SML1604

NDB

≥98% (HPLC)

• Synonym(s): Benzamide, 2,6-dichloro-4-(dimethylamino)-N-[3-(1,1-dimethylethyl)-4-hydroxyphenyl]-N-(phenylmethyl)-, N-Benzyl-N-(3-tert-butyl-4-hydroxy-phenyl)-2,6-dichloro-4-dimethylamino-benzamide
• Empirical Formula (Hill Notation): C₂₆H₂₈Cl₂N₂O₂
• CAS Number: 1660153-08-1
• Molecular Weight: 471.42
• UNSPSC Code: 51111800
• PubChem Substance ID: 329825490
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CN(C)C1=CC(Cl)=C(C(N(CC2=CC=CC=C2)C3=CC(C(C)(C)C)=C(O)C=C3)=O)C(Cl)=C1
• InChI: 1S/C26H28Cl2N2O2/c1-26(2,3)20-13-18(11-12-23(20)31)30(16-17-9-7-6-8-10-17)25(32)24-21(27)14-19(29(4)5)15-22(24)28/h6-15,31H,16H2,1-5H3
• InChI key: IDACWMHIKWNAEO-UHFFFAOYSA-N

Description

Biochem/physiol Actions

NDB is a selective antagonist of human Farnesoid X receptor α (FXRα) that effectively modulates FXRα down-stream genes.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable