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N1514

Sigma-Aldrich

Nervonic acid

≥99% (capillary GC)

Synonym(s):
cis-15-Tetracosenoic acid, Selacholeic acid
Linear Formula:
CH3(CH2)7CH=CH(CH2)13COOH (cis)
CAS Number:
Molecular Weight:
366.62
Beilstein:
1728551
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

biological source

plant

assay

≥99% (capillary GC)

form

powder

mp

42-43 °C (lit.)

functional group

carboxylic acid

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCC\C=C/CCCCCCCCCCCCCC(O)=O

InChI

1S/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9-

InChI key

GWHCXVQVJPWHRF-KTKRTIGZSA-N

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Application

Nervonic acid has been used as a synthetic lipid supplement in vitro to study about effect of the developmental diet in Drosophila lifespan.

Packaging

100 mg in ampule
Sealed ampule.

Biochem/physiol Actions

Nervonic acid (C24:1), a component of membrane sphingolipids and phosphatidylethanolamines, may be a useful predictor of chronic kidney disease mortality and diabetes. Nervonic acid oils are being studied for pharmaceutical, nutraceutical and industrial applications. Nervonic acid is a major component of Lunaria oil.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Gregory C Shearer et al.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 22(2), 277-283 (2011-07-22)
Although the value of red blood cell fatty acids (FAs) in estimating risk for acute coronary syndrome in the general population is evident, the value of FAs in chronic kidney disease (CKD) is unknown. Here, we provide a pilot analysis
Martin Karlsson et al.
Obesity (Silver Spring, Md.), 14(11), 1931-1939 (2006-12-01)
Fatty acid (FA) composition has a role in adipogenesis. The objective was to study serum phospholipid (PL) FAs in adolescents and their relation to abdominal adipose tissue (AT) compartments and metabolic markers. Abdominal AT was measured by magnetic resonance imaging
Todd E Fox et al.
Journal of lipid research, 52(3), 509-517 (2010-11-12)
Alterations in lipid metabolism may contribute to diabetic complications. Sphingolipids are essential components of cell membranes and have essential roles in homeostasis and in the initiation and progression of disease. However, the role of sphingolipids in type 1 diabetes remains
Yiming Guo et al.
Plant molecular biology, 69(5), 565-575 (2008-12-17)
Nervonic acid is a Very Long-Chain Monounsaturated Fatty Acid (VLCMFA), 24:1 Delta15 (cis-tetracos-15-enoic acid) found in the seed oils of Lunaria annua, borage, hemp, Acer (Purpleblow maple) and Tropaeolum speciosum (Flame flower). However, of these, only the "money plant" (Lunaria
Developmental diet regulates Drosophila lifespan via lipid autotoxins
Stefana MI, et al.
Nature Communications, 8(1), 1384-1384 (2017)

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