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Marcin Lemanowicz et al.
Water research, 46(13), 4091-4098 (2012-06-05)
The impact of suspension heating method on the flocculation process using thermosensitive polymer is reported in this paper. In experiments a model suspension of chalk in RO water (purified by Reverse Osmosis) was destabilized using a copolymer of N-isopropylacrylamide (NIPAM)
Yuan-Jen Chang et al.
PloS one, 7(10), e44905-e44905 (2012-10-19)
In this study, a two-level full factorial design was used to identify the effects of the interactions between compositions in an N-isopropylacrylamide (NIPAM) gel dosimeter involving the following variables: (A) gelatin, (B) NIPAM, (C) the crosslinker N, N'-methylene-bis-acrylamide (Bis), and
Weitai Wu et al.
Journal of diabetes science and technology, 6(4), 892-901 (2012-08-28)
The concept of closed-loop control of glucose, in which continuous glucose sensing is coupled to a fully automated insulin delivery device, without human input, has been an attractive idea for diabetes management. This study presents a new class of hybrid
Polymerizing nonfluorescent monomers without incorporating any fluorescent agent produces strong fluorescent polymers.
Jun-Jie Yan et al.
Advanced materials (Deerfield Beach, Fla.), 24(41), 5617-5624 (2012-08-29)
Daisong Hou et al.
Journal of chromatography. A, 1349, 30-36 (2014-05-27)
Aqueous two-phase systems are efficient purification methods for bioproducts. However, recovery difficulty of the copolymers forming aqueous two-phase systems becomes obstacle in scale-up application. In the study, novel recyclable aqueous two-phase systems have been developed by using two thermo-responsive copolymers
Tobias K H Müller et al.
Journal of chromatography. A, 1285, 97-109 (2013-03-14)
An integrated approach to temperature-controlled chromatography, involving copolymer modified agarose adsorbents and a novel travelling cooling zone reactor (TCZR) arrangement, is described. Sepharose CL6B was transformed into a thermoresponsive cation exchange adsorbent (thermoCEX) in four synthetic steps: (i) epichlorohydrin activation;
Shannon E Bakarich et al.
Macromolecular rapid communications, 36(12), 1211-1217 (2015-04-14)
A smart valve is created by 4D printing of hydrogels that are both mechanically robust and thermally actuating. The printed hydrogels are made up of an interpenetrating network of alginate and poly(N-isopropylacrylamide). 4D structures are created by printing the "dynamic"
Zifu Li et al.
Langmuir : the ACS journal of surfaces and colloids, 31(23), 6282-6288 (2015-04-04)
Two distinct uniform hybrid particles, with similar hydrodynamic diameters and comparable zeta potentials, were prepared by copolymerizing N-isopropylacrylamide (NIPAM) and styrene. These particles differed in their styrene to NIPAM (S/N) mass ratios of 1 and 8 and are referred to
Yamin Li et al.
Biomacromolecules, 13(11), 3877-3886 (2012-09-28)
Polymeric drug nanocarriers integrated with diagnostic and sensing functions are capable of in situ monitoring the biodistribution of chemotherapeutic drugs and imaging/contrasting agents, which enables the establishment of image-guided personalized cancer therapeutic protocols. Responsive multifunctional theranostic nanocarriers possessing external stimuli-tunable
Muhammad Zafar et al.
Materials science & engineering. C, Materials for biological applications, 40, 135-141 (2014-05-27)
The present investigation involves the preparation and characterisation of silver containing nanogels and their incorporation onto the surface of woven fabrics so that they can be potentially used in biomedical applications such as wound dressings. These silver nanoparticles were mixed
Gerard H Bode et al.
PloS one, 10(5), e0126136-e0126136 (2015-05-23)
The aim of the current study was to develop a method to detect peptide-linked nanoparticles in blood plasma. A convenient enzyme linked immunosorbent assay (ELISA) was developed for the detection of peptides functionalized with biotin and fluorescein groups. As a
Bojan Mitrovic et al.
