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H4511

Sigma-Aldrich

Serotonin hydrogen maleate

powder

Synonym(s):
5-Hydroxytryptamine hydrogen maleate, 5-HT, 3-(2-Aminoethyl)-5-hydroxyindole hydrogen maleate
Empirical Formula (Hill Notation):
C10H12N2O · C4H4O4
CAS Number:
Molecular Weight:
292.29
Beilstein:
8173182
EC Number:
MDL number:
PubChem Substance ID:

form

powder

color

off-white to yellow

storage temp.

2-8°C

SMILES string

OC(=O)\C=C/C(O)=O.NCCc1c[nH]c2ccc(O)cc12

InChI

1S/C10H12N2O.C4H4O4/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10;5-3(6)1-2-4(7)8/h1-2,5-6,12-13H,3-4,11H2;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

LTEXAUVYLLADEB-BTJKTKAUSA-N

Gene Information

human ... HTR3A(3359)

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Biochem/physiol Actions

Neurotransmitter.

Certificate of Analysis

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Certificate of Origin

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More Documents

Quotes and Ordering

Jason Neidleman et al.
Cell reports. Medicine, 1(6), 100081-100081 (2020-08-26)
Convalescing coronavirus disease 2019 (COVID-19) patients mount robust T cell responses against SARS-CoV-2, suggesting an important role of T cells in viral clearance. To date, the phenotypes of SARS-CoV-2-specific T cells remain poorly defined. Using 38-parameter CyTOF, we phenotyped longitudinal specimens of SARS-CoV-2-specific
Jason Neidleman et al.
Cell reports, 36(3), 109414-109414 (2021-07-15)
Although T cells are likely players in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunity, little is known about the phenotypic features of SARS-CoV-2-specific T cells associated with recovery from severe coronavirus disease 2019 (COVID-19). We analyze T cells from 34 individuals with
Kerry L Price et al.
ACS chemical neuroscience, 6(7), 1151-1157 (2015-02-05)
Cys-loop receptors are the site of action of many therapeutic drugs. One of these is the smoking cessation agent varenicline, which has its major therapeutic effects at nicotinic acetylcholine (nACh) receptors but also acts at 5-HT3 receptors. Here, we report
Toko Maehara et al.
British journal of pharmacology, 172(4), 1136-1147 (2014-11-08)
Post-operative ileus (POI) is induced by intestinal inflammation. Here, we aimed to clarify the effects of 5-HT3 receptor antagonists against POI. We administered three 5-HT3 receptor antagonists, ondansetron, tropisetron and palonosetron, to a mouse model of POI induced by surgical
Nicolas Kluger et al.
Clinical immunology (Orlando, Fla.), 158(2), 212-220 (2015-03-26)
Gastrointestinal dysfunction is a disabling manifestation of APECED possibly related to an autoimmune intestinal aggression. We evaluated its features in a cohort of 31 Finnish patients. The most frequent manifestations were constipation (48%), diarrhea, dysphagia and retrosternal pain (45%). AADC

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