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Caitlyn M Gatley et al.
Molecules (Basel, Switzerland), 20(6), 9616-9639 (2015-05-29)
While H2O2 is a powerful oxidant, decomposing into environmentally benign H2O and O2, a catalyst is often required for reactions with H2O2 to proceed at synthetically useful rates. Organotellurium and organoselenium compounds catalyze the oxidation of halide salts to hypohalous
Lei Zhang et al.
Nanoscale, 7(29), 12614-12624 (2015-07-07)
Nanomaterials for effective drug delivery require zero pre-release and on-demand release of therapeutic drugs. In this work we demonstrate a novel drug delivery system composed of a mesoporous silica platform conjugated to CuS nanoparticles with two complementary DNA sequences. CuS
Ángela A Beltrán-Osuna et al.
Langmuir : the ACS journal of surfaces and colloids, 28(25), 9700-9706 (2012-05-23)
In this work, a new antifouling silica hydrogel was developed for potential biomedical applications. A zwitterionic polymer, poly(carboxybetaine methacrylate) (pCBMA), was produced via atom-transfer radical polymerization and was appended to the hydrogel network in a two-step acid-base-catalyzed sol-gel process. The
Wei Li et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 88(3), 706-717 (2014-10-14)
Chemical modification of nanoclay will ensure further progress on these materials. In this work, we show that montmorillonite (MTM) nanosheets can be modified with β-cyclodextrin (CD) via a nucleophilic substitution reaction between mono-6-(p-toluenesulfonyl)-6-deoxy-β-CD and an amino group of 3-aminopropyltriethoxysilane (APTES)-functionalized
Ali Mehdinia et al.
Journal of chromatography. A, 1364, 12-19 (2014-09-07)
In order to resolve the low adsorption capacity of the surface molecularly imprinting methods, an approach was developed for the preparation of magnetic imprinted polymers by pre-grafting the amino functional material, 3-aminopropyltriethoxysilane (APTES), on the surface of the silica coated
N L O'Regan et al.
Parasite immunology, 36(12), 713-720 (2014-08-16)
Helminths induce strong regulatory and T helper 2-type responses, whereby antibody-derived host protection and regulation are essential components. Lymphatic filariasis is an immune-mediated spectral disease that manifests as two main clinical outcomes: chronic pathology or asymptomatic infection. These outcomes depend
Jian Li et al.
Journal of chromatographic science, 53(4), 641-645 (2014-07-06)
A new capillary electrophoresis (CE) method was developed by using graphene oxide (GO) as a stationary phase for the separation of brucine and strychnine. The separation performance, reproducibility and stability of GO-coated capillary were investigated for the analysis of brucine
Licheng Wang et al.
Journal of separation science, 38(14), 2439-2446 (2015-05-02)
A novel graphene oxide decorated with silver nanoparticles coating on a stainless-steel fiber for solid-phase microextraction was prepared. Scanning electron microscopy and X-ray photoelectron spectroscopy were used to characterize the coating surface and showed that silver nanoparticles were dispersed on
Sanna Byström et al.
Journal of proteome research, 13(11), 4607-4619 (2014-09-19)
The brain is a vital organ and because it is well shielded from the outside environment, possibilities for noninvasive analysis are often limited. Instead, fluids taken from the spinal cord or circulatory system are preferred sources for the discovery of
Kellie I McConnell et al.
Journal of controlled release : official journal of the Controlled Release Society, 194, 113-121 (2014-09-03)
There is an unmet clinical need to increase lung transplant successes, patient satisfaction and to improve mortality rates. We offer the development of a nanovector-based solution that will reduce the incidence of lung ischemic reperfusion injury (IRI) leading to graft
Jacquelyn A Brown et al.
Biomicrofluidics, 9(5), 054124-054124 (2015-11-18)
The blood-brain barrier (BBB) is a critical structure that serves as the gatekeeper between the central nervous system and the rest of the body. It is the responsibility of the BBB to facilitate the entry of required nutrients into the
Zhenghuan Zhao et al.
ACS nano, 9(3), 2749-2759 (2015-02-18)
Delivery of arsenic trioxide (ATO), a clinical anticancer drug, has drawn much attention to improve its pharmacokinetics and bioavailability for efficient cancer therapy. Real-time and in situ monitoring of ATO behaviors in vivo is highly desirable for efficient tumor treatment.
Hua Fan et al.
Biomedical chromatography : BMC, 29(12), 1834-1841 (2015-06-11)
Salbutamol (SAL) is the most widely used β2 -agonist drug for asthma and chronic obstructive pulmonary patients, but it is also often abused as feed additive. In recent years, the abuse of SAL has led to a large number of
Xuebin Ke et al.
Nanoscale research letters, 9(1), 2492-2492 (2015-06-20)
Metal-enhanced fluorescence (MEF) as a newly recognized technology has been attracting considerable attention and is widely used in fluorescence-based technology. In this paper, we reported a novel distance-dependent MEF and metal-enhanced singlet oxygen generation phenomenon based on silica-coated gold nanorods
Vishakha Singh et al.
Life sciences, 122, 51-58 (2014-12-23)
The aim of the present study was to characterize TRPV4 channels in pregnant and nonpregnant mouse uterus and examine their functional role in spontaneous and agonist-induced contractions. We used RT-PCR, Western blot and immunohistochemistry experiments to demonstrate the presence of
Manuela Herklotz et al.
