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Ethylene glycol

ReagentPlus®, ≥99%

Linear Formula:
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

vapor density

2.1 (vs air)

Quality Level

vapor pressure

0.08 mmHg ( 20 °C)

product line






autoignition temp.

752 °F

expl. lim.

15.3 %

refractive index

n20/D 1.431 (lit.)


195-198 °C


−13 °C (lit.)


water: miscible


1.113 g/mL at 25 °C (lit.)

SMILES string




InChI key


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General description

Ethylene glycol (EG) is a polyol having a wide range of industrial applications. Its preparation from cellulose has been reported. It can also be produced from fossil fuels (petroleum, natural gas and coal) and biomass-derived resources.


Ethylene glycol can be used as a reagent in cyclocondensation reactions with aldehydes and ketones to form 1,3-dioxolanes.
It has been used:
  • As a carrier fluid during the fabrication of shear thickening fluid (composed of nanosized silica particles).
  • To compose previtrification and vitrification solutions for the cryopreservation of mouse embryos.


500 mL in poly bottle
1, 4 L in poly bottle
18 L in steel drum

Other Notes

The article number 102466-4X2.5L will be discontinued. Please order the single bottle 102466-2.5L which is physically identical with the same exact specifications.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the molarity of ethylene glycol?

    Ethylene glycol is 17.93M.  This is calculated using the density (1.113 g/ml) and the molecular weight (62.07 g/mol).  If the product is less than 100% pure, correct for the purity.

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Mouse embryo cryopreservation utilizing a novel high-capacity vitrification spatula.
Tsang WH and Chow KL.
Biotechniques, 46, 550-552 (2009)
Ethylene glycol: properties, synthesis, and applications.
Yue H, et al.
Chemical Society Reviews, 41(11), 4218-4244 (2012)
Tetrahedron Letters, 32, 413-413 (1991)
Study on magnetorheological shear thickening fluid.
Zhang X, et al.
Smart Materials and Structures, 17(1), 015051-015051 (2008)
Siloxanes as temporary tethers in [2+2] photocycloadditions
Crimmins MT and Guise LE
Tetrahedron Letters, 35(11), 1657-1660 (1994)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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