85431

Supelco

Silylating mixture I according to Sweeley

for GC derivatization, LiChropur

Synonym(s):
hexamethyldisilazane/chlorotrimethylsilane/pyridine = 2:1:10 (v/v/v), HMDS + TMCS, Sylon HTP, Chlorotrimethylsilane – hexamethyldisilazane mixture
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

grade

for GC derivatization

description

ready to use solution in pyridine (10 vol parts)

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

application(s)

gas chromatography (GC): suitable

storage temp.

2-8°C

SMILES string

C[Si](C)(C)Cl.C[Si](C)(C)N[Si](C)(C)C.C[Si](C)(C)N[Si](C)(C)C

InChI

1S/2C6H19NSi2.C3H9ClSi/c2*1-8(2,3)7-9(4,5)6;1-5(2,3)4/h2*7H,1-6H3;1-3H3

InChI key

UCJNZOHHMSKSRP-UHFFFAOYSA-N

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Application

Learn more in the Product Information

Components

hexamethyldisilazane : chlorotrimethylsilane : pyridine = 2:1:10 (v/v)

Other Notes

Useful silylating mixture for the silylation of hydroxy-compounds

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
Sylon is a trademark of Sigma-Aldrich Co. LLC

Signal Word

Danger

hazcat

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

storage_class_code

3 - Flammable liquids

WGK Germany

WGK 2

Flash Point(F)

68.0 °F - closed cup

Flash Point(C)

20 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

J. Heberle et al.
Silylating Agents, 2nd ed. (1995)
Sweeley, C.C., et al.
Journal of the American Chemical Society, 85, 2497-2497 (1963)
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