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Ventricular dysfunction and necrosis produced by adrenochrome metabolite of epinephrine: relation to pathogenesis of catecholamine cardiomyopathy.
Yates JC, et al.
American Heart Journal, 102, 210-210 (1981)
John A Mills
History of psychiatry, 18(70 Pt 2), 179-201 (2008-07-02)
The government of the Saskatchewan Co-Operative Commonwealth Federation, when elected in 1944, established programmes for the state-funded care of all those suffering from mental illness. It enacted legislation covering the care and treatment of the mentally ill and created a
Towards an adrenaline biosensor based on substrate recycling amplification in combination with an enzyme logic gate.
Molinnus D, et al.
Sensors and Actuators B, Chemical, 237, 190-195 (2016)
Zhimin Tao et al.
Langmuir : the ACS journal of surfaces and colloids, 25(17), 10183-10188 (2009-05-27)
We have measured the influence of mesoporous silica (MCM-41 and SBA-15) nanoparticles and dense silica nanoparticles on epinephrine oxidation, a pH-dependent reaction, whose rate is small in acidic or neutral solutions but much greater at higher pH. The reaction was
Laure-Estelle Cassagnes et al.
Free radical biology & medicine, 120, 56-61 (2018-03-13)
There is increasing evidence that oxidative stress is involved in the etiology and pathogenesis of neurodegenerative disorders. Overproduction of reactive oxygen species (ROS) is due in part to the reactivity of catecholamines, such as dopamine, adrenaline, and noradrenaline. These molecules
Diseases of the nervous system, 25, 173-178 (1964-03-01)
Xiaojuan Gan et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 97, 161-166 (2012-07-04)
A sensitive, simple and selective spectrofluorimetric method for the reaction of carbazochrome (CBZC) and Eosin Y (EY) or Phloxine B (PB) in acidic medium is developed for the determination of carbazochrome in biological fluids, which gives a highly fluorescent derivative
John A Mills
History of psychology, 13(2), 178-195 (2010-06-11)
Working in a psychiatrically innovative environment created by the Government of Saskatchewan, Canada, Abram Hoffer and Humphry F. Osmond enunciated the adrenochrome hypothesis for the biogenesis of schizophrenia in 1952, slightly later proposing and, apparently, demonstrating, in a double-blind study
Min Song et al.
Biomedical chromatography : BMC, 24(9), 990-999 (2010-02-11)
A highly selective and sensitive liquid chromatography coupled with atmospheric pressure chemical ionization tandem mass spectrometry (LC-APCI-MS-MS) was developed and validated for the quantitation and pharmacokinetic study of carbazochrome sodium sulfonate in human plasma. Protein precipitation with 14% perchloric acid
Christopher D Bahl et al.
Angewandte Chemie (International ed. in English), 54(34), 9881-9885 (2015-07-03)
Opportunistic pathogens exploit diverse strategies to sabotage host defenses. Pseudomonas aeruginosa secretes the CFTR inhibitory factor Cif and thus triggers loss of CFTR, an ion channel required for airway mucociliary defense. However, the mechanism of action of Cif has remained
T V Sirota
Biomeditsinskaia khimiia, 58(1), 77-87 (2012-05-31)
The reaction of adrenaline autoxidation in an alkaline buffer with the formation of superoxide radicals and the product of its oxidation, adrenochrome, which models the quinoid pathway of adrenaline conversion in the body, is accompanied by oxygen consumption. This reaction
Cardiotoxicity of adrenochrome in isolated rabbit hearts assessed by epicardial NADH fluorescence.
Rump AF, et al.
Archives of Toxicology, 68, 571-571 (1994)
Urszula Krasuska et al.
Nitric oxide : biology and chemistry, 68, 56-67 (2016-11-05)
A non-protein amino acid (NPAA) - meta-Tyrosine (m-Tyr), is a harmful compound produced by fescue roots. Young (3-4 days old) tomato (Solanum lycopersicum L.) seedlings were supplemented for 24-72 h with m-Tyr (50 or 250 μM) inhibiting root growth by 50 or
Peihan Orestes et al.
The Journal of physiology, 589(Pt 1), 135-148 (2010-11-10)
Nitrous oxide (N2O, laughing gas) has been used as an anaesthetic and analgesic for almost two centuries, but its cellular targets remain unclear. Here, we present a molecular mechanism of nitrous oxide's selective inhibition of CaV3.2 low-voltage-activated (T-type) calcium channels
Yue Fu et al.
