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P6585

Sigma-Aldrich

TWEEN® 20

Low-peroxide; Low-carbonyls

Synonym(s):
Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate
CAS Number:
MDL number:
NACRES:
NA.21

Quality Level

description

non-ionic

form

viscous liquid

mol wt

~1228

contains

BHT as antioxidant

impurities

≤0.5 μmol/g Peroxides
≤1.0 μmol/g Carbonyls
≤3.0% water

refractive index

n20/D 1.468 (lit.)

CMC

0.06 mM (20-25°C)

transition temp

cloud point 76 °C

density

1.095 g/mL at 25 °C (lit.)
1.1 g/cm3 at 25 °C (lit.)

HLB

16.7

storage temp.

2-8°C

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

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General description

Tween®20 is a polyoxyethylene sorbitol ester that belongs to the polysorbate family. It is a nonionic detergent having a molecular weight of 1,225 daltons, assuming 20 ethylene oxide units, 1 sorbitol, and 1 lauric acid as the primary fatty acid. The ethylene oxide subunits are responsible for the hydrophilic nature of the surfactant, while the hydrocarbon chains provide the hydrophobic environment. Sorbitol forms the backbone ring to which the ethylene oxide polymers are attached.

Application

Tween 20 has been used along with PBS to wash plates in ELISA technique.
Non-ionic detergent

Packaging

10, 100 mL in glass bottle

Preparation Note

Purified to remove peroxides and aldehydes

Legal Information

TWEEN is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

527.0 °F - Pensky-Martens closed cup

Flash Point(C)

275 °C - Pensky-Martens closed cup

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Poke but don't pinch: risk assessment and venom metering in the western black widow spider, Latrodectus hesperus.
Nelsen DR
Animal behaviour, 89, 107-114 (2014)
Galit Katarivas Levy et al.
Journal of clinical medicine, 8(10) (2019-09-25)
There is currently an interest in "active" implantable biomedical devices that include mechanical stimulation as an integral part of their design. This paper reports the experimental use of a porous scaffold made of interconnected networks of slender ferromagnetic fibers that...
Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: structure and degradation pathways.
Kerwin BA
Journal of Pharmaceutical Sciences, 97(8), 2924-2935 (2008)
P Lewis White et al.
Journal of clinical microbiology, 49(6), 2169-2174 (2011-04-01)
Diagnosis of invasive aspergillosis remains a significant problem. PCR testing may aid diagnosis but is not yet included in disease-defining criteria due to a lack of standardization of assays and methodologies. This study investigated the analytical performance and the clinical...
Louis Hermo et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 56(12), 1121-1135 (2008-09-18)
Water content within the epididymis of the male reproductive system is stringently regulated to promote sperm maturation. Several members of the aquaporin (AQP) family of water channel-forming integral membrane proteins have been identified in epididymal cells, but expression profiling for...

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