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20224AST

Supelco

Astec® CYCLOBOND I 2000 SP Chiral HPLC Column

5 μm particle size, L × I.D. 25 cm × 4.6 mm

eCl@ss:
32110501
NACRES:
SB.52

material

stainless steel column

Quality Level

product line

Astec®

packaging

pkg of 1 ea

manufacturer/tradename

Astec®

parameter

0-50 °C temperature
172 bar pressure (2500 psi)

technique(s)

HPLC: suitable
LC/MS: suitable

L × I.D.

25 cm × 4.6 mm

matrix

silica particle platform
fully porous particle

matrix active group

cyclodextrin, beta- phase

particle size

5 μm

pore size

100 Å

operating pH

3.5-7

separation technique

chiral

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General description

On CYCLOBOND I 2000 SP, the hydroxyl groups on the surface of the β-cyclodextrin have been reacted with (S)-propylene oxide. This has the effect of extending hydrogen-bonding capabilities to accommodate analytes with chiral centers that are relatively distant from an aromatic ring structure. The (S)- form shows enhanced selectivity and efficiency for some separations, methadone, for example.

  • Bonded phase: (S)-Hydroxypropyl modified β-cyclodextrin

Resources:
CYCLOBOND FAQs
CYCLOBOND Reference Bibliography
Chiral Product Literature

Other Notes

Recommended alternative 20024AST ASTEC® CYCLOBOND 2000 Chiral HPLC Column
See technical report

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Legal Information

Astec is a registered trademark of Sigma-Aldrich Co. LLC
CYCLOBOND is a trademark of Sigma-Aldrich Co. LLC

Certificate of Analysis

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Certificate of Origin

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