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P Quin et al.
Scientific reports, 5, 16773-16773 (2015-12-01)
Agricultural soils are the primary anthropogenic source of atmospheric nitrous oxide (N2O), contributing to global warming and depletion of stratospheric ozone. Biochar addition has shown potential to lower soil N2O emission, with the mechanisms remaining unclear. We incubated eucalypt biochar
Structural mechanisms of acute VEGF effect on microvessel permeability.
American Journal of Physiology. Heart and Circulatory Physiology, 284, H2124-H2124 (2003)
Flavia Laffleur et al.
Journal of pharmaceutical sciences, 104(7), 2153-2160 (2015-04-23)
It was the aim of this study to evaluate the permeation-enhancing effect of synthesized thiolated hyaluronic acid (HA). HA, a naturally found polysaccharide, was chemically modified with l-cysteine ethyl ether (C) via amide bond formation. In vitro permeation enhancement was
Bin-wu Lin et al.
Investigative ophthalmology & visual science, 56(1), 45-53 (2014-12-11)
To investigate the effect of FK-506 eye drops on Botulinum toxin B (BTX-B)-induced mouse dry eye. Forty-five CBA/J mice were followed up for 4 weeks after treatment with 0.025% FK-506, vehicle or 0.9% saline eye drops 3 days after intralacrimal
Haitham Askar et al.
Journal of dentistry, 43(7), 832-838 (2015-03-15)
Infiltrants are non-filled low-viscosity resins that have been developed to arrest lesion progression by penetrating into the porosities of non-cavitated lesions where they are hardened and arrest lesion progression. The addition of fillers to infiltrant resin might combine the high
Luis Solorio et al.
Journal of pharmaceutical sciences, 104(10), 3471-3480 (2015-07-16)
Phase-sensitive in situ forming implants (ISFI) are a promising platform for the controlled release of therapeutic agents. The simple manufacturing, ease of placement, and diverse payload capacity make these implants an appealing delivery system for a wide range of applications.
Zhiping Cui et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 114, 547-552 (2013-06-25)
A novel fluorescence quenching method for the determination of torasemide (TOR) with some dihalogenated fluorescein dyes as fluorescence probes was developed. In acidulous medium, TOR could interact with some dihalogenated fluorescein dyes such as dichlorofluorescein (DCF), dibromofluorescein (DBF) and diiodofluorescein
Beata Kolesinska et al.
Chemistry & biodiversity, 10(1), 1-38 (2013-01-24)
After a survey of the special role, which the amino acid proline plays in the chemistry of life, the cell-penetrating properties of polycationic proline-containing peptides are discussed, and the widely unknown discovery by the Giralt group (J. Am. Chem. Soc.
Mouming Zhao et al.
Journal of agricultural and food chemistry, 62(31), 7771-7778 (2014-07-17)
This study aimed to explore the potential of polished adlay, brown adlay, adlay bran, and adlay hull to prevent and treat hyperuricemia. Brown adlay extract effectively decreased the serum uric acid levels of oxonate-induced hyperuricemic rats. Free and bound phenolic
Dirk A Ridder et al.
The Journal of experimental medicine, 212(10), 1529-1549 (2015-09-09)
Inactivating mutations of the NF-κB essential modulator (NEMO), a key component of NF-κB signaling, cause the genetic disease incontinentia pigmenti (IP). This leads to severe neurological symptoms, but the mechanisms underlying brain involvement were unclear. Here, we show that selectively
In vitro model of the outer blood-retina barrier.
Steuer H
Brain Research. Brain Research Protocols, 13, 26-26 (2004)
Xian-Fu Zhang et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 113, 92-99 (2013-05-30)
The fluorescence and absorption properties of several xanthene and phthalocyanine dyes were measured in the presence and absence of chemically derived graphene (CDG) sheets. The interaction of pyronine Y (PYY) with graphene sheets was compared with that of rhodamine 6G
Hirohiko Kakizaki et al.
American journal of ophthalmology, 156(5), 1051-1055 (2013-08-27)
To examine movement of the internal canalicular orifice with blinking and lacrimal drainage under endonasal endoscopic observation after dacryocystorhinostomy. Observational anatomic study. Twenty internal canalicular orifices (right 9, left 11) from 15 patients (age range: 44-77 years) who underwent endoscopic
Thao N Yeh et al.
Investigative ophthalmology & visual science, 54(6), 3902-3911 (2013-05-09)
To investigate the effects of 30 nights of overnight orthokeratology (OOK) on corneal epithelial permeability (Pdc) and corneal biomechanical properties. BE Retainer and Paragon CRT lenses were used. Visits were scheduled approximately 4 hours after awakening at baseline and after
Michaela Sieben et al.
Scientific reports, 9(1), 8335-8335 (2019-06-07)
Viscosity is an inherent characteristic of fluids and is therefore an important parameter in many different processes. Current methods to measure viscosity involve direct contact with the liquid sample, which is often undesirable. Here we present a simple, precise and
Anastasia Alex et al.
