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P1750

Sigma-Aldrich

Pancreatin from porcine pancreas

4 × USP specifications

Synonym(s):
Pancreatin from hog pancreas
CAS Number:
EC Number:
MDL number:
NACRES:
NA.54

Agency

USP (specifications)

Quality Level

form

powder

specific activity

4 × USP specifications

contains

lactose or sucrose as extender (The sucrose used might contain up to 3.25% starch.)

storage temp.

−20°C

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Application

Pancreatin from porcine pancreas has been used:
  • for a study to assess the treatment of steatorrhea by lipase supplementation therapy
[78]
  • for a study to investigate treatment options for pancreatic diabetes in patients experiencing the decompensated stage of chronic pancreatitis
  • [88]
  • to safely and effectively remove formalin-fixed tissues from arterial grafts without causing structural damage and loss in fiber integrity
  • [36]
  • to assess cleavage by digestive enzymes.
  • for in vitro digestibility analysis and to test the sensitivities of cellulolytic bacteria inhibitors.
  • [27]
  • along with amyloglucosidase for the in vitro digestion of starch in food samples.
  • [45]

    Packaging

    25, 100, 500 g in poly bottle

    Biochem/physiol Actions

    Pancreatin contains enzymatic components including trypsin, amylase and lipase, ribonuclease, and protease, produced by the exocrine cells of the porcine pancreas. This combination of enzymes allows it to hydrolyze proteins, starch and fats. Pancreatin will convert not less than 25 times its weight of potato starch into soluble carbohydrates in 5 minutes in water at 40°C, will digest not less than 25 times its weight of casein in 60 minutes at pH 7.5 at 40°C and will release not less than microequivalents of acid per min per mg pancreatin from olive oil at pH 9.0 at 37°C.

    Pictograms

    Exclamation markHealth hazard

    Signal Word

    Danger

    Hazard Classifications

    Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

    Target Organs

    Respiratory system

    Storage Class Code

    11 - Combustible Solids

    WGK

    WGK 2

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

    Certificate of Analysis

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    Certificate of Origin

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