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Yong-Qiu Zheng et al.
Acta pharmacologica Sinica, 30(7), 919-927 (2009-07-04)
To test the role of the Beclin 1-dependent autophagy pathway in brain damage during cerebral ischemia. Focal cerebral ischemia was established in rats using a middle cerebral artery occlusion (MCAO) model. A lentiviral vector-associated RNA interference (RNAi) system was stereotaxically...
Priya Duggal et al.
Annals of internal medicine, 158(4), 235-245 (2013-02-20)
Chinese translation Hepatitis C virus (HCV) infections occur worldwide and either spontaneously resolve or persist and markedly increase the person's lifetime risk for cirrhosis and hepatocellular carcinoma. Although HCV persistence occurs more often in persons of African ancestry and persons...
M E Pape et al.
Journal of lipid research, 36(4), 823-838 (1995-04-01)
A human cDNA clone (K1) was recently isolated that encodes functional acyl-CoA:cholesterol acyltransferase (ACAT) protein (Chang et al. J. Biol. Chem. 1993. 268: 20747-20755). We used the K1 clone to screen a rabbit liver cDNA library and isolated a 919...
Anna Frisinghelli et al.
Clinical drug investigation, 27(9), 591-604 (2007-08-21)
HMG-CoA reductase inhibitors (statins) are the drugs of first choice for treating hypercholesterolaemia in order to prevent or slow the progression of coronary heart disease (CHD). Statins generally reduce the risk of CHD morbidity or mortality by about 30%. Lovastatin...
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