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Vincent M Vacca et al.
Nursing, 43(11), 16-17 (2013-10-22)
Tonia Zangari et al.
Infection and immunity, 81(5), 1562-1574 (2013-02-27)
In May 2011, a large food-borne outbreak was traced to an unusual O104:H4 enteroaggregative Escherichia coli (EAEC) strain that produced Shiga toxin (Stx) type 2 (Stx2). We developed a mouse model to study the pathogenesis and treatment for this strain
Sheetal R Modi et al.
Nature, 499(7457), 219-222 (2013-06-12)
The mammalian gut ecosystem has considerable influence on host physiology, but the mechanisms that sustain this complex environment in the face of different stresses remain obscure. Perturbations to the gut ecosystem, such as through antibiotic treatment or diet, are at
An unusual presentation of altered mental status after orthotopic liver transplantation: Listeria brain abscess.
Jennifer Tseng et al.
Transplantation, 95(12), e72-e73 (2013-06-19)
Rebecca E Schmitt et al.
Alcoholism, clinical and experimental research, 43(9), 1872-1886 (2019-06-27)
Self-Rating of the Effects of Alcohol (SRE) measures level of response to ethanol (EtOH) in humans. Interestingly, there is a positive relationship between the SRE and risk for abusing alcohol, suggesting mechanistic connections between SRE and alcohol abuse. To identify
Marta Putrinš et al.
Infection and immunity, 83(3), 1056-1067 (2015-01-07)
Uropathogenic strains of Escherichia coli (UPEC) are the major cause of bacteremic urinary tract infections. Survival in the bloodstream is associated with different mechanisms that help to resist serum complement-mediated killing. While the phenotypic heterogeneity of bacteria has been shown
Reply to Gelfand et al and Solla.
Nuria Fernández-Hidalgo et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 57(5), 768-770 (2013-05-25)
Oxana Dmitrieva-Posocco et al.
Immunity, 50(1), 166-180 (2019-01-17)
Chronic inflammation drives the progression of colorectal cancer (CRC). Increased expression of interleukin (IL)-17A is associated with poor prognosis, and IL-17A blockade curbs tumor progression in preclinical models of CRC. Here we examined the impact of IL-1 signaling, a key
Jong Seop Sim et al.
Journal of Korean medical science, 27(12), 1598-1600 (2012-12-21)
Selective intestinal decontamination (SID) with norfloxacin has been widely used for the prophylaxis of spontaneous bacterial peritonitis (SBP) because of a high recurrence rate and preventive effect of SID for SBP. However, it does select resistant gut flora and may
Tarayn Fairlie et al.
Obstetrics and gynecology, 121(3), 570-577 (2013-05-03)
To estimate the effectiveness against early-onset group B streptococcal (GBS) disease of intrapartum antibiotic prophylaxis among term and preterm deliveries, deliveries with fewer than 4 hours of antibiotics, and deliveries receiving clindamycin regimens. We performed a secondary analysis of the
Ziad Al Nabhani et al.
Immunity, 50(5), 1276-1288 (2019-03-25)
Microbes colonize all body surfaces at birth and participate in the development of the immune system. In newborn mammals, the intestinal microbiota is first shaped by the dietary and immunological components of milk and then changes upon the introduction of
Jianhua Yin et al.
PloS one, 8(3), e60460-e60460 (2013-04-05)
Shewanella oneidensis is a facultative anaerobic γ-proteobacterium possessing remarkably diverse respiratory capacities for reducing various organic and inorganic substrates. As a veteran research model for investigating redox transformations of environmental contaminants the bacterium is well known to be a naturally
Nuria Fernández-Hidalgo et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 56(9), 1261-1268 (2013-02-09)
The aim of this study was to compare the effectiveness of the ampicillin plus ceftriaxone (AC) and ampicillin plus gentamicin (AG) combinations for treating Enterococcus faecalis infective endocarditis (EFIE). An observational, nonrandomized, comparative multicenter cohort study was conducted at 17
Zhiyuan You et al.
Autophagy, 15(8), 1309-1321 (2019-02-16)
TP53INP2/DOR (tumor protein p53-inducible nuclear protein 2) contributes to mammalian macroautophagy/autophagy by carrying nuclear deacetylated MAP1LC3/LC3 to the cytoplasm. Here, we report that in the cytoplasm, TP53INP2 further functions in autophagosome biogenesis by promoting LC3B-ATG7 interaction. Cytoplasmic expression of the
Jessina C McGregor et al.
