All Photos(1)

68373

Sigma-Aldrich

Visfatin human, recombinant from E. coli

≥90% (GE)

NACRES:
NA.77

Quality Level

assay

≥90% (GE)

form

solid

technique(s)

western blot: suitable

impurities

≤0.1 EU/μg protein endotoxin

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... NAMPT(10135)

General description

Visfatin, also known as pre-B cell colony-enhancing factor, is a cytokine that is highly expressed in visceral fat and was originally isolated as a secreted factor that synergizes with IL-7 and stem cell factors to promote the growth of B cell precursors

Application

Western blotting

Analysis Note

Endotoxin: <0.1 EU/μg protein (LAL test)

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Certificate of Origin

Janin Berndt et al.
Diabetes, 54(10), 2911-2916 (2005-09-28)
Visceral and subcutaneous adipose tissue display important metabolic differences that underlie the association of visceral obesity with obesity-related cardiovascular and metabolic alterations. Recently, visfatin was identified as an adipokine, which is predominantly secreted from visceral adipose tissue both in humans
Miao-Pei Chen et al.
The Journal of clinical endocrinology and metabolism, 91(1), 295-299 (2005-10-20)
Visfatin (also known as pre-B cell colony-enhancing factor or PBEF) is a cytokine that is highly expressed in visceral fat and whose blood levels correlate with obesity. Originally isolated as a secreted factor that promotes the growth of B cell
Mélodie Diot et al.
Reproduction (Cambridge, England), 150(1), 53-63 (2015-04-29)
In mammals, nicotinamide phosphoribosyltransferase (NAMPT) is an adipokine produced by adipose tissue that is found in intracellular and extracellular compartments. The intracellular form of NAMPT is a nicotinamide phosphoribosyltransferase, whereas the extracellular form is considered an adipokine. In humans, NAMPT
Gong Cheng et al.
Oncology reports, 34(2), 987-994 (2015-06-13)
Visfatin is considered to be a biomarker in various types of cancers. However, no evidence has been reported for the direct effect of visfatin on osteosarcoma cell metastasis. The aims of the present study were to investigate the influence of
Xiaoqun Lv et al.
Journal of Cancer, 6(9), 849-858 (2015-08-19)
Colorectal cancer (CRC) is the third most common cancer disease. Here we examined Nampt expression in patients with CRC and the effect of Nampt on cell viability in CRC cells. Nampt protein was overexpressed in colorectal adenoma as well as

Articles

Lipid Induced Insulin Resistance

Lipid Induced Insulin Resistance

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service