The Journal of biological chemistry, 283(35), 23829-23835 (2008-06-27)
The functions of quinone reductase 2 have eluded researchers for decades even though a genetic polymorphism is associated with various neurological disorders. Employing enzymatic studies using adrenochrome as a substrate, we show that quinone reductase 2 is specific for the
Effect of Bacillus coagulans and B. firmus incorporated probiotic diet on Superoxide dismutase activity and catalase activity in Penaeus monodon.
Raghu P, et al.
World Scientific News, 44, 224-224 (2016)
Tohru Takahashi et al.
General hospital psychiatry, 34(6), 703-703 (2012-04-21)
We report the case of a 47-year-old man with depression who developed acute dyspnea, hypoxemia, and mild hemoptysis after electroconvulsive therapy (ECT). Intravenous carbazochrome sodium sulfate hydrate as a hemostatic drug (100 mg/day) was prescribed for 2 days. On the
I S Severina et al.
Biomeditsinskaia khimiia, 54(6), 679-686 (2009-02-12)
The influence of adrenochrome and YC-1 on spermine NONO-induced activation of human soluble guanylyl cyclase was investigated. Adrenochrome (0.1-10 microM) had no effect on the basal activity, but it potentiated in concentration-dependent manner the spermine NONO-induced activation of this enzyme.
Adrenochrome and related oxidative metabolites of catecholamines: effects on dopamine neurons and receptor binding profiles.
John L Krstenansky et al.
Schizophrenia research, 133(1-3), 264-265 (2011-09-13)
Dongchun Liu et al.
International journal of pharmaceutics, 307(2), 300-307 (2005-11-29)
A series of poly(ethyl acrylate (EA)/methyl methacrylate (MMA)/2-hydroxyethyl methacrylate (HEMA)) lattices were synthesized to prepare short-term delayed-release microcapsules by employing the Wurster coating process. Latex with a HEMA molar fraction exceeding 60% could not be synthesized as an aqueous suspension
Tomohiro Onodera et al.
The Journal of arthroplasty, 27(1), 105-108 (2011-03-26)
The aim of this randomized prospective study was to clarify risks associated with a drain-clamping method using tranexamic acid and carbazochrome sodium sulfonate hydrate after total knee arthroplasty (TKA). Subjects comprised 100 patients scheduled to undergo TKA, randomized into 2
Maria Luisa Genova et al.
Archives of biochemistry and biophysics, 447(2), 167-173 (2006-02-21)
Complex I in bovine heart submitochondrial particles catalyses the NADH-supported generation of superoxide anion; adrenaline is oxidised by superoxide to adrenochrome that, on its hand, is reduced by Complex I, thus establishing a redox cycle that amplifies the superoxide production.
Cecilia I Perez-Moreno et al.
The Canadian veterinary journal = La revue veterinaire canadienne, 50(8), 821-827 (2009-11-03)
The objective was to quantify the effect of furosemide and carbazochrome on exercise-induced pulmonary hemorrhage (EIPH) in Standardbred horses using red blood cell count and hemoglobin concentration in bronchoalveolar lavage (BAL) fluid. Six healthy Standardbred horses with prior evidence of
Successful treatment of schizophrenia requires optimal daily doses of vitamin B3.
Abram Hoffer et al.
Alternative medicine review : a journal of clinical therapeutic, 13(4), 287-291 (2009-02-26)
Dengue fever.
Marissa Alejandria
Clinical evidence, (13)(13), 887-895 (2005-09-02)
Adrenochrome-induced coronary artery constriction in the rat heart.
Karmazyn M, et al.
Journal of Pharmacology and Experimental Therapeutics, 219, 225-225 (1981)
Angela María Gutiérrez-Alvarez et al.
Revista cubana de medicina tropical, 58(3), 212-218 (2006-09-01)
Electronic database Medline, Embase, Cochrane Library and Lilacs were used to retrieve the clinical trials that will evaluate the various therapeutical options available for management of hemorrhagic dengue. Eight clinical studies were included. Supportive care and symptomatic treatment through hydration
Samuel Bernardo-Bermejo et al.
Journal of chromatography. A, 1596, 124-133 (2019-03-18)
Diabetes mellitus is a major health concern nowadays. It is estimated that 40% of diabetics are affected by diabetic nephropathy, one of the complications derived from high glucose blood levels which can lead to chronic loss of kidney function. It
Adrenochrome and related compounds.
R A Heacock et al.
Progress in medicinal chemistry, 9(2), 275-339 (1972-01-01)
The oxidative metabolism of catecholamines in the brain: a review.
Smythies J and Galzigna L
Biochimica et Biophysica Acta, 1380, 159-159 (1998)
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