Langmuir : the ACS journal of surfaces and colloids, 29(2), 696-700 (2012-12-19)
A cationic polymer nanobrush was synthesized, attached to a MALDI target, and used for the fractionation of peptides and proteins based on their pI, prior to analysis by MALDI-MS. The cationic polymer nanobrush was synthesized on a gold substrate by
Tapas Palai et al.
Enzyme and microbial technology, 70, 42-49 (2015-02-11)
In an earlier study by us [47], thermo-responsive bioconjugate (poly-N-isopropylacrylamide-β-galactosidase) was synthesized and characterized. This study utilizes the prowess of such smart bioconjugate for the enzymatic synthesis of galacto-oligosaccharides (GOS) from lactose at various initial lactose concentrations (ILC), enzyme concentrations
Shixuan Chen et al.
Scientific reports, 5, 18104-18104 (2015-12-09)
The purpose of this study was to permit bone marrow mesenchymal stem cells (BMSCs) to reach their full potential in the treatment of chronic wounds. A biocompatible multifunctional crosslinker based temperature sensitive hydrogel was developed to deliver BMSCs, which improve
Jason Ng et al.
Environmental science & technology, 53(11), 6436-6443 (2019-05-07)
In the current study, a novel stimuli-responsive hybrid polymer with aluminum hydroxide colloids incorporated into a cationic copolymer of N-isopropylacrylamide and N-[3-(dimethylamino)propyl]methacrylamide was synthesized to enhance the settling and filtration performance of fine clay suspensions. The conformation of the synthesized
Yuwei Hao et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 19(16), 2107-2112 (2018-03-16)
To overcome the low efficiency of single-responsive smart surfaces, we have constructed a dual-responsive smart surface - poly(spiropyran-co-N-isopropylacrylamide) (poly(SP-co-NiPAAm))-grafted silicon nanowire arrays - by combining photo-responsive SP and thermo-responsive NiPAAm units for enhancing the efficiencies of cancer-cell capture and release.
Ming-Yue Jiang et al.
ACS applied materials & interfaces, 6(21), 19405-19415 (2014-10-18)
A novel type of smart microspheres with K(+)-induced shrinking and aggregating properties is designed and developed on the basis of a K(+)-recognition host-guest system. The microspheres are composed of cross-linked poly(N-isopropylacrylamide-co-acryloylamidobenzo-15-crown-5) (P(NIPAM-co-AAB15C5)) networks. Due to the formation of stable 2:1
Hua Chen et al.
Journal of colloid and interface science, 448, 65-72 (2015-02-28)
A series of novel thermo-responsive composite sorbents, were prepared by free-radical co-polymerization of N-isopropylacrylamide (NIPAm) and the silylanized Mg/Al layered double hydroxides (SiLDHs), named as PNIPAm-co-SiLDHs. For keeping the high affinity of Mg/Al layered double hydroxides towards anions, the layered
Ryan Odgers et al.
Clinical orthopaedics and related research, 471(10), 3141-3146 (2013-02-23)
Local delivery is required to achieve the high antimicrobial concentrations needed to treat biofilm-forming infections. The delivery site is commonly either in the intramedullary canal or at the periosteal surface. It is unknown whether locally delivered antimicrobials are transported transcortically
Trevor Gilbert et al.
ACS applied materials & interfaces, 9(48), 42179-42191 (2017-11-14)
Herein, we comprehensively investigate the internal morphology of fully injectable interpenetrating networks (IPNs) prepared via coextrusion of functionalized precursor polymer solutions based on thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) and nonthermoresponsive poly(vinyl pyrrolidone) (PVP) by reactive mixing using kinetically orthogonal hydrazone and thiosuccinimide
Sebastian Seiffert et al.
