Search Within
Applied Filters:
Showing 1-30 of 880 results for "


" within Papers
Dan Shi et al.
Journal of cellular and molecular medicine, 18(10), 1992-1999 (2014-08-06)
Ischaemic cardiac arrhythmias cause a large proportion of sudden cardiac deaths worldwide. The ischaemic arrhythmogenesis is primarily because of the dysfunction and adverse remodelling of sarcolemma ion channels. However, the potential regulators of sarcolemma ion channel turnover and function in
Javier Gandasegui et al.
PLoS neglected tropical diseases, 9(7), e0003963-e0003963 (2015-08-01)
Urogenital schistosomiasis due to Schistosoma haematobium is a serious underestimated public health problem affecting 112 million people - particularly in sub-Saharan Africa. Microscopic examination of urine samples to detect parasite eggs still remains as definitive diagnosis. This work was focussed
Julia C Frei et al.
Virology, 485, 371-382 (2015-09-05)
Here we investigated the binding of Dengue virus envelope glycoprotein domain III (DIII) by two broadly neutralizing antibodies (bNAbs), 4E11 and 4E5A. There are four serotypes of Dengue virus (DENV-1 to -4), whose DIII sequences vary by up to 49%.
Diana Balasubramanian et al.
Neuropharmacology, 99, 79-88 (2015-07-08)
Valproic acid (VPA) is a widely used antiepileptic drug and first-line treatment in bipolar disorder, although the mechanisms underlying its therapeutic effects are largely unknown. Recently, the recognition of VPA as an epigenetic drug offers new opportunities for understanding its
Peidong Han et al.
Cell research, 24(9), 1091-1107 (2014-08-16)
While the adult human heart has very limited regenerative potential, the adult zebrafish heart can fully regenerate after 20% ventricular resection. Although previous reports suggest that developmental signaling pathways such as FGF and PDGF are reused in adult heart regeneration
D Joon et al.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 19(8), 986-991 (2015-07-15)
The main challenge in combatting extra-pulmonary tuberculosis (EPTB) is the lack of a rapid, reliable and inexpensive diagnostic test for the detection of Mycobacterium tuberculosis. To evaluate the diagnostic potential of an L-serine dehydratase gene (sdaA) loop-mediated isothermal amplification (LAMP)
Judith Taibon et al.
Journal of agricultural and food chemistry, 63(23), 5707-5713 (2015-05-26)
The entomopathogenic fungus Metarhizium brunneum is widely applied as a biological pest control agent. Consequently, its use has to be accompanied by a risk management approach, which includes the need to monitor the fate of its bioactive metabolites in the
Dhirapatara Charoenvidhya et al.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 96(4), 395-398 (2013-05-23)
To compare the percentages of pregnant women with preeclampsia who reached the therapeutic serum magnesium levels between those who received maintenance magnesium sulfate infusion of 2 g/hour versus I g/hour Sixty women diagnosed of preeclampsia and magnesium sulfate that were
Eri Yamauchi et al.
Asian-Australasian journal of animal sciences, 28(8), 1084-1089 (2015-06-25)
Chemerin, highly expressed in adipose and liver tissues, regulates glucose and lipid metabolism and immunity in these tissues in ruminants and mice. Our previous reports showed that chemerin is involved in adipogenesis and lipid metabolism in adipose tissue as an
E O Adewoye et al.
African journal of medicine and medical sciences, 41(4), 373-378 (2013-05-16)
Many gastrointestinal complications in diabetes are connected to neurohumoral dysfunction resulting in abnormalities of intestinal motility, secretion and absorption. Minerals have been reported as essential cofactors for basic cellular reactions but there is dearth of information on effect of Magnesium
Xue Feng et al.
Journal of separation science, 38(17), 3047-3054 (2015-06-23)
A new method for simultaneous determination of 36 pesticides, including 15 organophosphorus, six carbamate, and some other pesticides in soil was developed by liquid chromatography with tandem quadruple linear ion trap mass spectrometry. The extraction and clean-up steps were optimized
Corinne Caillaud et al.
The Journal of endocrinology, 225(2), 77-88 (2015-03-15)
Erythropoietin (EPO) ameliorates glucose metabolism through mechanisms not fully understood. In this study, we investigated the effect of EPO on glucose metabolism and insulin signaling in skeletal muscle. A 2-week EPO treatment of rats fed with a high-fat diet (HFD)
Derek S Boeldt et al.
The Journal of endocrinology, 223(1), 1-11 (2014-07-27)
In pregnancy, the uterine vasculature undergoes dramatic vasodilatory adaptations. Previously, vascular endothelial growth factor (VEGF) has been shown to stimulate endothelial nitric oxide synthase (eNOS) in uterine artery endothelial cells (UAECs) derived from pregnant ewes to a greater extent than
Mei Li et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(22), 7458-7471 (2014-05-30)
TP53-induced glycolysis and apoptosis regulator (TIGAR) inhibits glycolysis and increases the flow of pentose phosphate pathway (PPP), which generates NADPH and pentose. We hypothesized that TIGAR plays a neuroprotective role in brain ischemia as neurons do not rely on glycolysis
Muneki Ikeda et al.
The Journal of endocrinology, 226(2), M13-M27 (2015-06-03)
The corticosterone (CORT) level changes along the circadian rhythm. Hippocampus is sensitive to CORT, since glucocorticoid receptors are highly expressed. In rat hippocampus fixed in a living state every 3 h, we found that the dendritic spine density of CA1 pyramidal
Isaac Mutingwende et al.
Journal of microbiological methods, 116, 37-43 (2015-06-21)
Global tuberculosis (TB) control and eradication is hampered by the unavailability of simple, rapid and affordable diagnostic tests deployable at low infrastructure microscopy centers. We have developed and evaluated the performance of a nucleic acid amplification test for detection of
Oluwakemi Badaki-Makun et al.
Pediatric blood & cancer, 61(6), 1049-1054 (2014-01-21)
Multiple recent Sickle Cell Disease studies have been terminated due to poor enrollment. We developed methods to overcome past barriers and utilized these to study the efficacy and safety of intravenous magnesium for vaso-occlusive crisis (VOC). We describe the methods
Marion Gabel et al.
The Journal of cell biology, 210(5), 785-800 (2015-09-02)
Annexin A2, a calcium-, actin-, and lipid-binding protein involved in exocytosis, mediates the formation of lipid microdomains required for the structural and spatial organization of fusion sites at the plasma membrane. To understand how annexin A2 promotes this membrane remodeling
Kartheyaene Jayaprakash et al.
BMC microbiology, 14, 193-193 (2014-07-20)
Porphyromonas gingivalis is an important bacterial etiological agent involved in periodontitis. The bacterium expresses two kinds of cysteine proteases called gingipains: arginine gingipains (RgpA/B) and lysine gingipain (Kgp). This study evaluated the interaction between P. gingivalis and THP-1 cells, a
Jeroen H F de Baaij et al.
Physiological reviews, 95(1), 1-46 (2014-12-30)
Magnesium (Mg(2+)) is an essential ion to the human body, playing an instrumental role in supporting and sustaining health and life. As the second most abundant intracellular cation after potassium, it is involved in over 600 enzymatic reactions including energy
Duraisamy Ponnusamy et al.
Infection and immunity, 83(5), 2065-2081 (2015-03-11)
The identification of new virulence factors in Yersinia pestis and understanding their molecular mechanisms during an infection process are necessary in designing a better vaccine or to formulate an appropriate therapeutic intervention. By using a high-throughput, signature-tagged mutagenic approach, we
H Qu et al.
Journal of animal science, 93(8), 3832-3842 (2015-10-07)
Heat stress (HS) results from excessive heat load on animals such that all adaptive mechanisms used to dissipate the heat do not return the body to normal body temperature. In pigs, HS results in increased fat deposition compared with pair-fed
Rafael Prados-Rosales et al.
Journal of agricultural and food chemistry, 63(33), 7326-7332 (2015-08-06)
Many of the most widely consumed edible mushrooms are pigmented, and these have been associated with some beneficial health effects. Nevertheless, the majority of the reported compounds associated with these desirable properties are non-pigmented. We have previously reported that melanin
Ersilia Cipolletta et al.
PloS one, 10(6), e0130477-e0130477 (2015-06-26)
Activation of Ca2+/Calmodulin protein kinase II (CaMKII) is an important step in signaling of cardiac hypertrophy. The molecular mechanisms by which CaMKII integrates with other pathways in the heart are incompletely understood. We hypothesize that CaMKII association with extracellular regulated
Ketsarin Seebunrueng et al.
Talanta, 132, 769-774 (2014-12-06)
A simple and rapid microextraction method, vortex-assisted low density solvent liquid-liquid microextraction and salt-induced demulsification (VLLME-SID) coupled to high performance liquid chromatography (HPLC) was developed for the determination of organophosphorus pesticide (OPP) residues in fruits. The studied OPPs were azinphos-methyl
Dalyir I Pretto et al.
Journal of medical genetics, 52(1), 42-52 (2014-11-02)
Over 40% of male and ∼16% of female carriers of a premutation FMR1 allele (55-200 CGG repeats) will develop fragile X-associated tremor/ataxia syndrome, an adult onset neurodegenerative disorder, while about 20% of female carriers will develop fragile X-associated primary ovarian insufficiency.
Siham Fellahi et al.
Virology journal, 12, 116-116 (2015-08-05)
Infectious bronchitis virus (IBV), a major pathogen of commercial poultry flocks, circulates in the form of several serotypes/genotypes. Only a few amino-acid changes in the S1 subunit of wild-type IBVS proteins may result in mutants unaffected by current vaccines. Partial
Ajoy Saha et al.
Journal of food science and technology, 52(7), 4001-4014 (2015-07-04)
This paper reports a simple and rapid method for simultaneous determination of the residues of selected herbicides viz. pendimethalin, oxyfluorfen, imazethapyr and quizalofop-p-ethyl in peanut by liquid chromatography-tandem mass spectrometry (LC-MS/MS). A modified approach of the QuEChERS methodology was used
Zbynek Dzuman et al.
Analytica chimica acta, 863, 29-40 (2015-03-04)
A new reliable and highly sensitive method based on high performance liquid chromatographic (HPLC) separation and high resolution tandem mass spectrometric detection (HRMS/MS) has been developed and validated for determination of 323 pesticide residues, 55 mycotoxins, and 11 plant toxins
Priya Saini et al.
Environmental monitoring and assessment, 187(8), 541-541 (2015-08-01)
A study was undertaken to evaluate the decline of the residues of pyridalyl in tomatoes grown in two different cultivation systems: open field (conventional cultivation) and net house (pot experiment). Field experiment was conducted with commercial (10 EC) and nanoformulation
Page 1 of 30
Page 1 of 30