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Gallic acid

certified reference material, TraceCERT®

3,4,5-Trihydroxybenzoic acid
Linear Formula:
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


certified reference material

product line


shelf life

limited shelf life, expiry date on the label

storage condition

under inert gas (Argon)


HPLC: suitable
gas chromatography (GC): suitable


251 °C (dec.) (lit.)


cleaning products
flavors and fragrances
food and beverages
personal care



shipped in

wet ice

storage temp.


SMILES string




InChI key


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General description

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at:


Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Gallic acid has been used as a reference standard in the high performance liquid chromatography coupled triple quadrupole mass spectrometric (HPLC/QqQ MS) analysis of gallic acid in rat medicated plural serum containing Guizhi Fuling Wan, a chinese herbal formula used for the treatment of ovarian cancer.

Biochem/physiol Actions

Gallic acid is a water soluble phenolic acid present in grapes and in the leaves of many plants. Gallic acid esters, such as tannins, catechin gallates and aliphatic gallates are potent antioxidants in vitro. However, gallic acid itself also appears to have antioxidant, anticarcinogenic and antiangiogenic activity in vitro.


Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

TraceCERT is a registered trademark of Sigma-Aldrich Co. LLC


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Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

More documents

Quotes and Ordering

S Shahrzad et al.
The Journal of nutrition, 131(4), 1207-1210 (2001-04-04)
Gallic acid (GA), a food component that is especially abundant in tea, is an antimutagenic, anticarcinogenic and anti-inflammatory agent. We conducted a study using acidum gallicum tablets that contained 10% GA and 90% glucose and a black tea brew that
Guizhi fuling wan, a traditional chinese herbal formula, sensitizes cisplatin-resistant human ovarian cancer cells through inactivation of the PI3K/AKT/mTOR pathway
Han L, et al.
Evidence-Based Complementary and Alternative Medicine : ECAM (2016)
T R Aguiar et al.
Journal of dental research, 93(4), 417-422 (2014-02-28)
Although proanthocyanidins (PACs) modify dentin, the effectiveness of different PAC sources and the correlation with their specific chemical composition are still unknown. This study describes the chemical profiling of natural PAC-rich extracts from 7 plants using ultra high pressure/performance liquid
Plant polyphenols (vegetable tannins): gallic acid metabolism.
E Haslam et al.
Natural product reports, 11(1), 41-66 (1994-01-01)
Yanqin Liu et al.
Biochimica et biophysica acta, 1844(9), 1481-1485 (2014-04-29)
The accumulation of protein aggregates containing amyloid fibrils, with α-synuclein being the main component, is a pathological hallmark of Parkinson's disease (PD). Molecules which prevent the formation of amyloid fibrils or disassociate the toxic aggregates are touted as promising strategies


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