Journal of colloid and interface science, 452, 38-42 (2015-04-29)
Microfluidic droplet templating produces monodisperse particles of well controllable sizes, but this is limited by the necessity to operate microfluidic devices at low flow rates in the dripping regime. Here, the per-channel rate of droplet production could be substantially increased
Fernando Benito-Lopez et al.
Lab on a chip, 14(18), 3530-3538 (2014-07-16)
This paper reports for the first time the use of a cross-linked poly(N-isopropylacrylamide) ionogel encapsulating the ionic liquid 1-ethyl-3-methylimidazolium ethyl sulphate as a thermoresponsive and modular microfluidic valve. The ionogel presents superior actuation behaviour to its equivalent hydrogel. Ionogel swelling
Soleyman Hosseinzadeh et al.
Ecotoxicology and environmental safety, 161, 34-44 (2018-06-02)
In this study, magnetic multi-walled carbon nanotube (MMWCNT) composites were prepared via surface reversible addition fragmentation chain transfer (RAFT) co-polymerization of acrylic acid (AA) and N-isopropyl acrylamide (NIPAM) in the presence of Fe3O4 nanoparticles. First, a novel RAFT agent (RA)
David S Jones et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(3), 563-571 (2012-09-04)
Thermoresponsive polymeric platforms are used to optimise drug delivery in pharmaceutical systems and bioactive medical devices. However, the practical application of these systems is compromised by their poor mechanical properties. This study describes the design of thermoresponsive semi-interpenetrating polymer networks
R Yoshida
Nihon rinsho. Japanese journal of clinical medicine, 56(3), 670-674 (1998-04-29)
Poly (N-isopropylacrylamide) (PNIPAAm) gels were found to undergo discontinuous swelling-deswelling changes in response to a limited alteration in external temperatures. By utilizing such as thermosensitive characteristic of the PNIPAAm gel, controlled drug release was studied extensively. Drug release profiles were
Jianxu Zhang et al.
Colloids and surfaces. B, Biointerfaces, 129, 54-62 (2015-04-02)
In this paper, N-isopropylacrylamide-modified polyethylenimine (PEN) was constructed through Michael addition and employed as a carrier to achieve the p53 gene delivery, using HeLa (p53wt) and PC-3 cells (p53null) as models. After PEN-mediated p53 transfection, expression level of p53 in
Ying Gong et al.
Journal of biomaterials applications, 30(2), 201-211 (2015-03-15)
Magnetic, luminescent, and thermoresponsive multifunctional nanospheres composed of modified Fe3O4 nanoparticles as the core and rare earth complex Tb(AA)3Phen as the shell are synthesized by emulsifier-free emulsion polymerization. The core-shell spherical structure has a size between 140 and 220 nm and
Hien The Ho et al.
Macromolecular rapid communications, 33(20), 1753-1758 (2012-07-13)
A new azlactone-derived trithiocarbonate is prepared and used as a chain-transfer agent to mediate the reversible addition-fragmentation chain transfer (RAFT) polymerization of styrene, ethyl acrylate, and N-isopropyl acrylamide. Well-defined polymers with controlled molecular weights (M(n) = 1000-7000 g mol(-1)
Barney M Bishop et al.
PloS one, 10(2), e0117394-e0117394 (2015-02-12)
Cationic antimicrobial peptides and their therapeutic potential have garnered growing interest because of the proliferation of bacterial resistance. However, the discovery of new antimicrobial peptides from animals has proven challenging due to the limitations associated with conventional biochemical purification and
Hye In Seo et al.
Nanomedicine : nanotechnology, biology, and medicine, 11(7), 1861-1869 (2015-06-21)
We report thermo-responsive retinoic acid (RA)-loaded poly(N-isopropylacrylamide)-co-acrylamide (PNIPAM-co-Am) nanoparticles for directing human induced pluripotent stem cell (hiPSC) fate. Fourier transform infrared spectroscopy and (1)H nuclear magnetic resonance analysis confirmed that RA was efficiently incorporated into PNIAPM-co-Am nanoparticles (PCANs). The size
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