Biomaterials, 60, 121-129 (2015-05-20)
To explore the space-filling growth of adherent mesenchymal stem cells (MSC) into tissue-like structures in vitro, human bone marrow derived MSC were exposed to fibronectin-coated, millimeter-sized, triangular channels casted in poly(dimethyl siloxane) carriers. The results revealed that the three dimensional (3D)
Yang Liu et al.
The Analyst, 139(20), 5086-5092 (2014-08-12)
A carbon nanotube (CNT) based nanoarchitecture is developed for rapid, sensitive and specific detection of cancer cells by using real time electrical impedance sensing. The sensor is constructed with carbon nanotube (CNT) multilayers and EpCAM (epithelial cell adhesion molecule) antibodies
Xiaohui Feng et al.
Colloids and surfaces. B, Biointerfaces, 125, 197-205 (2014-12-17)
In this paper, a novel folic acid-conjugated silica-coated titanium dioxide (TiO2-SiO2) photosensitizer was synthesized and characterized using various analytical instruments. The photosensitizer was further assessed with regards to its photoreactivity, cellular and hemocompatibility, cell internalization, and phototoxicity. Conjugating folic acid
Ying Cheong et al.
Fertility and sterility, 102(3), 899-907 (2014-07-27)
To examine the effects of high-fat (HF) diet-induced maternal obesity on follicular population and gene expression in adult offspring ovaries. Experimental mouse study. Laboratory. Mice on HF diet. Female C57BL/6J mice were fed an HF or standard chow (C) diet
M Ghasemnejad et al.
Materials science & engineering. C, Materials for biological applications, 56, 223-232 (2015-08-08)
Mesoporous silica nanoparticles with a hexagonal structure (SBA-15) were synthesized and modified with (3-aminopropyl) triethoxysilane (APTES), and their performance as a carrier for drug delivery system was studied. Chemical structure and morphology of the synthesized and modified SBA-15 were characterized
Ye Zhang et al.
ACS applied materials & interfaces, 7(19), 10201-10212 (2015-05-06)
In this study, a biocompatible nanoplatform has been constructed on the basis of magnetic mesoporous silica nanoparticles (Fe3O4@mSiO2) via surface modification of triphenylphospine (TPP) and then conjugation with fluorescent carbon dots (CDs). The as-prepared Fe3O4@mSiO2-TPP/CDs nanoplatform shows a very low
M I Mohammed et al.
Biosensors & bioelectronics, 61, 478-484 (2014-06-18)
Cardiovascular diseases are the most prevalent medical conditions affecting the modern world, reducing the quality of life for those affected and causing an ever increasing burden on clinical resources. Cardiac biomarkers are crucial in the diagnosis and management of patient
Lei Zhou et al.
Nature communications, 6, 6938-6938 (2015-04-25)
The identification of potential diagnostic markers and target molecules among the plethora of tumour oncoproteins for cancer diagnosis requires facile technology that is capable of quantitatively analysing multiple biomarkers in tumour cells and tissues. Diagnostic and prognostic classifications of human
F M Rodríguez et al.
Reproduction in domestic animals = Zuchthygiene, 50(4), 659-668 (2015-06-03)
Cystic ovarian disease (COD) is one of the main causes of infertility in dairy cattle. It has been shown that intra-ovarian factors, such as members of the insulin-like growth factor (IGF) system, may contribute to follicular persistence. The bioavailability of
Sergi Hernàndez-Navarro et al.
Angewandte Chemie (International ed. in English), 53(40), 10696-10700 (2014-08-21)
Different phoretic driving mechanisms have been proposed for the transport of solid or liquid microscopic inclusions in integrated chemical processes. It is now shown that a substrate that was chemically modified with photosensitive self-assembled monolayers enables the direct control of
Ilaria Rea et al.
Biochimica et biophysica acta, 1840(12), 3393-3403 (2014-09-17)
Diatomite is a natural porous biomaterial of sedimentary origin, formed by fragments of diatom siliceous skeletons, called "frustules". Due to large availability in many areas of the world, chemical stability, and non-toxicity, these fossil structures have been widespread used in
Silvia Minardi et al.
ACS applied materials & interfaces, 7(30), 16364-16373 (2015-06-26)
In regenerative medicine, the temporospatially controlled delivery of growth factors (GFs) is crucial to trigger the desired healing mechanisms in the target tissues. The uncontrolled release of GFs has been demonstrated to cause severe side effects in the surrounding tissues.
Wenlei Xie et al.
Food chemistry, 194, 1283-1292 (2015-10-17)
A core-shell structured Fe3O4-MCM-41 nanocomposite was prepared by means of a surfactant-directed sol-gel process. Candida rugosa lipase was then bound to the magnetic core-shell material by using glutaraldehyde as a cross-linking reagent. The as-prepared Fe3O4-MCM-41 support and the immobilized lipase
Chenchen Qin et al.
Nanoscale, 7(47), 20197-20210 (2015-11-18)
To optimize synergistic cancer therapy, we rationally assemble an inorganic-organic nanocomplex using a folate-modified lipid bilayer spread on photosensitizer-entrapped mesoporous silica nanoparticle (MSN) coated gold nanorods (AuNRs). In this hybrid bioconjugate, the large specific surface area and pore size of
Pei-Ru Wei et al.
International journal of molecular sciences, 16(9), 20943-20968 (2015-09-05)
We designed a study for photodynamic therapy (PDT) using chitosan coated Mg-Al layered double hydroxide (LDH) nanoparticles as the delivery system. A Food and Drug Administration (FDA) approved near-infrared (NIR) fluorescent dye, indocyanine green (ICG) with photoactive properties was intercalated
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