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Abel Torres-Espín et al.
Journal of neurotrauma, 32(6), 367-380 (2014-09-10)
Cell therapy for spinal cord injury (SCI) is a promising strategy for clinical application. Mesenchymal stem cells (MSC) have demonstrated beneficial effects following transplantation in animal models of SCI. However, despite the immunoprivilege properties of the MSC, their survival in
Jorge M Santos et al.
Stem cell research & therapy, 6, 90-90 (2015-05-10)
The secretion of trophic factors by mesenchymal stromal cells has gained increased interest given the benefits it may bring to the treatment of a variety of traumatic injuries such as skin wounds. Herein, we report on a three-dimensional culture-based method
Sevelamer crystals in the gastrointestinal tract (GIT): a new entity associated with mucosal injury.
Benjamin J Swanson et al.
The American journal of surgical pathology, 37(11), 1686-1693 (2013-09-26)
We report the first description of sevelamer crystals (Renagel and Renvela, Genzyme; phosphate-lowering agents) in the gastrointestinal tract. We prospectively collected cases with novel, histologically identical crystals from 4 major academic centers over a 1-year period and studied pertinent clinicopathologic
Lukas Horvath et al.
Audiology & neuro-otology, 20(1), 51-61 (2014-11-28)
Activin, a member of the TGF-F superfamily, was found to play an important role in the development, repair and apoptosis of different tissues and organs. Accordingly, activin signaling is involved in the development of the cochlea. Activin binds to its
Vira V Artym et al.
The Journal of cell biology, 208(3), 331-350 (2015-02-04)
Cell interactions with the extracellular matrix (ECM) can regulate multiple cellular activities and the matrix itself in dynamic, bidirectional processes. One such process is local proteolytic modification of the ECM. Invadopodia of tumor cells are actin-rich proteolytic protrusions that locally
Archita Bhattacharjee et al.
Journal of colloid and interface science, 448, 130-139 (2015-03-01)
Green synthesis of SnO2 quantum dots (QDs) was developed by microwave heating method using the amino acids, namely, aspartic and glutamic acid. This method resulted in the formation of spherical SnO2 quantum dots with an average diameter less than the
Joseph Malvehy et al.
JAMA dermatology, 149(9), 1060-1067 (2013-07-19)
In the era of targeted therapy for cancer, translational research identifying molecular targets in melanoma offers novel opportunities for potential new treatments. To describe a method for sampling fresh tissue from primary melanoma and to test whether the area of
Chao Chi et al.
Cell transplantation, 24(11), 2337-2351 (2015-01-07)
Adipose-derived stem cells (ASCs) from subcutaneous and visceral adipose tissues have been studied individually. No studies have compared their abilities in treatment of heart failure. This study was designed to evaluate whether ASCs from the two sources could provide a
Santiago González-López et al.
The journal of adhesive dentistry, 15(5), 481-489 (2013-04-18)
To compare the percentage of collagen exposed in dentin root thirds after two irrigation protocols with manual or rotary instrumentation using two methacrylate resin-based sealers. Forty-eight single-root human teeth were prepared with manual (n = 24) or nickeltitanium ProFile rotary
Ashok Aspatwar et al.
PloS one, 10(7), e0134263-e0134263 (2015-07-29)
Carbonic anhydrase related proteins (CARPs) X and XI are highly conserved across species and are predominantly expressed in neural tissues. The biological role of these proteins is still an enigma. Ray-finned fish have lost the CA11 gene, but instead possess
Bancroft JD
Theory and Practice of Histological Techniques (2008)
Histophatologic Techniques null
Leyuan Xu et al.
Pharmaceutical research, 32(1), 275-285 (2014-07-18)
This work was aimed at developing a semi-interpenetrating network (sIPN) co-electrospun gelatin/insulin fiber scaffold (GIF) formulation for transbuccal insulin delivery. Gelatin was electrospun into fibers and converted into an sIPN following eosin Y-initiated polymerization of polyethylene glycol diacrylate (PEG-DA). The
Xiao Shi et al.
Plant & cell physiology, 56(3), 497-509 (2014-12-19)
Callose plays an important role in pollen development in flowering plants. In rice, 10 genes encoding putative callose synthases have been identified; however, none of them has been functionally characterized. In this study, a rice Glucan Synthase-Like 5 (GSL5) knock-out
Gregory A Johnson et al.
Bioconjugate chemistry, 24(1), 114-123 (2012-12-18)
We test the hypothesis that the antimicrobial peptide (KLAKLAK)(2) enhances the photodynamic activity of the photosensitizer eosin Y upon conjugation. The conjugate eosin-(KLAKLAK)(2) was obtained by solid-phase peptide synthesis. Photoinactivation assays were performed against the Gram-negative bacteria Escherichia coli
Mohammad A Assaggaf et al.
The American journal of pathology, 185(6), 1588-1599 (2015-04-07)
Drug-induced gingival overgrowth is caused by the antiseizure medication phenytoin, calcium channel blockers, and ciclosporin. Characteristics of these drug-induced gingival overgrowth lesions differ. We evaluate the ability of a mouse model to mimic human phenytoin-induced gingival overgrowth and assess the
Kyung-Soo Nam et al.
