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Fabrication and characterisation of ligand-functionalised ultrapure monodispersed metal nanoparticle nanoassemblies employing advanced gas deposition technique.
Welearegay TG, et al.
Nanotechnology, 29(6), 065603-065603 (2018)
Jiadi Sun et al.
Biosensors & bioelectronics, 70, 239-245 (2015-04-02)
A novel DNA sensor for the detection of the Escherichia coli O157:H7 (E. coli O157:H7) eaeA gene was constructed using surface enhanced fluorescence (SEF). The spacing distance dependence nature of Au@Ag nanorods surface enhanced fluorescence was investigated when the cy3-labled
Onur Tokel et al.
Scientific reports, 5, 9152-9152 (2015-03-25)
Timely detection of infectious agents is critical in early diagnosis and treatment of infectious diseases. Conventional pathogen detection methods, such as enzyme linked immunosorbent assay (ELISA), culturing or polymerase chain reaction (PCR) require long assay times, and complex and expensive
Manuel S Schroeter et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(14), 5459-5470 (2015-04-10)
Recent studies demonstrated that the anatomical network of the human brain shows a "rich-club" organization. This complex topological feature implies that highly connected regions, hubs of the large-scale brain network, are more densely interconnected with each other than expected by
Camille Daniel et al.
Analytical biochemistry, 473, 66-71 (2015-01-15)
Microarrays are particular biosensors with multiple grafted probes that are generally used for parallel and simultaneous detection of various targets. In this study, we used microarrays with aptamer probes in order to follow up the different biomolecular interactions of a
Nikhil Bhalla et al.
Biosensors & bioelectronics, 71, 121-128 (2015-04-22)
Protein kinases are cellular switches that mediate phosphorylation of proteins. Abnormal phosphorylation of proteins is associated with lethal diseases such as cancer. In the pharmaceutical industry, protein kinases have become an important class of drug targets. This study reports a
Jiangping Chen et al.
Sensors (Basel, Switzerland), 15(6), 12205-12217 (2015-05-29)
In this study, we developed a reflective localized surface plasmon resonance (LSPR) optical fiber sensor, based on silver nanoparticles (Ag NPs). To enhance the sensitivity of the LSPR optical sensor, two key parameters were optimized, the length of the sensing
Sławomir Oszwałdowski et al.
Journal of chromatography. A, 1412, 139-150 (2015-08-25)
Capillary electrophoresis coupled with contactless conductivity detector was applied to characterize BGE/segment/segment/BGE and BGE/segment/electrolyte/segment/BGE systems, where segment is the phase of mixed micelles migrating surrounded by BGE and composition of the first segment≠second segment. It was established that both systems
Hojae Lee et al.
Scientific reports, 6, 38517-38517 (2016-12-06)
Inspired by the biogenic magnetism found in certain organisms, such as magnetotactic bacteria, magnetic nanomaterials have been integrated into living cells for bioorthogonal, magnetic manipulation of the cells. However, magnetized cells have so far been reported to be only binary
Mihaela Puiu et al.
Sensors (Basel, Switzerland), 15(5), 10511-10525 (2015-05-08)
We report a Love wave surface acoustic wave (LW-SAW) immunosensor designed for the detection of high molecular weight targets in liquid samples, amenable also for low molecular targets in surface competition assays. We implemented a label-free interaction protocol similar to
Phillip J Brumm et al.
Frontiers in microbiology, 6, 430-430 (2015-06-02)
In this work we report the whole genome sequences of six new Geobacillus xylanolytic strains along with the genomic analysis of their capability to degrade carbohydrates. The six sequenced Geobacillus strains described here have a range of GC contents from
Kai Jin et al.
Analytica chimica acta, 1067, 48-55 (2019-05-03)
Immunoassay is a powerful technique to identify and quantify biological molecules, which base on the specificity and selectivity of antigen-antibody interaction. Impedance-based immunosensor has recently shown a great potential to provide rapid and label-free detections. However, the conventional impedance-based immunosensors
Maria Pawula et al.
Talanta, 146, 823-830 (2015-12-24)
A surface plasmon resonance (SPR) sensor developed for the rapid, sensitive and specific detection of cardiac troponin T (cTnT) in serum samples is reported in this work. An extensive optimisation of assay parameters was conducted to achieve optimal detection strategy.
Marsilea Adela Booth et al.
Langmuir : the ACS journal of surfaces and colloids, 31(29), 8033-8041 (2015-06-25)
Aminoferrocene is used as an electroactive indicator to investigate carbodiimide coupling reactions on a carboxylic acid-functionalized self-assembled monolayer. The commonly used attachment chemistry with 1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) is used for surface activation. A number of conditions are
Matthew R Lockett et al.
Langmuir : the ACS journal of surfaces and colloids, 24(1), 69-75 (2007-12-01)
A tetrafluorophenyl (TFP) ester-terminated self-assembled monolayer (SAM) for the fabrication of DNA arrays on gold surfaces is described. Activated ester SAMs are desirable for biomolecule array fabrication because they readily react with amine-containing molecules to form a stable amide linkage.
Shogo Sasaki et al.
Journal of bioscience and bioengineering, 119(2), 200-205 (2014-07-26)
We demonstrated the synthesis of molecularly imprinted polymers (MIPs) with binding affinity toward a target protein, ribonuclease A (RNase) by atom transfer radical polymerization (ATRP) of acrylic acid, acrylamide, and N,N'-methylenebisacrylamide in the presence of RNase. The binding activity of
Dennis B Pacardo et al.
Nanoscale, 7(28), 12096-12103 (2015-07-01)
A multifunctional gold nanorod (AuNR) complex is described with potential utility for theranostic anticancer treatment. The AuNR was functionalized with cyclodextrin for encapsulation of doxorubicin, with folic acid for targeting, and with a photo-responsive dextran-azo compound for intracellular controlled drug
Y Inoue et al.
Journal of the Royal Society, Interface, 5(25), 909-918 (2008-01-15)
A transfection array, which is specifically developed for use in high-throughput analyses of genome functions by the over-expression or suppression of genes on a chip, is expected to become an important method for post-genome research. High efficiency of gene expression
Xiaohui Song et al.
Small (Weinheim an der Bergstrasse, Germany), 11(34), 4351-4365 (2015-06-13)
The origin of selectivity in the hollowing of silica nanoparticles is investigated to further understand silica. It is realized that, during the synthesis, the silica precursors are essentially ion-paired polyelectrolytes, whose nucleation depends on the concentration of the counter ions
Yun Liu et al.
Scientific reports, 5, 12864-12864 (2015-08-11)
We demonstrate a fiber optic surface plasmon resonance (SPR) biosensor based on smart phone platforms. The light-weight optical components and sensing element are connected by optical fibers on a phone case. This SPR adaptor can be conveniently installed or removed
Seokyung Kang et al.
ACS nano, 9(10), 9678-9690 (2015-09-09)
Gold nanoparticles (AuNPs) have been extensively studied for photothermal cancer therapy because AuNPs can generate heat upon near-infrared irradiation. However, improving their tumor-targeting efficiency and optimizing the nanoparticle size for maximizing the photothermal effect remain challenging. We demonstrate that mesenchymal
Tesfalem Geremariam Welearegay et al.
Nanotechnology, 29(6), 065603-065603 (2017-12-06)
Here, we report for the first time the fabrication of ligand-functionalised ultrapure monodispersed metal nanoparticles (Au, Cu, and Pt) from their pure metal precursors using the advanced gas deposition technique. The experimental conditions during nanoparticle formation were adjusted in order
Yang Shen et al.
Colloids and surfaces. B, Biointerfaces, 126, 188-197 (2015-01-13)
The migration of vascular endothelial cells (ECs) is essential for reendothelialization after implantation of cardiovascular biomaterials. Reendothelialization is largely determined by surface properties of implants. In this study, surfaces modified with various chemical functional groups (CH3, NH2, COOH, OH) prepared
Didem Cetin et al.
Colloids and surfaces. B, Biointerfaces, 188, 110808-110808 (2020-01-29)
Detection of circulating tumor cells (CTCs) from the bloodstream holds great importance to diagnose cancer at early stages. However, CTCs being extremely rare in blood makes them difficult to reach. In this paper, we introduced different surface modification techniques for
Jie He et al.
Analytical chemistry, 87(22), 11407-11414 (2015-10-24)
For applications ranging from medical diagnostics and drug screening to chemical and biological warfare detection, inexpensive, rapid-readout, portable devices are required. Localized surface plasmon resonance (LSPR) technologies show substantial promise toward meeting these goals, but the generation of portable, multiplexed
Anu Singh et al.
Bioelectrochemistry (Amsterdam, Netherlands), 105, 7-15 (2015-04-29)
Direct electro-deposition of gold nano-aggregates (GNAs) was carried out to fabricate electrochemical DNA biosensor for the detection of Salmonella typhi in urine and blood samples. Size of depositing GNAs was controlled by regulating electro-deposition parameters at physiological pH. This facilitated
Seshadri Reddy Ankireddy et al.
International journal of nanomedicine, 10 Spec Iss, 121-128 (2015-09-09)
Microbeads are frequently used as solid supports for biomolecules such as proteins and nucleic acids in heterogeneous microfluidic assays. Chip-based, quantum dot (QD)-bead-biomolecule probes have been used for the detection of various types of DNA. In this study, we developed
Development of single cell biochip platform based on silicon for multiple patch clamping technology.
2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, 29(6), 138-141 (2009)
Xi Qian et al.
Biomaterials, 75, 305-312 (2015-10-30)
Nanoscale curvature plays a critical role in nanostructure-biomolecule interactions, yet the understanding of such effects in concave nanostructures is still very limited. Because concave nanostructures usually possess convex surface curvatures as well, it is challenging to selectively study the proteins
Didem Rodoplu et al.
Current pharmaceutical design, 21(37), 5389-5400 (2015-09-18)
Magnetic nanoparticles are considered as the ideal substrate to selectively isolate target molecules or organisms from sample solutions in a wide variety of applications including bioassays, bioimaging and environmental chemistry. The broad array of these applications in fields requires the
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