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Anastasiya M Kaneva et al.
Disease markers, 2015, 591454-591454 (2015-04-09)
The apolipoprotein (apo) B/apoA-I ratio represents the balance between apoB-rich atherogenic particles and apoA-I-rich antiatherogenic particles, and this ratio is considered to be a marker of cardiovascular risk. Although many studies have demonstrated the importance of the apoB/apoA-I ratio in
Laval Jacquin et al.
Genetics, selection, evolution : GSE, 46, 45-45 (2014-07-16)
Numerous methods have been developed over the last decade to predict allelic identity at unobserved loci between pairs of chromosome segments along the genome. These loci are often unobserved positions tested for the presence of quantitative trait loci (QTL). The
Cynthia Louis et al.
Journal of immunology (Baltimore, Md. : 1950), 195(1), 134-144 (2015-05-29)
M-CSF (or CSF-1) and GM-CSF can regulate the development and function of the mononuclear phagocyte system (MPS). To address some of the outstanding and sometimes conflicting issues surrounding this biology, we undertook a comparative analysis of the effects of neutralizing
Matthias Lenski et al.
Basic research in cardiology, 110(4), 40-40 (2015-05-29)
Atrial fibrillation (AF) is characterized by irregular contractions of atrial cardiomyocytes and increased energy demand. The aim of this study was to characterize the influence of arrhythmia on glucose and fatty acid (FA) metabolism in cardiomyocytes, mice and human left
Thomas H Fischer et al.
Cardiovascular research, 107(1), 184-196 (2015-05-21)
Enhanced cardiac late Na current (late INa) and increased sarcoplasmic reticulum (SR)-Ca(2+)-leak are both highly arrhythmogenic. This study seeks to identify signalling pathways interconnecting late INa and SR-Ca(2+)-leak in atrial cardiomyocytes (CMs). In murine atrial CMs, SR-Ca(2+)-leak was increased by
Hongwei Yu et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(42), 14086-14102 (2015-10-23)
The sensation of touch is initiated when fast conducting low-threshold mechanoreceptors (Aβ-LTMRs) generate impulses at their terminals in the skin. Plasticity in this system is evident in the process of adaption, in which a period of diminished sensitivity follows prior
Yueer Yan et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(34), 12161-12170 (2015-07-16)
A clear and deep understanding of zeolite crystallization with the addition of organosilane is desirable for the reasonable design and preparation of hierarchical zeolites. Herein, the effects of different organosilanes on zeolite crystallization were systematically studied. It was found that
S Kar et al.
Biochimica et biophysica acta, 1840(11), 3264-3276 (2014-08-05)
Microbial resistance to antibiotics has triggered the development of nanoscale materials as an alternative strategy. To stabilize these particles an inert support is needed. Porous nanomullite developed by sol-gel route is loaded with copper and silver nanoparticle by simple adsorption
Hodaka Oki et al.
Journal of magnetic resonance imaging : JMRI, 41(1), 125-131 (2013-11-26)
To compare the MR findings including diffusion-weighted imaging (DWI) between symptomatic and asymptomatic patients with autoimmune pancreatitis (AIP) and to determine whether DWI can be used as an objective biomarker for symptomatic AIP, which is considered an indication for steroid
John Shorter et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(27), E3555-E3563 (2015-06-24)
Aggression is an evolutionarily conserved complex behavior essential for survival and the organization of social hierarchies. With the exception of genetic variants associated with bioamine signaling, which have been implicated in aggression in many species, the genetic basis of natural
M Vrablík et al.
Physiological research, 63(6), 743-752 (2014-08-27)
Obesity is a strong cardiometabolic (CM) risk factor in children. We tested potential CM risk in obese/overweight children and the effect of an intensive lifestyle intervention using newer CM markers: atherogenic index of plasma AIP [Log(TG/HDL-C)], apoB/apoAI ratio and a
Selvedin Telalović et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 17(7), 2077-2088 (2011-01-25)
Bimetallic three-dimensional amorphous mesoporous materials, Al-Zr-TUD-1 materials, were synthesised by using a surfactant-free, one-pot procedure employing triethanolamine (TEA) as a complexing reagent. The amount of aluminium and zirconium was varied in order to study the effect of these metals on
Melissa Lamar et al.
Current Alzheimer research, 12(7), 640-647 (2015-08-05)
Metabolic syndrome (MetS), i.e., meeting criteria for any three of the following: hyperglycemia, hypertension, hypertriglyceridemia, low high-density lipoprotein and/or abdominal obesity, is associated with negative health outcomes. For example, MetS negatively impacts cognition; however, less is known about incremental MetS
Qinjie Zhou et al.