Oncology letters, 9(1), 483-487 (2014-12-02)
Colorectal adenocarcinoma is the most common type of gastrointestinal cancer. Colon adenocarcinoma is a major health problem worldwide due to the high prevalence and mortality rates associated with the disease. The majority of colorectal carcinomas are adenocarcinomas, which originate from
Oluwole B Akinola et al.
Metabolic brain disease, 30(6), 1531-1536 (2015-08-27)
Diabetes mellitus (DM) is a risk factor for Alzheimer's disease (AD), and several individuals with AD are diabetic. Most non-transgenic animal models of AD make use of oral treatment with aluminium chloride (AlCl(3)) to induce brain lesions pathognomonic of the
Mariko Yokota et al.
Experimental dermatology, 23 Suppl 1, 27-31 (2014-09-23)
Moisturization of the skin plays an important role in maintaining skin homeostasis. Although it is understood that skin dryness initiates the formation of fine wrinkles, there are few objective reports to support that understanding. The purpose of this study was
The effects of simvastatin on hippocampal caspase-3 and Bcl-2 expression following kainate-induced seizures in rats.
Sun J, et al.
International Journal of Molecular Medicine, 30, 739-739 (2012)
Laura Cristina Ceafalan et al.
Anatomical record (Hoboken, N.J. : 2007), 298(11), 1864-1879 (2015-08-12)
Angiogenesis is a key event during tissue regeneration, but the intimate mechanisms controlling this process are still largely unclear. Therefore, the cellular and molecular interplay along normal tissue regeneration should be carefully unveiled. To this matter, we investigated by xMAP
Jie Du et al.
Fish & shellfish immunology, 34(1), 315-323 (2012-11-28)
Freshwater prawn Macrobrachium rosenbergii inoculated with 100 μl novel pathogen spiroplasma strain MR-1008 in logarithmic phase (10(8) spiroplasmas ml(-1)) were examined for alkaline phosphatase (AKP) activity, acid phosphatase (ACP) activity, superoxide dismutase (SOD) activity, catalase (CAT) activity, as well as
Katrein Schaefer et al.
PloS one, 9(12), e114824-e114824 (2014-12-06)
The prevalence of sexually transmitted infections (STIs) is often higher in females than in males. Although the reproductive cycle profoundly modulates local immunity in the female reproductive tract (FRT) system, significant gaps in our knowledge of the immunobiology of the
Nicole M D van der Burg et al.
Journal of controlled release : official journal of the Controlled Release Society, 302, 190-200 (2019-04-04)
In a low inflammatory skin environment, Langerhans cells (LCs) - but not dermal dendritic cells (dDCs) - contribute to the pivotal process of tolerance induction. Thus LCs are a target for specific-tolerance therapies. LCs reside just below the stratum corneum
Lindsey M Ott et al.
Tissue engineering. Part A, 21(17-18), 2390-2403 (2015-06-23)
Tracheal stenosis is a life-threatening disease and current treatments include surgical reconstruction with autologous rib cartilage and the highly complex slide tracheoplasty surgical technique. We propose using a sustainable implant, composed of a tunable, fibrous scaffold with encapsulated chondrogenic growth
Nathan M Long et al.
PloS one, 10(4), e0122152-e0122152 (2015-04-16)
Maternal obesity in women is increasing worldwide. The objective of this study was to evaluate differences in adipose tissue metabolism and function in adult male offspring from obese and control fed mothers subjected to an ad libitum feeding challenge. We
Staci L Solin et al.
PloS one, 9(12), e114888-e114888 (2014-12-09)
In this study we describe the molecular and cellular characterization of a zebrafish mutant that develops tumors in the optic pathway. Heterozygous Tg(flk1:RFP)is18 transgenic adults develop tumors of the retina, optic nerve and optic tract. Molecular and genetic mapping demonstrate
Fenghong Wu et al.
Archives of environmental & occupational health, 68(3), 161-165 (2013-04-10)
Ammonium perchlorate (AP) is a kind of inorganic chemical. To evaluate the potential pulmonary fibrosis caused by occupational exposure to this compound, 25 male rabbits were randomly allocated into 5 groups to receive AP or bleomycin or saline by intratracheal
Jaideep Honavar et al.
American journal of physiology. Lung cellular and molecular physiology, 307(11), L888-L894 (2014-10-19)
Exposure to relatively high levels of chlorine (Cl₂) gas can occur in mass-casualty scenarios associated with accidental or intentional release. Recent studies have shown a significant postexposure injury phase to the airways, pulmonary, and systemic vasculatures mediated in part by
Lucy A Walton et al.
Scientific reports, 5, 10074-10074 (2015-05-16)
Characterisation and quantification of tissue structures is limited by sectioning-induced artefacts and by the difficulties of visualising and segmenting 3D volumes. Here we demonstrate that, even in the absence of X-ray contrast agents, X-ray computed microtomography (microCT) and nanotomography (nanoCT)
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