PHR1124

Myristic acid

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Tetradecanoic acid, 1-Tridecanecarboxylic acid, NSC 5028, C14:0
• Linear Formula: CH₃(CH₂)₁₂COOH
• CAS Number: 544-63-8
• Molecular Weight: 228.37
• Beilstein: 508624
• EC Number: 208-875-2
• MDL number: MFCD00002744
• PubChem Substance ID: 329823145

Properties

• Quality Level: 300
• grade: certified reference material; pharmaceutical secondary standard
• Agency: traceable to USP 1448990
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• bp: 250 °C/100 mmHg (lit.)
• mp: 52-54 °C (lit.)
• application(s): cleaning products; cosmetics; food and beverages; personal care; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: CCCCCCCCCCCCCC(O)=O
• InChI: 1S/C14H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h2-13H2,1H3,(H,15,16)
• InChI key: TUNFSRHWOTWDNC-UHFFFAOYSA-N

Description

General description

Myristic acid is a saturated fatty acid, which can increase the low-density lipoprotein cholesterol level and its sources are found to be coconut oil, palm kernal oil, butter fat and nutmeg.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease .

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA7148 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable