04276

Sodium phosphate dibasic

puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E 339, anhydrous, 98-100.5% (calc. to the dried substance)

• Synonym(s): sec-Sodium phosphate, Disodium hydrogen phosphate, Disodium phosphate, Sodium hydrogenphosphate
• Linear Formula: Na₂HPO₄
• CAS Number: 7558-79-4
• Molecular Weight: 141.96
• EC Number: 231-448-7
• MDL number: MFCD00003496
• eCl@ss: 38070211
• PubChem Substance ID: 329747909
• NACRES: NA.25

Properties

• Agency: meets analytical specifications of BP; meets analytical specifications of Ph. Eur.; meets analytical specifications of USP
• Quality Level: 200
• grade: puriss.
• assay: 98-100.5% (calc. to the dried substance)
• form: powder
• quality: meets analytical specification of Ph. Eur., BP, USP, FCC, E 339
• impurities: reducing matter, complies; residual solvents, complies; ≤0.001% heavy metals (as Pb); ≤0.002% ammonium (NH₄); ≤0.2% water-insoluble matter; ≤1% NaH₂PO₄ (calc. to dried subst.); ≤2.0% pyrophosphate (as Na₄P₂O₇)
• loss: ≤1% loss on drying, 105°C, 4h; ≤1% loss on drying, 130 °C
• pH: 8.4-9.6 (20 °C, 1%)
• pKa (25 °C): (1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid)
• solubility: H₂O: soluble 8 parts; H₂O: very soluble (Hot); alcohol: insoluble
• anion traces: chloride (Cl^-): ≤50 mg/kg; fluoride (F^-): ≤10 mg/kg; sulfate (SO₄^2-): ≤200 mg/kg
• cation traces: As: ≤2 mg/kg; Cd: ≤1 mg/kg; Cu: ≤10 mg/kg; Fe: ≤20 mg/kg; Hg: ≤1 mg/kg; Pb: ≤4 mg/kg; Zn: ≤10 mg/kg
• suitability: complies for appearance of solution
• SMILES string: [Na+].[Na+].[H]OP([O-])([O-])=O
• InChI: 1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2
• InChI key: BNIILDVGGAEEIG-UHFFFAOYSA-L

Description

Application

Sodium phosphate dibasic has been used for preparing phosphate buffer which in turn is utilized in X-gal staining.

Biochem/physiol Actions

Sodium phosphate dibasic is an important component of running buffer of denaturing gel electrophoresis. It induces glomerular calcification as well as other nephrotic syndrome in Sprague-Dawley rats.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable