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Supelco

Homovanillic acid

analytical standard

Synonym(s):

4-Hydroxy-3-methoxyphenylacetic acid, HVA

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About This Item

Linear Formula:
HOC6H3(OCH3)CH2CO2H
CAS Number:
306-08-1
Molecular Weight:
182.17
Beilstein/REAXYS Number:
2213447
EC Number:
206-176-7
MDL number:
MFCD00004350
UNSPSC Code:
77101502
PubChem Substance ID:
329761856
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥97.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

142-145 °C (lit.)
142-145 °C

application(s)

pharmaceutical

format

neat

SMILES string

COc1cc(CC(O)=O)ccc1O

InChI

1S/C9H10O4/c1-13-8-4-6(5-9(11)12)2-3-7(8)10/h2-4,10H,5H2,1H3,(H,11,12)

InChI key

QRMZSPFSDQBLIX-UHFFFAOYSA-N

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Application

Homovanillic acid may be used as a reference standard in the determination of homovanillic acid in samples of human cerebrospinal fluid using gas chromatography coupled with electron capture detector.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG8919
BCCG2774
BCCG0154
BCCD8758
BCCC5315

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On the occurrence of homovanillic acid in brain and cerebrospinal fluid and its determination by a fluorometric method.
Sjoquist B and Anggard E.
Life Sciences, 2(7), 448-458 (1963)
Kyung Tai Lee et al.
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Michael Schwarzer et al.
The Journal of physiology, 592(17), 3767-3782 (2014-06-22)
We investigated the impact of cardiac reactive oxygen species (ROS) during the development of pressure overload-induced heart failure. We used our previously described rat model where transverse aortic constriction (TAC) induces compensated hypertrophy after 2 weeks, heart failure with preserved
M A Aguilar et al.
Brain research bulletin, 113, 27-33 (2015-03-01)
Although the consumption of cocaine is frequent in young users of MDMA (3,4-methylenedioxymethamphetamine), the influence of exposure to cocaine on the rewarding effects of MDMA in adolescents has not been studied. The purpose of the present work was to evaluate
Sandy Stayte et al.
PloS one, 10(4), e0124325-e0124325 (2015-04-23)
Parkinson's disease (PD) is a chronic neurodegenerative disease characterized by a significant loss of dopaminergic neurons within the substantia nigra pars compacta (SNpc) and a subsequent loss of dopamine (DA) within the striatum. Despite advances in the development of pharmacological
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