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D3648

Sigma-Aldrich

Diamide

Synonym(s):
N,N,N′,N′-Tetramethylazodicarboxamide, 1,1′-Azobis(N,N-dimethylformamide), Diazenedicarboxylic acid bis(N,N-dimethylamide), Azodicarboxylic acid bis(dimethylamide), TMAD
Linear Formula:
(CH3)2NCON=NCON(CH3)2
CAS Number:
Molecular Weight:
172.19
Beilstein:
1910409
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

assay

≥98% (TLC)

Quality Level

form

powder

mp

113-115 °C

solubility

water: 19.60-21.00 mg/mL, clear to slightly hazy, orange

storage temp.

−20°C

SMILES string

CN(C)C(=O)\N=N\C(=O)N(C)C

InChI

1S/C6H12N4O2/c1-9(2)5(11)7-8-6(12)10(3)4/h1-4H3/b8-7+

InChI key

VLSDXINSOMDCBK-BQYQJAHWSA-N

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Application

Reported to be of use as a thiol oxidizing agent. Diamide has been used to titrate protein glutathiolation to discriminate from other oxidative protein modifications. Treatment increased protein glutathiolation in a concentration-dependent manner and had comparably little effect on protein-protein disulfide formation.

Packaging

5 g in glass bottle

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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