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Effect of blood-retinal barrier development on formation of selenite nuclear cataract in rat.

Hongjie Chen et al.

Toxicology letters, 216(2-3), 181-188 (2012-12-01)

Selenite cataract, as an experimental animal model of nuclear cataract to mimic human senile cataract, is produced only when overdose selenite is injected to neonatal rats before eyelid opening. To clarify the cause of age differences on selenite cataract formation

Optimization of selenylation conditions for Chinese angelica polysaccharide based on immune-enhancing activity.

Tao Qin et al.

Carbohydrate polymers, 92(1), 645-650 (2012-12-12)

Chinese angelica polysaccharide (CAP) was extracted by water decoction and ethanol precipitation, purified through eliminating protein by Sevage method and column chromatography of Sephadex G-200, then selenizingly modified by nitric acid-sodium selenite method according to L(9)(3(4)) orthogonal design of three-factors

Selenite stimulates mitochondrial biogenesis signaling and enhances mitochondrial functional performance in murine hippocampal neuronal cells.

Natalia Mendelev et al.

PloS one, 7(10), e47910-e47910 (2012-10-31)

Supplementation of selenium has been shown to protect cells against free radical mediated cell damage. The objectives of this study are to examine whether supplementation of selenium stimulates mitochondrial biogenesis signaling pathways and whether selenium enhances mitochondrial functional performance. Murine

Colostrum and milk selenium, antioxidative capacity and immune status of dairy cows fed sodium selenite or selenium yeast.

Saeed Salman et al.

Archives of animal nutrition, 67(1), 48-61 (2013-01-10)

Dietary selenium (Se) can be supplemented from organic or inorganic sources and this may affect Se metabolism and functional outcome such as antioxidative status and immune functions in dairy cows. A feeding trial was performed with 16 Holstein-Friesian dairy cows

Influence of trace elements on stabilization of aqueous solutions of ascorbic acid.

Barbara Dolińska et al.

Biological trace element research, 150(1-3), 509-512 (2012-10-27)

Together with vitamin C, zinc, selenium, manganese, and magnesium play a vital role in the preservation of organs scheduled for transplantation. In the present study, it is shown that addition of 1 mg/l of these elements influences the stability of 0.3 mM

Biological and chemical investigation of Allium cepa L. response to selenium inorganic compounds.

Michalska-Kacymirow M, et al.

Analytical and Bioanalytical Chemistry, 406(15), 3717-3722 (2014)

Sodium selenite improves folliculogenesis in radiation-induced ovarian failure: a mechanistic approach.

Riham S Said et al.

PloS one, 7(12), e50928-e50928 (2012-12-14)

Radiotherapy is a major factor contributing to female infertility by inducing premature ovarian failure (POF). Therefore, the need for an effective radioprotective agent is evident. The present study investigated the mechanism of potential radioprotective effect of sodium selenite on radiation-induced

Selenium bioaccessibility and bioavailability in Se-enriched food supplements.

Celine Thiry et al.

Biological trace element research, 152(1), 152-160 (2013-02-12)

Most European people have selenium (Se) intake inferior to recommended values that are considered necessary to ensure the beneficial action of antioxidant selenoproteins. People could therefore tend to have recourse to Se-enriched food supplements (FS) aiming to increase their Se

High-dose sodium selenite toxicity cannot be prevented by the co-administration of pharmacological levels of epigallocatechin-3-gallate which in turn aggravates the toxicity.

Kang Sun et al.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 52, 36-41 (2012-11-10)

Selenium, an essential trace element, can also be toxic at higher levels of exposure. Several lines of evidence show epigallocatechin-3-gallate (EGCG), a predominant component of green tea catechins with numerous health benefits, can ameliorate the toxicity of many agents. A

Selenium species and their distribution in freshwater fish from Argentina.

Urška Kristan et al.

Biological trace element research, 151(2), 240-246 (2012-12-18)

The distribution and speciation of selenium (Se) in freshwater fish (muscle and liver tissue) from lakes in Argentina was investigated. Three introduced species, brown trout (Salmo trutta), rainbow trout (Oncorhynchus mykiss) and brook trout (Salvelinus fontinalis), and one native species

Sodium selenite alters microtubule assembly and induces apoptosis in vitro and in vivo.

