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38796

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Luce Farine et al.
Scientific reports, 5, 16787-16787 (2015-11-19)
Phosphatidylethanolamine (PE) and phosphatidylcholine (PC) are among the most abundant phospholipids in biological membranes. In many eukaryotes, the CDP-ethanolamine and CDP-choline branches of the Kennedy pathway represent major and often essential routes for the production of PE and PC, with
D García-Párraga et al.
Diseases of aquatic organisms, 111(3), 191-205 (2014-10-17)
Decompression sickness (DCS), as clinically diagnosed by reversal of symptoms with recompression, has never been reported in aquatic breath-hold diving vertebrates despite the occurrence of tissue gas tensions sufficient for bubble formation and injury in terrestrial animals. Similarly to diving
David A Köpfer et al.
Science (New York, N.Y.), 346(6207), 352-355 (2014-10-18)
Potassium channels selectively conduct K(+) ions across cellular membranes with extraordinary efficiency. Their selectivity filter exhibits four binding sites with approximately equal electron density in crystal structures with high K(+) concentrations, previously thought to reflect a superposition of alternating ion-
A A Ivanov et al.
Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine, 47(5), 40-44 (2014-02-04)
Eighty outbred CD-I male and female mice (initial body mass of 31-34 g) and 40 male Wistar rats (initial body mass of 280-360 g) were randomly distributed into the experimental and control groups by sex and body mass. According to
Wei He et al.
Journal of environmental sciences (China), 25(3), 430-440 (2013-08-08)
Algae-caused black bloom (also known as black water agglomerate) has recently become a critical problem in some Chinese lakes. It has been suggested that the occurrence of algae-caused black bloom was caused by the cooperation of nutrient-rich sediment with dead
Faiza Tebbji et al.
PLoS genetics, 10(11), e1004770-e1004770 (2014-11-07)
Mediator is a multi-subunit protein complex that regulates gene expression in eukaryotes by integrating physiological and developmental signals and transmitting them to the general RNA polymerase II machinery. We examined, in the fungal pathogen Candida albicans, a set of conditional
Beatrice N Vetter et al.
BMC infectious diseases, 15, 468-468 (2015-10-30)
The detection of HIV-1 p24 antigen in diagnostic tests relies on antibodies binding to conserved areas of the protein to cover the full range of HIV-1 subtypes. Using a panel of 43 different virus-like particles (VLPs) expressing Gag from clinical
Quang Duc Truong et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 20(49), 16210-16215 (2014-10-10)
Atomic-resolution imaging of the crystal defects of cathode materials is crucial to understand their formation and the correlation between the structure, electrical properties, and electrode performance in rechargeable batteries. The polytype, a stable form of varied crystal structure with uniform
Y Ohira et al.
Journal of applied physiology: respiratory, environmental and exercise physiology, 42(5), 739-743 (1977-05-01)
Eleven, healthy male students were subjected to an exhaustive bicyle ergometer exercise. Many parameters of hemoconcentration were examined in blood and urine samples which were collected before and after exercise. In an exercise lasting approximately 10 min, it was found
Takashi Toyao et al.
ChemSusChem, 8(22), 3905-3912 (2015-09-24)
Various N-doped nanoporous carbons containing metal species were prepared by direct thermal conversion of zeolitic imidazolate frameworks (ZIFs; ZIF-7, -8, -9, and -67) at different temperatures (600, 800, and 1000 °C). These materials were utilized as bifunctional acid-base catalysts to promote
Jose C Paz et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(48), 17116-17121 (2014-11-19)
In the fasted state, increases in catecholamine signaling promote adipocyte function via the protein kinase A-mediated phosphorylation of cyclic AMP response element binding protein (CREB). CREB activity is further up-regulated in obesity, despite reductions in catecholamine signaling, where it contributes
Manar Al-Ghabeish et al.
International journal of pharmaceutics, 495(2), 783-791 (2015-09-08)
The availability of in vitro performance tests such as in vitro drug release testing (IVRT) and in vitro permeation testing (IVPT) are critical to comprehensively assure consistent delivery of the active component(s) from semisolid ophthalmic drug products. The objective was
Thandavarayan Maiyalagan et al.
Analytical chemistry, 86(15), 7849-7857 (2014-07-16)
Supported tungsten carbide is an efficient and vital nanomaterial for the development of high-performance, sensitive, and selective electrochemical sensors. In this work, tungsten carbide with tube-like nanostructures (WC NTs) supported platinum nanoparticles (PtNPs) are synthesized and explored as an efficient
Melanie Zischka et al.
BMC genomics, 16, 175-175 (2015-04-19)
Enterococcus faecalis is a multifaceted microorganism known to act as a beneficial intestinal commensal bacterium. It is also a dreaded nosocomial pathogen causing life-threatening infections in hospitalised patients. Isolates of a distinct MLST type ST40 represent the most frequent strain
Blessing Okai et al.
Infection and immunity, 83(4), 1523-1535 (2015-02-04)
Avoidance of innate immune defense is an important mechanism contributing to the pathogenicity of microorganisms. The fungal pathogen Candida albicans undergoes morphogenetic switching from the yeast to the filamentous hyphal form following phagocytosis by macrophages, facilitating its escape from the
Maarten Danial et al.
Organic & biomolecular chemistry, 13(8), 2464-2473 (2015-01-09)
The effect of amino acid composition on the formation of transmembrane channels in lipid bilayers upon self-assembly of alt-(L,D)-α-cyclic octapeptides has been investigated. Cyclic peptides comprising D-leucine, alternating with different combinations of L-azidolysine, L-lysine(Alloc), L-lysine and L-tryptophan were synthesized and
Wan-Jung Lu et al.
Thrombosis research, 134(6), 1301-1310 (2014-10-09)
CME-1, a novel water-soluble polysaccharide, was purified from the mycelia of Cordyceps sinensis, and its chemical structure was characterized to contain mannose and galactose in a ratio of 4:6 (27.6 kDa). CME-1 was originally observed to exert a potent inhibitory
Wenfu Lu et al.
Oncotarget, 6(2), 771-788 (2015-01-19)
Aberrant elevation of JARID1B and histone H3 lysine 4 trimethylation (H3K4me3) is frequently observed in many diseases including prostate cancer (PCa), yet the mechanisms on the regulation of JARID1B and H3K4me3 through epigenetic alterations still remain poorly understood. Here we
J Boone Kauffman et al.
Ecological applications : a publication of the Ecological Society of America, 24(3), 518-527 (2014-05-20)
Mangroves are recognized to possess a variety of ecosystem services including high rates of carbon sequestration and storage. Deforestation and conversion of these ecosystems continue to be high and have been predicted to result in significant carbon emissions to the
John W Castellani et al.
Aviation, space, and environmental medicine, 85(4), 445-448 (2014-04-24)
It has been proposed that microclimate cooling systems exploit the peripheral extremities because of more efficient heat transfer. The purpose of this study was to quantify, using a patented microclimate cooling technique, the heat transfer from the plantar surface of
Andreas Svensson et al.
PloS one, 10(4), e0123553-e0123553 (2015-04-16)
Glioblastoma multiforme (GBM) is the most common brain tumor in adults. It presents an extremely challenging clinical problem, and treatment very frequently fails due to the infiltrative growth, facilitated by extensive angiogenesis and neovascularization. Pericytes constitute an important part of
T B Musso et al.
Environmental technology, 34(17-20), 2465-2476 (2014-02-18)
Earthen layers play a significant role in isolating contaminants in the subsurface, controlling the migration of contaminant plumes, and as landfill liners and covers. The physical, chemical and mineralogical properties of three calcareous mudstones from the Jagüel and Roca formations
Anna Gadaj et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 32(2), 180-193 (2014-11-06)
The depletion of three banned nitroimidazole drugs - dimetridazole (DMZ), metronidazole (MNZ) and ronidazole (RNZ) - was investigated in black tiger shrimp (Penaeus monodon) following in-water medication. The highest concentrations of residues were measured immediately after the 24-h immersion (d0).
Ching-Yao Tsai et al.
Carbohydrate polymers, 135, 308-315 (2015-10-11)
Oxidative damage to cornea can be induced by alkaline chemical burn which may cause vision loss or blindness. Recent studies showed that exogenous application of natural antioxidants may be a potential treatment for corneal wound healing. However, low ocular bioavailability
R Brooks et al.
Stem cells (Dayton, Ohio), 33(3), 848-858 (2014-11-18)
Promoting the expansion of adult stem cell populations offers the potential to ameliorate radiation or chemotherapy-induced bone marrow failure and allows for expedited recovery for patients undergoing these therapies. Previous genetic studies suggested a pivotal role for SH2 domain-containing inositol-5-phosphatase
Le Thi Hao et al.
Human molecular genetics, 24(2), 346-360 (2014-09-03)
Low levels of the survival motor neuron protein (SMN) cause the disease spinal muscular atrophy. A primary characteristic of this disease is motoneuron dysfunction and paralysis. Understanding why motoneurons are affected by low levels of SMN will lend insight into
Jessica A Reusch et al.
Journal of virology, 89(3), 1731-1743 (2014-11-21)
Epstein-Barr virus (EBV) maintains a lifelong latent infection within a subset of its host's memory B cells, while lytic EBV replication takes place in plasma cells and differentiated epithelial cells. Therefore, cellular transcription factors, such as BLIMP1, that are key
Mauricio Mora-Pale et al.
Biotechnology and bioengineering, 112(12), 2417-2428 (2015-06-26)
Plant polyphenols are known to have varying antimicrobial potencies, including direct antibacterial activity, synergism with antibiotics and suppression of bacterial virulence. We performed the in vitro oligomerization of resveratrol catalyzed by soybean peroxidase, and the two isomers (resveratrol-trans-dihydrodimer and pallidol)
Emanuele Claudio Latagliata et al.
Psychopharmacology, 231(21), 4099-4108 (2014-06-25)
Endogenous opioids could play a major role in the mesocorticolimbic dopamine (DA) responses to stress challenge. However, there is still no direct evidence of an influence of endogenous opioids on any of these responses. We assessed whether and how endogenous
Li Li et al.
Journal of nanoscience and nanotechnology, 14(6), 4313-4319 (2014-04-18)
Lutetium oxide nanocrystals codoped with Tm3+ and Yb3+ have been successfully synthesized via adjusting the pH values of the precursor solution in a hydrothermal method followed by a subsequent calcination process. The samples were systematically characterized by X-ray diffraction, field-emission
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