The Journal of biological chemistry, 290(23), 14729-14739 (2015-04-26)
The transcription factor IRF7 (interferon regulatory factor 7) is a key regulator of type I interferon and plays essential roles in restricting virus infection and spread. IRF7 activation is tightly regulated to prevent excessive inflammation and autoimmunity; however, how IRF7
Malwina Czerwińska et al.
Materials (Basel, Switzerland), 13(17) (2020-09-06)
Prostate cancer is the second most frequent malignancy in men worldwide. Unfortunately, current therapies often lead to the onset of metastatic castration-resistant prostate cancer (mCRPC), causing significant mortality. Therefore, there is an urgent need for new and targeted therapies that
Jiancong Liu et al.
Science advances, 3(5), e1603171-e1603171 (2017-06-01)
Thermally activated delayed fluorescence (TADF) materials are inspiring intensive research in optoelectronic applications. To date, most of the TADF materials are limited to metal-organic complexes and organic molecules with lifetimes of several microseconds/milliseconds that are sensitive to oxygen. We report
Julia Bischof et al.
PloS one, 10(9), e0136298-e0136298 (2015-09-02)
The mouse strain MRL/MpJ is prone to spontaneously develop autoimmune pancreatitis (AIP). To elucidate the genetic control towards the development of the phenotype and to characterize contributions of immunocompetent cell types, MRL/MpJ mice were interbred with three additional strains (BXD2/TYJ
K Kinoshita et al.
Physical chemistry chemical physics : PCCP, 17(28), 18705-18709 (2015-06-30)
The influence of the structure of ionic liquids on the crystallinity of aluminum hydroxide (Al(OH)3) prepared by a sol-gel process with aluminum isopropoxide (Al(OPr(i))3) in imidazolium-based ionic liquids was investigated. When Al(OH)3 was prepared in ionic liquids having long alkyl
Takataro Fukuhara et al.
Biochemical and biophysical research communications, 463(4), 968-974 (2015-06-10)
The serine/threonine kinase Mst1 plays important roles in the control of immune cell trafficking, proliferation, and differentiation. Previously, we reported that Mst1 was required for thymocyte selection and regulatory T-cell functions, thereby the prevention of autoimmunity in mice. In humans
James Bonaiuto et al.
Biological cybernetics, 109(6), 639-669 (2015-11-21)
The activity of certain parietal neurons has been interpreted as encoding affordances (directly perceivable opportunities) for grasping. Separate computational models have been developed for infant grasp learning and affordance learning, but no single model has yet combined these processes in
Shin Hamada et al.
Digestion, 91(4), 263-271 (2015-04-15)
Autoimmune pancreatitis (AIP) is a rare disease that has recently emerged as a unique type of pancreatitis with a presumed autoimmune etiology. MicroRNA (miRNA) is a small non-coding RNA that targets multiple mRNAs. miRNAs might exist in serum in a
Albert Beckers et al.
Endocrine-related cancer, 22(3), 353-367 (2015-02-26)
X-linked acrogigantism (X-LAG) is a new syndrome of pituitary gigantism, caused by microduplications on chromosome Xq26.3, encompassing the gene GPR101, which is highly upregulated in pituitary tumors. We conducted this study to explore the clinical, radiological, and hormonal phenotype and
Yonglan He et al.
Abdominal imaging, 40(8), 3104-3116 (2015-08-20)
To discuss the diverse imaging features of pancreatic and extra-pancreatic lesions of IgG4-related disease (IgG4-RD) on multi-detector CT (MDCT). This retrospective study was approved by our institutional research ethics board, and informed consent was waived. From 2008 to 2013, 159
Bradley O Elmore et al.
PloS one, 10(5), e0125027-e0125027 (2015-05-06)
Serum lipoproteins (LP) are increasingly being recognized as dual purpose molecules that contribute to both cholesterol homeostasis and host innate defense. In fact, very low LP levels are associated with increased risk of bacterial infection in critically ill patients. In
Xuelei Wang et al.
Materials (Basel, Switzerland), 13(7) (2020-04-15)
Four metal phosphites/phosphates crystal materials C8N4H34Al2P4O18 (1), C3N2H17GaP2O8 (2), H5In2P3O10 (3), and H9In2P3O13 (4) have been solvothermally synthesized by organic amines in the presence of mixed solvents. Structural analyses indicate that compound 1 and 2 show one-dimensional (1D) chain structures;
Zhehao Huang et al.
Nature communications, 11(1), 3762-3762 (2020-07-30)
Zeolites have unique pore structures of molecular dimensions and tunable compositions, making them ideal for shape selective catalysis and separation. However, targeted synthesis of zeolites with new pore structures and compositions remains a key challenge. Here, we propose an approach
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