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103-90-2

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Ji-Young Park et al.
Journal of clinical pharmacology, 46(1), 109-114 (2006-01-07)
The authors evaluated the effect of high-dose aspirin at a therapeutic dose, using chlorzoxazone as a probe for CYP2E1 enzyme activity. In a randomized, open-label, 2-way crossover study, 10 healthy men were treated 3 times daily for 6 days with...
Edward T Bagu et al.
Journal of molecular endocrinology, 47(3), 299-313 (2011-10-06)
Hepcidin is an antimicrobial peptide hormone involved in the metabolism of iron, encoded for by the HAMP gene mainly in hepatocytes. It's expressed at lower levels in other cells such as the macrophages. The mechanisms that determine tissue-specific expression of...
Yong-mei Zhu et al.
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 28(6), 371-374 (2007-10-18)
To analyze the mutation of FLT3 internal tandem duplication (FLT3-ITD) in bone marrow cells from patients with newly-diagnosed acute promyelocytic leukemia (APL). The mutation of FLT3-ITD in bone marrow mononuclear cells (MNCs) from 103 APL patients were screened by polymerase...
Maria M Traczewski et al.
Antimicrobial agents and chemotherapy, 52(11), 3863-3867 (2008-08-30)
Retapamulin, the first pleuromutilin antimicrobial agent approved for the topical treatment of skin infections in humans, was tested against 987 clinical isolates representing 30 species and/or resistance groups. MICs were determined along with disk diffusion zone diameters using a 2-microg...
J G Wilcox et al.
Fertility and sterility, 66(5), 748-752 (1996-11-01)
To determine the independent biologic effects of 17 alpha-dihydroequilin sulfate. Prospective randomized study. University of Southern California Medical Center. Twenty-one postmenopausal women, mean age 50 +/- 2 (+/-SEM) years, and mean body mass index 27 +/- 2. Women were randomized...
Keiko Satoh et al.
Genes to cells : devoted to molecular & cellular mechanisms, 7(2), 187-197 (2002-03-16)
The postsynaptic density (PSD) at synapses is a specialized submembranous structure where neurotransmitter receptors are linked to cytoskeleton and signalling molecules. Activity-dependent dynamic change in the components of the PSD is a mechanism of synaptic plasticity. Identification of the PSD...
S Thomas et al.
Bone and mineral, 8(1), 1-6 (1990-01-01)
The mechanism of the acute hypocalcemia that follows acute ethanol administration has not been established. Measurements of parathyroid hormone (PTH) performed during this hypocalcemia reveal conflicting results. We compared the response of ionized calcium (Ca2+), immunoreactive PTH and bone Gla...
Imen Arfa et al.
Journal of the renin-angiotensin-aldosterone system : JRAAS, 9(1), 32-36 (2008-04-12)
The aim of the present study was to investigate whether the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism is associated with diabetic nephropathy and type 2 diabetes in the Tunisian population. A case-control study was conducted among 141 unrelated type 2...
Dengfeng Cao et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(2), 288-296 (2010-11-09)
LIN28 has been shown to have an important role in primordial germ cell development and malignant transformation of germ cells in mouse. In this study, we examined the immunohistochemical profile of LIN28 in 131 primary human extragonadal germ cell tumors...
J Körkkö et al.
American journal of human genetics, 62(1), 98-110 (1998-03-07)
Although >90% of patients with osteogenesis imperfecta (OI) have been estimated to have mutations in the COL1A1 and COL1A2 genes for type I procollagen, mutations have been difficult to detect in all patients with the mildest forms of the disease...
Jie Tian et al.
Journal of separation science, 35(1), 145-152 (2011-12-07)
In this paper, two methods based on organic solvent dispersive liquid-liquid microextraction (OS-DLLME) and ionic liquid dispersive liquid-liquid microextraction (IL-DLLME) coupled with high-performance liquid chromatography have been critically compared for analyzing emodin and its metabolites (aloe-emodin, anthraquinone-2-carboxylic acid, rhein, danthron...
Graciela Stalldecker et al.
Pituitary, 13(4), 345-350 (2010-08-03)
The aim of the study is to assess the rate of any potential adverse effects on women who became pregnant under cabergoline (CAB) treatment and to evaluate any effects on the embryo-fetal development and on children who were born from...
C A Rivers et al.
Molecular and cellular endocrinology, 160(1-2), 51-59 (2000-03-15)
Several variants (V1-V8) have been described for the 5' untranslated region of human growth hormone receptor cDNA (Pekhletsky, R.I., Chernov B.K., Rubtsov, P.M., 1992. Variants of the 5'-untranslated sequence of human growth hormone receptor mRNA. Mol. Cell. Endocrinol. 90, 103-109)....
Michelangelo Pascale et al.
Talanta, 89, 231-236 (2012-01-31)
European intake estimates indicate that the presence of HT-2 and T-2 toxins in cereals, mainly in oats, can be of concern for human health. Therefore, the development of sensitive, rapid and reliable methods for determining these mycotoxins in cereals, in...
Ting-Ting Zhang et al.
The Journal of allergy and clinical immunology, 122(4), 811-819 (2008-11-19)
Recent studies indicate that pharmaceutical blockade of phosphoinositide 3-kinase (PI3K) signaling enzymes might be effective in reducing allergic airway inflammation. Signals generated by the p110delta PI3K isoform play critical roles in signaling through antigen and cytokine receptors and were shown...
J Wu et al.
Radiation protection dosimetry, 152(1-3), 119-124 (2012-08-28)
Monte Carlo (MC) simulation has been commonly used in the dose evaluation of radiation accidents and for medical purposes. The accuracy of simulated results is affected by the particle-tracking algorithm, cross-sectional database, random number generator and statistical error. The differences...
Z R Chen et al.
British journal of clinical pharmacology, 31(4), 381-390 (1991-04-01)
1. The pharmacokinetics, metabolism and partial clearances of codeine to morphine, norcodeine and codeine-6-glucuronide after single (30 mg) and chronic (30 mg 8 h for seven doses) administration of codeine were studied in eight subjects (seven extensive and one poor...
S Ameli-Renani et al.
Cardiovascular and interventional radiology, 38(5), 1137-1142 (2015-07-15)
To evaluate the technical success and mid-term outcomes following transcatheter embolisation of type 1a endoleak after Nellix endovascular aneurysm sealing (EVAS). Seven patients (5 men; mean age 83; range 79-90) underwent transcatheter embolisation between July 2013 and August 2014. The...
Dexter L Lee et al.
Hypertension (Dallas, Tex. : 1979), 44(3), 259-263 (2004-08-04)
This study tested the hypothesis that the inflammatory cytokine, interleukin-6, contributes to the hypertensive response to acute psychosocial stress, caused by switching male mice to a cage previously occupied by a different male mouse. Male C57BL6 (WT) and interleukin-6 (IL-6)...
Ana Catarina Alves et al.
Talanta, 146, 369-374 (2015-12-24)
A low-pressure liquid chromatography system for the on-line quantification of caffeine loaded into lipid nanoparticles that permeates pig skin was developed. The apparatus includes a Franz diffusion cell with computer-controlled sampling that allows collection of acceptor solution with automatic compensation...
Clarissa C Koga et al.
Journal of food science, 80(9), S2064-S2070 (2015-08-04)
Resveratrol is a polyphenol that is associated with numerous health benefits related to heart disease, cancer, diabetes, and neurological function. The addition of this compound to food products would help to deliver these health benefits to the consumer. However, bitterness...
J Cuervo-Arango et al.
Theriogenology, 84(6), 1003-1013 (2015-07-06)
The present study characterizes the relationship between the levels of eCG, ovarian morphology, resumption of cyclicity, and fertility in postaborted embryo transfer recipient mares. A total of 32 pregnant recipient mares carrying a male fetus were aborted at approximately 65...
Britta Polentarutti et al.
The Journal of pharmacy and pharmacology, 62(4), 462-469 (2010-07-08)
The aim was to compare the ability of pretreatments to consistently adjust gastric conditions to low or high pH in the fasted state in dogs. Four male Labrador/Labrador-cross dogs weighing 25-35 kg were surgically equipped with a ventricle fistula cannula...
Edgar Turner Overton et al.
Annals of internal medicine, 162(12), 815-824 (2015-06-16)
Antiretroviral therapy initiation for HIV-1 infection is associated with 2% to 6% loss of bone mineral density (BMD). To evaluate the effect of vitamin D3 plus calcium supplementation on bone loss associated with antiretroviral therapy initiation. 48-week prospective, randomized, double-blind...
Gemma Villuendas et al.
Human reproduction (Oxford, England), 20(11), 3184-3191 (2005-07-23)
We aimed to evaluate the influence of the Gly972Arg variant of the insulin receptor substrate-1 gene (IRS-1) and the Gly1057Asp variant in IRS-2 on insulin resistance and glucose tolerance in women with polycystic ovary syndrome (PCOS) and healthy controls. Genotypes...
Juan A Ramos Guivar et al.
Talanta, 141, 307-314 (2015-05-13)
Magnetic nanoparticles have been applied in many areas of nanomedicine. Sensing platforms based on this type of nanoparticles have received attention due to the relative low cost and biocompatibility. Biosensor is the most widely investigated type of analytical device. This...
Dengfeng Cao et al.
Human pathology, 42(5), 710-718 (2011-02-04)
LIN28 is an RNA-binding protein involved in maintaining the pluripotency of embryonic stem cells. Using formalin-fixed, paraffin-embedded tissue blocks, we performed immunohistochemical staining of LIN28 in 103 primary and 81 metastatic testicular germ cell tumors (54 intratubular germ cell neoplasias...
Lin Lu et al.
Clinical biochemistry, 40(11), 810-816 (2007-05-15)
This study aimed to determine whether elevated serum levels of glycated albumin, high-sensitivity C-reactive protein (hsCRP) and tumor necrosis factor (TNF)-alpha were related to an increased risk for coronary artery disease (CAD) and renal insufficiency in patients with type 2...
Thomas Kelleher et al.
Blood cells, molecules & diseases, 33(1), 35-39 (2004-06-30)
Homozygosity for a cysteine to tyrosine translocation at position 282 within the HFE gene (C282Y) is responsible for over 90% of hereditary hemochromatosis (HH) in Celtic populations. Determining those C282Y homozygotes at greatest risk for iron overload is a major...
Daniel Heinrichs et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(12), 5136-5147 (2014-08-15)
MIF is an inflammatory cytokine but is hepatoprotective in models of hepatotoxin-induced liver fibrosis. Hepatic fibrosis can also develop from metabolic liver disease, such as nonalcoholic fatty liver disease (NASH). We investigated the role of MIF in high-fat or methionine-...
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