of interest among cell biologists and tissue engineers. The stiffness of a cell substrate can affect cell motility, phagocytosis, and differentiation.
Webinar: Cell Culture in 3D Systems; Moving from a 2D to 3D Environment.
Cell culture in 3D systems: moving from 2D to 3D cell culture? It’s now well accepted by the scientific community that the 3D cell culture condition better recapitulate the in vivo environment and behaviours of cells.
Photocrosslinkable Hydrogels for 3D Cell Culture and Tissue Engineering
Methacrylated collagen, hyaluronic acid, and gelatin (GelMA) hydrogels can be crosslinked with light and photoinitiators (Irgacure/LAP/Ruthenium), used as 3D cell culture scaffolds and bioinks for bioprinting.
MaxGel™ ECM Hydrogel: An In Vitro Human Cell Derived Basement Membrane Extract for 3D Cell Culture Applications
Human cell derived basement membrane extract (BME) hydrogel for 3D cell culture of primary cell, stem cell and xenograph cancer models.
Nanofiber Scaffold Technology Validated in a Historic Human Implant
Technical Article on Nanofiber Scaffold Technology Validated in a Historic Human Implant.
Advanced Cell Culture Technology for Generation of In Vivo-like Tissue Models
Sophisticated models are developing as 3D cell culture technology becomes established and accepted as a means of creating more physiologically relevant cell-based assays.
3D Cell Culture Tools and Techniques
3D cell culture overview. Learn about 2D vs 3D cell culture, advantages of 3D cell culture, and techniques available to develop 3D cell models
3D Organoid Culture: New In Vitro Models of Development and Disease
rganoid culture products to generate tissue and stem cell derived 3D brain, intestinal, gut, lung and cancer tumor organoid models.
Create a 3D kidney nephrotoxicity model on the AIM Biotech 3D cell culture chip
AIM Biotech’s easy-to-use modular platform for conducting 3D cell culture into your research. The AIM Biotech organ-on-a-chip enables you to run simple assays or create more complex microphysiological systems. The versatile platform is suitable for a wide variety of cell...
3D Pluripotent Stem Cells: Simplified Culture and Realistic Differentiation
This white paper illustrates the importance of three-dimensional (3D) cell culture in the production of pluripotent stem cell (PSC)-derived models of embryo development and differentiation. It contains a general overview of embryoid bodies (EBs) and a comparison between the various...
Co-culture of Tumor and Stromal Cells in TrueGel3D™ Hydrogels
TrueGel3D™ synthetic hydrogel can be used to study co-culture of tumor and stromal cells.
HyStem™ Hyaluronic Acid Based Hydrogels for 3D Cell Culture Applications
Hystem 3D hydrogels are based on hyaluronic acid, a major component of the extracellular matrix. 3D cell culture can be done using Hystem hydrogels.
Attachment Factors for 3-Dimensional Cell Culture
Attachment Factors for 3-Dimensional Cell Culture
Three-Dimensional Printing of Tissue Engineering Scaffolds
We will explore the technological advances that have contributed toward the progress of 3DP of tissue engineering scaffolds, current materials used to create 3DP scaffolds, and the challenges that remain.
What is Hyaluronan?
Hyaluronan is a major component of the extracellular matrix. It’s the simplest glycosaminoglycan, and it plays several biological roles.
TrueGel3D™ Hydrogel for 3D Cell Culture
TrueGel3D™ is a synthetic hydrogels platform for 3D cell culture that aim to mimic the natural extracellular environment for more physiological culture conditions
An ECM Mimetic Library for Engineering Surfaces to Direct Cell Surface Receptor Binding Specificity and Signaling
The extracellular (ECM) microenvironment, defined by biochemical cues and physical cues, is a deciding factor in a wide range of cellular processes including cell adhesion, proliferation, differentiation, and expression of phenotype-specific functions. For this reason, engineering the ECM microenvironment provides...
Cultrex® 3-D Culture Matrix™ Basement Membrane Extract Coated 96 Well Plate Protocol
3-D Culture is an innovative approach to modeling the morphological effects of oncogenesis and development using three-dimensional microenvironments.
CytoSoft® Elastic Modulus Plates
CytoSoft® elastic modulus plates are cell culture tools used to accurately analyze the effect of substrate stiffness/rigidity on cell behavior for mechanobiology applications covering a broad physiological range of 0.2 kPA- 64 kPa.
Utilization of TrueGel3D™ Hydrogels to Study Fibroblast Spreading
Fibroblasts that are present in the stroma secrete glycoproteins and polysaccharides to form extracellular matrix. They maintain the structural integrity within the connective tissue and play a key role in cancer, chronic obstructive pulmonary diseases, idiopathic pulmonary fibrosis, scleroderma and...
Tissue-Specific Decellularized Extracellular Matrix (dECM) Hydrogels for Enhanced 3D Cell Cultures
To isolate the native extracellular matrix of a tissue from its inhabiting cells, a decellularization process is employed.
3D Cell Culture with Corning Microplates
Take a deep dive into the world of 3D cell culture courtesy of Corning and understand why the Corning® spheroid microplate can be an asset in the evolution of 3D cell culture.
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