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F Sezer Senol et al.
Pharmaceutical biology, 52(7), 873-882 (2014-06-13)
Scorzonera L. species (Asteraceae) are edible and as medicinal plants are used for various purposed in folk medicine. The methanol extracts of the aerial parts and roots from 27 Scorzonera taxa were investigated for their possible neurobiological effects. Inhibitory potential
C Flavia Massaro et al.
Journal of agricultural and food chemistry, 62(50), 12209-12217 (2014-11-26)
Australian stingless bee honeys have been shown to exert antioxidant and in vitro antimicrobial properties; however their bioactive factors remained unidentified. This study investigated the antibacterial properties of phenolic extracts from Tetragonula carbonaria honeys. Honeys were harvested from beehives in
Alessandro Paolini et al.
International journal of oncology, 46(4), 1491-1497 (2015-02-04)
Glioblastoma multiforme (GBM) is the most malignant primary brain tumor in adulthood, characterized by very high recurrence. Following the limited results for conventional therapies, novel therapeutic agents are under investigation. Among the putative new molecules, gallic acid (GA) represents a
Jung-Hoon Kim et al.
Archives of pharmacal research, 38(1), 52-62 (2014-03-13)
This study was designed for quality assessment of Gyejibokryeong-hwan (GBH) preparations using the simultaneous determination of 11 marker compounds such as gallic acid, oxypaeoniflorin, amygdalin, albiflorin, paeoniflorin, benzoic acid, coumarin, cinnamic acid, benzoylpaeoniflorin, cinnamaldehyde, and paeonol using HPLC-PDA and chemometric
Kuo-Ching Liu et al.
Environmental toxicology, 28(10), 579-587 (2011-09-03)
Our earlier studies have demonstrated that gallic acid (GA) induced cytotoxic effects including induction of apoptosis and DNA damage and inhibited the cell migration and invasion in human cancer cells. However, GA-affected DNA damage and repair gene expressions in human
Fei-Fei Lin et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(10), 1518-1520 (2013-08-21)
To develop an HPLC method for simultaneous determination of gallic acid and hesperidin in Xiaogu capsule, in order to provide a simple, rapid and accurate method for quality control of the compound preparation of traditional Chinese medicine. Xiaogu capsule was
Kalathookunnel Antony Antu et al.
PloS one, 9(9), e105829-e105829 (2014-09-04)
The study is designed to find out the biochemical basis of antidiabetic property of Symplocos cochinchinensis (SC), the main ingredient of 'Nisakathakadi' an Ayurvedic decoction for diabetes. Since diabetes is a multifactorial disease, ethanolic extract of the bark (SCE) and
Constant Anatole Pieme et al.
Biological research, 47, 54-54 (2015-02-28)
Zanthoxylum heitzii is a spice used to prepare several dishes and to treat tumors, syphilis, malaria, cardiac palpitations, urogenital infections in the west region of Cameroon, but the antitumor mechanisms and chemical composition are not yet investigated. This study was
Dong Ho Suh et al.
Journal of agricultural and food chemistry, 62(34), 8764-8771 (2014-08-08)
Metabolite profiling of red and white pitayas (Hylocereus polyrhizus and Hylocereus undatus) was performed using gas chromatography-time-of-flight-mass spectrometry and ultraperformance liquid chromatography-quadrupole-time-of-flight-mass spectrometry with multivariate analysis. Different species and parts of pitayas (red peel, RP; white peel, WP; red flesh
I J Kade et al.
Neurochemical research, 38(4), 761-771 (2013-02-06)
Redox imbalances and altered signaling processes in the brain are characteristic features of diabetic complications. Hence, the present study therefore sought to evaluate the effect of gallic acid (GA) on disturbed redox systems and activity of neurotransmission signaling dependent enzymes
Vivian Caetano Bochi et al.
Food chemistry, 176, 234-243 (2015-01-28)
Ceylon gooseberry is a deep-purple exotic berry that is being produced in Brazil with great market potential. This work aimed to determine major phenolic compounds in this specie by HPLC-PDA-ESI/MS. Samples were collected in two different seasons. Pulp and skin
Farid Dahmoune et al.
Food chemistry, 166, 585-595 (2014-07-24)
Phytochemicals, such as phenolic compounds, are of great interest due to their health-benefitting antioxidant properties and possible protection against inflammation, cardiovascular diseases and certain types of cancer. Maximum retention of these phytochemicals during extraction requires optimised process parameter conditions. A
Lorena Trigueros et al.
Journal of agricultural and food chemistry, 62(27), 6417-6425 (2014-06-19)
Pomegranate juice (PGJ) is rich in phenolics which are potent antioxidants but also prone to interact with proteins. A yogurt rich in PGJ (40%) made from arils was elaborated (PGY) to determine the antioxidant activity and to estimate the phenolics-proteins
Chin-Yin Lin et al.
Molecular medicine reports, 10(6), 3334-3342 (2014-09-23)
Koelreuteria formosana ethanolic extract (KFEE) is obtained from natural plants that are endemic to Taiwan. In a previous study, it was demonstrated that KFEE inhibited low-density lipoprotein (LDL) and prevented oxidized LDL‑induced apoptosis in endothelial cells. In the present study
O Kenny et al.