Kejian Shi et al.

Journal of hematology & oncology, 6, 7-7 (2013-01-19)

Previous studies demonstrated that selenite induced cancer-cell apoptosis through multiple mechanisms; however, effects of selenite on microtubules in leukemic cells have not been demonstrated. The toxic effect of selenite on leukemic HL60 cells was performed with cell counting kit 8.

PTEN-regulated AKT/FoxO3a/Bim signaling contributes to reactive oxygen species-mediated apoptosis in selenite-treated colorectal cancer cells.

H Luo et al.

Cell death & disease, 4, e481-e481 (2013-02-09)

Mounting evidence shows that selenium possesses chemotherapeutic potential against tumor cells, including leukemia, prostate cancer and colorectal cancer (CRC) cells. However, the detailed mechanism by which sodium selenite specifically kills tumor cells remains unclear. Herein, we demonstrated that supranutritional doses

Vibrational spectra of alkali hydrogen selenites, selenous acid, and their deuterated analogs.

Cody CA, et al.

Journal of Solid State Chemistry, 26(3), 281-291 (1978)

Evaluation of selenite effects on selenoproteins and cytokinome in human hepatoma cell lines.

Fabiola Rusolo et al.

Molecules (Basel, Switzerland), 18(3), 2549-2562 (2013-02-28)

The need to explore new alternative therapeutic strategies and chemoprevention methods for hepatocellular carcinoma is growing significantly. Selenium is a trace element that plays a critical role in physiological processes, and is used in cancer chemoprevention. The aim of this

The diversity, evolution and ecology of Salmonella in venomous snakes.

Caisey V Pulford et al.

PLoS neglected tropical diseases, 13(6), e0007169-e0007169 (2019-06-05)

Reptile-associated Salmonella bacteria are a major, but often neglected cause of both gastrointestinal and bloodstream infection in humans globally. The diversity of Salmonella enterica has not yet been determined in venomous snakes, however other ectothermic animals have been reported to

A new enrichment medium for salmonellae.

Banic S.

J. Hyg. (Lond), 62(1), 25-28 (1964)

Bioavailability, toxicity and biotransformation of selenium in midge (Chironomus dilutus) larvae exposed via water or diet to elemental selenium particles, selenite, or selenized algae.

Mercedes Gallego-Gallegos et al.

Environmental science & technology, 47(1), 584-592 (2012-12-14)

Elemental selenium (Se) is generally considered to be biologically inert due to its insolubility in water. It is a common form of Se in sediment near uranium mining and milling operations in northern Saskatchewan, Canada. Nanosized particles of many materials

Porcine serum can be biofortified with selenium to inhibit proliferation of three types of human cancer cells.

Lv-Hui Sun et al.

The Journal of nutrition, 143(7), 1115-1122 (2013-05-17)

Our objectives were to determine if porcine serum could be enriched with selenium (Se) by feeding pigs with high concentrations of dietary Se and if the Se-biofortified serum inhibited proliferation of 3 types of human cancer cells. In Expt. 1

Application of reversed-phase high-performance liquid chromatography with fluorimetric detection for simultaneous assessment of global DNA and total RNA methylation in Lepidium sativum: effect of plant exposure to Cd(II) and Se(IV).

Eunice Yanez Barrientos et al.

Analytical and bioanalytical chemistry, 405(7), 2397-2404 (2013-01-17)

In the present work, application of the previously established reversed-phase liquid chromatography procedure based on fluorescent labeling of cytosine and methylcytosine moieties with 2-bromoacetophenone (HPLC-FLD) is presented for simultaneous evaluation of global DNA and total RNA methylation at cytosine carbon

Evaluation of pharmacological activities and assessment of intraocular penetration of an ayurvedic polyherbal eye drop (Itone™) in experimental models.

Thirumurthy Velpandian et al.

BMC complementary and alternative medicine, 13, 1-1 (2013-01-03)

The polyherbal eye drop (Itone™) is a mixture of aqueous distillates of nineteen traditionally used ingredients that sum up to impart potency to the formulation and make it a useful adjunct in various ocular pathologies. However, as there have been

Effects of dietary selenium supplementation on tissue selenium distribution and glutathione peroxidase activity in Chinese Ring necked Pheasants.