BMC family practice, 14, 25-25 (2013-02-26)
Urinary tract infections (UTIs) are one of the most common infections treated in ambulatory care settings, however the epidemiology differs by age and sex. The incidence of UTI is far greater in females than males, and infection in pediatric patients
Bacterial endocarditis following lithotripsy: an unusual complication caused by a non-invasive procedure.
Alessandra Soriano et al.
The Israel Medical Association journal : IMAJ, 16(12), 803-804 (2015-01-30)
Chishih Chu et al.
Foodborne pathogens and disease, 10(3), 256-262 (2013-03-16)
A total of 117 mastitis-associated Staphylococcus aureus isolates from cow, goat, and human patients were analyzed for differences in antibiotic susceptibility, virulence genes, and genotypes using accessory gene regulator (agr) typing, pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST).
Robin A Sorg et al.
Nature communications, 6, 8773-8773 (2015-10-31)
The human pathogen Streptococcus pneumoniae shows alarming rates of antibiotic resistance emergence. The basic requirements for de novo resistance emergence are poorly understood in the pneumococcus. Here we systematically analyse the impact of antibiotics on S. pneumoniae at concentrations that
Xiao Zhu et al.
Toxicology, 321, 62-72 (2014-04-12)
Drug-induced liver injury (DILI) is one of the most common drug-induced adverse events (AEs) leading to life-threatening conditions such as acute liver failure. It has also been recognized as the single most common cause of safety-related post-market withdrawals or warnings.
Benjamin Ezraty et al.
Science (New York, N.Y.), 340(6140), 1583-1587 (2013-07-03)
All bactericidal antibiotics were recently proposed to kill by inducing reactive oxygen species (ROS) production, causing destabilization of iron-sulfur (Fe-S) clusters and generating Fenton chemistry. We find that the ROS response is dispensable upon treatment with bactericidal antibiotics. Furthermore, we
Editorial Commentary: Enterococcus faecalis infective endocarditis: is it time to abandon aminoglycosides?
Jose M Munita et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 56(9), 1269-1272 (2013-02-09)
Combination therapy for enterococcal endocarditis.
Michael S Gelfand et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 57(5), 767-767 (2013-05-25)
Letian Xu et al.
Microbial ecology, 70(4), 1012-1023 (2015-05-20)
Bark beetles are the most important mortality agent in coniferous forests, and pheromones play important roles in their management. Dendroctonus valens LeConte was introduced from North America to China and has killed millions of healthy pines there. Trapping with semiochemicals
Yuraporn Sahasakul et al.
The British journal of nutrition, 112(3), 408-415 (2014-06-17)
Lactobacilli are indigenous microbes of the stomach of rodents, with much lower numbers being present in mice fed a purified diet than in those fed a non-purified diet. We postulated that gastric emptying (GE) is responsible for the different colonisation
Nishant Patel et al.
Connecticut medicine, 77(1), 35-41 (2013-02-23)
The risk of central line associated blood stream infections (CLABSI) related to cooling catheters used for therapeutic hypothermia (TH) is unclear. We performed a retrospective analysis on 131 cardiac arrest survivors between 2007 and 2010, who underwent TH by femorally
Sean Ekins et al.
Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17)
Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predictive in vivo, in vitro, and in silico models to identify compounds
Shawn French et al.
Cell systems, 7(3), 339-346 (2018-09-03)
Open-source electronics are becoming more prevalent in biological sciences, enabling novel and unique means of data acquisition. Here, we present 3D-printed, open-source tools to acquire fluorescence phenotypes with high temporal resolution. Printed fluorescence imaging boxes (PFIboxes) cost approximately 200 US dollars
Danielle M Silva et al.
Anais da Academia Brasileira de Ciencias, 91(2), e20180117-e20180117 (2019-05-16)
One manner in which plant-derived compounds exert their antibiotic potential is the synergism, a positive interaction between two compounds. Studies indicate that the use of plant extracts combined with antimicrobials may promote a significant reduction of the minimum inhibitory concentrations
Senait Assefa et al.
Gut pathogens, 7, 35-35 (2016-01-01)
Recent research suggests integration of the intestinal microbiota in gut-brain communication which could lead to new approaches to treat neurological disorders. The highly social prairie voles are an excellent model system to study the effects of environmental factors on social
Yuanyuan Liu et al.
Science (New York, N.Y.), 339(6124), 1210-1213 (2013-03-09)
Recent observations have suggested that classic antibiotics kill bacteria by stimulating the formation of reactive oxygen species (ROS). If true, this notion might guide new strategies to improve antibiotic efficacy. In this study, the model was directly tested. Contrary to
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