Investigative ophthalmology & visual science, 54(5), 3325-3332 (2013-04-11)
To identify factors predicting the ocular surface response to experimental desiccating stress. The ocular surfaces of both eyes of 15 normal and 10 dry eye subjects wearing goggles were exposed to a controlled desiccating environment (15%-25% relative humidity and 2-5
Yasuhiro Takahashi et al.
American journal of ophthalmology, 157(4), 807-812 (2014-01-15)
To evaluate efficacy of topical rebamipide for superior limbic keratoconjunctivitis (SLK) in patients with thyroid eye disease. Retrospective, observational case series. Thirty-three eyes from 20 thyroid eye disease patients with SLK who received topical rebamipide (Mucosta ophthalmic suspension unit dose
B Steger et al.
The British journal of ophthalmology, 99(2), 160-165 (2014-08-21)
To first describe in vivo confocal microscopic (IVCM) corneal findings in severe dry eye syndrome due to ocular chronic graft versus host disease (cGvHD) after allogeneic stem cell transplantation. IVCM of the central cornea was performed in 12 prospectively recruited
Fuyuko Takata et al.
Biochemical and biophysical research communications, 433(4), 586-590 (2013-03-26)
Blood-brain barrier (BBB) disruption occurs frequently in CNS diseases and injuries. Few drugs have been developed as therapeutic candidates for facilitating BBB functions. Here, we examined whether metformin up-regulates BBB functions using rat brain microvascular endothelial cells (RBECs). Metformin, concentration-
The determination of the conduction mechanism and optical band gap of fluorescein sodium salt.
Yakuphanoglu F, et al.
Physica B: Condensed Matter, 382(1), 21-25 (2006)
Marisa Tesón et al.
Optometry and vision science : official publication of the American Academy of Optometry, 92(9), e284-e289 (2015-07-24)
To analyze dry eye disease (DED) tests and their consistency in similar nonsymptomatic population samples living in two geographic locations with different climates (Continental vs. Atlantic). This is a pilot study including 14 nonsymptomatic residents from Valladolid (Continental climate, Spain)
Ha-Young Park et al.
Bioscience, biotechnology, and biochemistry, 79(1), 130-137 (2014-09-02)
We investigated the effect of theaflavins (TFs) on membrane barrier of Caco-2 cells. For fluorescein-transport experiments, the apparent permeability (Papp) of fluorescein in Caco-2 cells pretreated with 20 μM TFs were significantly decreased compared with that in untreated cells. Although the
Ran Ran et al.
Acta neurobiologiae experimentalis, 74(4), 405-414 (2015-01-13)
We aim to investigate the changes of The γ-aminobutyric acid (GABA) signals in the adjacent intact dorsal root ganglion (DRG) and the contribution of these changes to the development and maintenance of neuropathic pain (NPP). After establishment of neuropathic pain
Qingyun Yang et al.
Food chemistry, 194, 900-907 (2015-10-17)
In this study, the adsorption and desorption characteristics of six macroporous resins including XAD-7HP, XAD-16, HP-20, HP-2MGL, SP-207 and SP-825 for enrichment of adlay bran free phenolics were studied. XAD-16, SP-207 and SP-825 were chosen for further study due to
Juan L Paris et al.
ACS nano, 9(11), 11023-11033 (2015-10-13)
A new ultrasound-responsive system based on mesoporous silica nanoparticles was developed for biomedical applications, grafting a copolymer on their surface that acts as gatekeeper of the pores. The nanoparticles can be loaded with a cargo at low temperature (4 °C)
Karl-Michael Schebesch et al.
Acta neurochirurgica, 155(4), 693-699 (2013-02-23)
In glioma surgery, the extent of resection (EOR) is one important predictor of progression-free survival. In 2006, fluorescence-guided surgery using 5-aminolevulinic acid (5-ALA) was shown to improve the EOR in malignant gliomas. However, the use of 5-ALA is complex and
Martine Dhilly et al.
Chembiochem : a European journal of chemical biology, 14(6), 759-769 (2013-03-28)
GluN2B-containing NMDA receptors are involved in many important physiological functions and play a pivotal role in mediating pain as well as in several neurodegenerative disorders. We aimed to develop fluorescent probes to target the GluN2B subunit selectively in order to
Kristin M Fischer et al.
American journal of veterinary research, 74(2), 275-280 (2013-02-01)
To determine the effects of topically applied 2% delta-9-tetrahydrocannabinol (THC) ophthalmic solution on aqueous humor flow rate (AHFR) and intraocular pressure (IOP) in clinically normal dogs. 21 clinically normal dogs. A randomized longitudinal crossover design was used. Following acquisition of
John M A Grime et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(38), 14277-14282 (2008-09-13)
The ability to predict and interpret membrane permeation coefficients is of critical importance, particularly because passive transport is crucial for the effective delivery of many pharmaceutical agents to intracellular targets. We present a method for the quantitative measurement of the
Tom De Bruyn et al.
Journal of pharmaceutical sciences, 100(11), 5018-5030 (2011-08-13)
The aim of this study was to characterize the in vitro hepatic uptake kinetics of sodium fluorescein (NaFluo) and identify the transporters involved. NaFluo exhibited saturable uptake kinetics in suspended rat and human hepatocytes as reflected by K(m) values of
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