e6909

" within Papers

Nox2 contributes to age-related oxidative damage to neurons and the cerebral vasculature.

Lampson M Fan et al.

The Journal of clinical investigation, 129(8), 3374-3386 (2019-07-23)

Oxidative stress plays an important role in aging-related neurodegeneration. This study used littermates of WT and Nox2-knockout (Nox2KO) mice plus endothelial cell-specific human Nox2 overexpression-transgenic (HuNox2Tg) mice to investigate Nox2-derived ROS in brain aging. Compared with young WT mice (3-4

Immunohistochemical Characterization and Sensitivity to Human Adenovirus Serotypes 3, 5, and 11p of New Cell Lines Derived from Human Diffuse Grade II to IV Gliomas.

Minna Niittykoski et al.

Translational oncology, 10(5), 772-779 (2017-08-12)

Oncolytic adenoviruses show promise in targeting gliomas because they do not replicate in normal brain cells. However, clinical responses occur only in a subset of patients. One explanation could be the heterogenic expression level of virus receptors. Another contributing factor

Structural Basis for Binding of Fluorescent CMP-Neu5Ac Mimetics to Enzymes of the Human ST8Sia Family.

Gesa Volkers et al.

ACS chemical biology, 13(8), 2320-2328 (2018-07-18)

Polysialyltransferases synthesize polysialic acid on cell surface-expressed glycoconjugates, which is crucial for developing processes and signaling pathways in eukaryotes. Recent advances in cancer research have rendered polysialyltransferases important drug targets because polysialic acid contributes to cancer cell progression, metastasis, and

Using a Three-Dimensional Collagen Matrix to Deliver Respiratory Progenitor Cells to Decellularized Trachea In Vivo.

Nick J I Hamilton et al.

Tissue engineering. Part C, Methods, 25(2), 93-102 (2019-01-17)

This article describes a method for engrafting epithelial progenitor cells to a revascularized scaffold in a protective and supportive collagen-rich environment. This method has the potential to overcome two key limitations of existing grafting techniques as epithelial cells are protected

Cysteine-rich secretory protein 3 plays a role in prostate cancer cell invasion and affects expression of PSA and ANXA1.

Bhakti R Pathak et al.

Molecular and cellular biochemistry, 411(1-2), 11-21 (2015-09-16)

Cysteine-rich secretory protein 3 (CRISP-3) is upregulated in prostate cancer as compared to the normal prostate tissue. Higher expression of CRISP-3 has been linked to poor prognosis and hence it has been thought to act as a prognostic marker for

H55N polymorphism is associated with low citrate synthase activity which regulates lipid metabolism in mouse muscle cells

Gabriel BM, et al.

PLoS ONE, 12(11), e0185789-e0185789 (2017)

Muscle Cell and Tissue: Current Status of Research Field (2018)

Matrigel: basement membrane matrix with biological activity.

Hynda K Kleinman et al.

Seminars in cancer biology, 15(5), 378-386 (2005-06-25)

The basement membrane extracellular matrix contacts epithelial, endothelial, fat and smooth muscle cells. Because this extracellular matrix is so thin, it had been hard to study its composition, structure, and function. An extract of a tumor was found to contain

Knockdown of Thymidine Kinase 1 Suppresses Cell Proliferation, Invasion, Migration, and Epithelial-Mesenchymal Transition in Thyroid Carcinoma Cells.

Chang Liu et al.

Frontiers in oncology, 9, 1475-1475 (2020-02-18)

Patients with advanced thyroid carcinoma have poor prognosis with low overall survival. Unfortunately, the underlying mechanisms of thyroid carcinoma progression remain unclear. The elevated expression of thymidine kinase 1 (TK1) has been implicated in the progression of thyroid carcinoma, while

null

Immunohistochemical Characterization and Sensitivity to Human Adenovirus Serotypes 3, 5, and 11p of New Cell Lines Derived from Human Diffuse Grade II to IV Gliomas

Niittykoski M, et al.

Translational Oncology, 10(5), 772-779 (2017)

Page 1 of 1