Food chemistry, 161, 79-86 (2014-05-20)
Antimicrobial properties of ethanol and water extracts from eight Asteraceae species were investigated against three Gram positive (Staphylococcus aureus, MRSA and Bacillus cereus) and two Gram negative (Escherichia coli and Salmonella typhimurium) bacterial strains. Ethanol extracts from Centaurea scabiosa, Arctium
Mohamed-Salah Abaza et al.
Pharmaceutical biology, 51(9), 1110-1124 (2013-06-12)
For its variety of biological activities, Tamarix aucheriana (Decne.) Baum. (Tamaricaceae) has an extensive history as a traditional Arab medicine. Antimitogenic and chemo-sensitizing activities of syringic acid (SA) were studied against human colorectal cancer. Chromatographic and spectral data were used
Roopali N Bhoite et al.
Preparative biochemistry & biotechnology, 43(4), 350-363 (2013-03-08)
Gallic acid (3,4,5-trihydroxybenzoic acid) was produced by microbial biotransformation of coffee pulp tannins by Penicillium verrucosum. Gallic acid production was optimized using response surface methodology (RSM) based on central composite rotatable design. Process parameters such as pH, moisture, and fermentation
Fatih Mehmet Yılmaz et al.
Journal of food science and technology, 52(5), 2851-2859 (2015-04-22)
There is an increasing interest to bio-components obtained from fruit & vegetable wastes. Anthocyanin is one of the components regained from fruits especially from red ones. Sour cherry is considered as industrial fruit since most of the grown fruit is
Marlena K Sheridan et al.
Food chemistry, 177, 17-22 (2015-02-11)
Wine tannins undergo modifications during fermentation and storage that can decrease their perceived astringency and increase color stability. Acetaldehyde acts as a bridging compound to form modified tannins and polymeric pigments that are less likely to form tannin-protein complexes than
Su Yun Lee et al.
Food chemistry, 165, 157-166 (2014-07-21)
In this study, a comprehensive metabolite profile analysis of doenjang, a fermented soybean paste, at various steps of its industrial 5-step production process was conducted, by combining gas and liquid chromatography-mass spectrometry techniques with multivariate analysis. From the partial least
Wojciech Ostrowski et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 967, 21-27 (2014-07-27)
Liquid chromatography coupled to mass spectrometry (MS) with electrospray ionization (ESI) is one of analytical techniques to obtain accurate results of low molecular weight aromatic compounds in biological samples of different origin. The interpretations of mass spectra of these aromatic
Xu Zhao et al.
Journal of agricultural and food chemistry, 62(26), 6227-6235 (2014-06-17)
The variations in antioxidant activity and concentration of functional components in the ethanol extracts of lotus seeds and rhizomes based on the growing region and dryness were investigated. Free radical scavenging activity, total phenolic and flavonoid content, and concentration of
Shufang Wang et al.
Journal of separation science, 37(14), 1748-1761 (2014-04-29)
In this work, the chemical constituents in Da-Huang-Gan-Cao-Tang, a traditional Chinese formula, were studied by liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry and liquid chromatography coupled with ion trap mass spectrometry for the first time. Among the 146
Junliang Yao et al.
Biochemistry, 52(11), 1893-1902 (2013-02-28)
Inhibition of anomalous aggregation of tau protein would be an attractive therapeutic target for Alzheimer's disease (AD). In this study, tannic acid (TA), a polymeric plant polyphenol, and its monomer, gallic acid (GA), were introduced as the references to afford
Danning Zhang et al.
Environmental science & technology, 48(21), 12645-12653 (2014-10-15)
The formation of reactive oxygen species (ROS) from effluent organic matter (EfOM) was investigated under simulated solar irradiation. In this study, EfOM was isolated into three different fractions based on hydrophobicity. The productivity of ROS in EfOM was measured and
Irwin R A Menezes et al.
Pharmaceutical biology, 53(2), 185-191 (2014-09-27)
Murraya paniculata (Linn) JACK (Rutaceae) is used in traditional medicine in the treatment of diabetes, inflammation, and microbial disorders. This study determined the polyphenol composition and antimicrobial and acute toxicological activity of the hydroethanolic extract of M. paniculata leaves (EEMp).
B M Hausen et al.
Contact dermatitis, 26(4), 253-258 (1992-04-01)
8 alkyl gallates, including the widely used antioxidants propyl, octyl, and dodecyl (= lauryl) gallate, have been subjected to experimental sensitization in guinea pigs. Using a modern sensitization procedure, the results showed that all gallates are moderate to strong contact
Snezana Agatonovic-Kustrin et al.
Journal of pharmaceutical and biomedical analysis, 102, 93-99 (2014-09-26)
Health benefits of wine, especially with red wine, have been linked to the presence of a wide range of phenolic antioxidants. Thus, the aim of this study was to develop a simple, high performance thin layer chromatographic (HPTLC) method combined
J P Dzoyem et al.
Journal of ethnopharmacology, 160, 194-201 (2014-12-06)
Oxidative stress and inflammatory conditions are among the pathological features associated with the central nervous system in Alzheimer׳s disease. Traditionally, medicinal plants have been used to alleviate inflammation, pains and also other symptoms possibly associated with Alzheimer׳s disease. Therefore, the
Oier Aizpurua-Olaizola et al.
Journal of food science, 80(1), E101-E107 (2014-12-05)
In this study, supercritical fluid extraction has been successfully applied to a sequential fractionation of fatty acids and polyphenols from wine wastes (2 different vitis vinifera grapes). To this aim, in a 1st step just fatty acids were extracted and
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