D T Juniper et al.

Animal : an international journal of animal bioscience, 7(4), 562-570 (2012-12-04)

The objective of this study was to determine the concentration of total selenium (Se) and the proportions of total Se comprised as selenomethionine (SeMet) and selenocysteine (SeCys) in the postmortem tissues of female pheasants (Phasianus Colchicus Torquator) offered diets that

Selenium (sodium selenite) causes cytotoxicity and apoptotic mediated cell death in PLHC-1 fish cell line through DNA and mitochondrial membrane potential damage.

Vellaisamy Selvaraj et al.

Ecotoxicology and environmental safety, 87, 80-88 (2012-11-20)

Elevated concentration of selenium poses a toxic threat to organisms inhabiting aquatic ecosystems influenced by excessive inputs from anthropogenic sources. Selenium is also an essential micronutrient in living things, particularly in fish, and provides antioxidant properties to tissues. Whole fish

Co-application of selenite and phosphate reduces arsenite uptake in hydroponically grown rice seedlings: toxicity and defence mechanism.

Navin Kumar et al.

Ecotoxicology and environmental safety, 91, 171-179 (2013-03-05)

The study empirically evaluates the abatement of As(III) uptake in rice seedlings (7d), in presence of Se and phosphate (P) under hydroponic condition. Positive correlation between As(III) translocation to the shoots of As(III) and P treated seedlings, shows P dependent

Effects of selenoprotein P on the contraction and relaxation of the airway smooth muscle.

Sachie K Ogawa et al.

General physiology and biophysics, 32(1), 47-54 (2013-03-28)

Selenoprotein P (SeP) not only represents the major selenoprotein in plasma, but also provides more than 50% of the total plasma selenium. However, there is no report concerning the direct action of selenium or selenium-containing compounds on the contraction and

Selenite adsorption using leached residues generated by reduction roasting-ammonia leaching of manganese nodules.

N S Randhawa et al.

Journal of hazardous materials, 241-242, 486-492 (2012-10-25)

This study was carried out to investigate the adsorption characteristics of leached manganese nodule residue (MNR), generated from the reduction roasting-ammonia leaching process, towards aqueous selenite. Physicochemical characterization revealed that the leached residue was a complex mixture of oxides of

Direct differentiation of hepatic stem-like WB cells into insulin-producing cells using small molecules.

Jianping Liu et al.

Scientific reports, 3, 1185-1185 (2013-02-05)

Recent evidence suggests that experimental induction of hepatocytes into pancreatic cells provides new cell transplantation therapy prospects for type 1 diabetes mellitus. Stepwise differentiation from rat liver epithelial stem-like WB-F344 cells (WB cells) into functional insulin-secreting cells will identify key

Characterization of cytosolic glutathione peroxidase and phospholipid-hydroperoxide glutathione peroxidase genes in rainbow trout (Oncorhynchus mykiss) and their modulation by in vitro selenium exposure.

D Pacitti et al.

Aquatic toxicology (Amsterdam, Netherlands), 130-131, 97-111 (2013-02-07)

Selenium (Se) is an oligonutrient with both essential biological functions and recognized harmful effects. As the selenocysteine (SeCys) amino acid, selenium is integrated in several Se-containing proteins (selenoproteins), many of which are fundamental for cell homeostasis. Nevertheless, selenium may exert

Effect of sulfide, selenite and mercuric mercury on the growth and methylation capacity of the sulfate reducing bacterium Desulfovibrio desulfuricans.

Hoang-Yen T Truong et al.

The Science of the total environment, 449, 373-384 (2013-03-05)

Cultures of the sulfate reducing bacteria Desulfovibrio desulfuricans were grown under anoxic conditions to study the effect of added sulfide, selenite and mercuric ions. A chemical trap consisting in a CuSO4 solution was used to control the poisoning effect induced

Oxidation inhibits iron-induced blood coagulation.

Etheresia Pretorius et al.

Current drug targets, 14(1), 13-19 (2012-11-23)

Blood coagulation under physiological conditions is activated by thrombin, which converts soluble plasma fibrinogen (FBG) into an insoluble clot. The structure of the enzymatically-generated clot is very characteristic being composed of thick fibrin fibers susceptible to the fibrinolytic degradation. However

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