PHG0003

MES hydrate

• Synonym(s): 2-(N-Morpholino)ethanesulfonic acid hydrate, 4-Morpholineethanesulfonic acid
• Empirical Formula (Hill Notation): C₆H₁₃NO₄S · xH₂O
• CAS Number: 1266615-59-1
• Molecular Weight: 195.24 (anhydrous basis)
• MDL number: MFCD00149409
• PubChem Substance ID: 329823021
• NACRES: NA.21

Properties

• biological source: synthetic
• Quality Level: 400
• form: powder
• technique(s): cell culture | mammalian: suitable
• impurities: Endotoxin, microbial, and trace metals; tested
• useful pH range: 5.5-6.7
• pKa: 6.1
• suitability: suitable for manufacturing use
• foreign activity: Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
• SMILES string: O.OS(=O)(=O)CCN1CCOCC1
• InChI: 1S/C6H13NO4S.H2O/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);1H2
• InChI key: MIIIXQJBDGSIKL-UHFFFAOYSA-N

Description

Packaging

100 g in poly bottle

5, 25, 50 kg in poly drum

1 kit

Application

MES is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for medias and protein based buffer formulations to maintain a stable environment in solution. MES is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.

MES is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream), and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable