Influenza virus hemagglutinin (HA) precursor is encoded by the gene mapped on segment 4. The encoded protein is a 76KDa surface glycoprotein and it exists as trimers on the envelope.
Recombinant Fc fusion protein corresponding to amino acids 17-531 of virus HA (Influenza A virus, A/Viet Nam/3062/2004 (H5N1))
Influenza virus hemagglutinin (HA) acts as a key immunogen in avian influenza virus (AIV) vaccines. Activated HA facilitates virus attachment to oligosaccharide receptors on host cell surface and is involved in penetration through fusion following conformational modifications in the endolysosomal compartment. 226 and 228 residues in hemagglutinin (HA) of the H3 subtype plays a key role in host range restriction and receptor specificity. Influenza virus hemagglutinin (HA) is responsible for 1918 influenza pandemic.
Solution in phosphate buffered saline, pH 7.4