All Photos(1)

15716

Supelco

Boron trifluoride-methanol solution

~10% (~1.3 M), for GC derivatization, LiChropur

Linear Formula:
BF3 · MeOH
CAS Number:
Molecular Weight:
99.85
Beilstein:
3611499
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.05

Quality Level

grade

for GC derivatization

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Esterifications

concentration

~10% (~1.3 M)

application(s)

gas chromatography (GC): suitable

density

0.86 g/mL at 20 °C

storage temp.

2-8°C

SMILES string

CO.FB(F)F

InChI

1S/CH4O.BF3/c1-2;2-1(3)4/h2H,1H3;

InChI key

JBXYCUKPDAAYAS-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Boron trifluoride (BF3) is a Lewis acid; it is a very useful reagent for forming esters from acids. Boron trifluoride is commercially available as a 14% solution in methanol for forming esters derivatives. It catalysed reactions carried out in a water bath are very rapid and can be completed in a few minutes. Boron-trifluoride-catalysed transesterification of vegetable oils is one of the most popular methods. For transesterification of vegetable oils, BF3 is used in methanol (15 to 20% w/v).

Application

Boron trifluoride-methanol solution may be used for catalysing a method, used for the synthesis of bishydroperoxides and their derivatives, based on a reaction of ketals with a solution of hydrogen peroxide in anhydrous ether. It may also be used for the rapid preparation of fatty acid esters for gas chromatographic analysis, as it converts fatty acids to their respective methyl esters in about 2 minutes.
Learn more in the Product Information
Suitable for derivatization of hydroxy fatty acids.

Other Notes

Reagent for methyl ester, O-acetyl.
Reagent for esterifying fatty acid for gas chromatographic analysis

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 1

Storage Class Code

3 - Flammable liquids

WGK Germany

WGK 2

Flash Point(F)

49.5 °F

Flash Point(C)

9.7 °C

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

The rapid preparation of fatty acid esters for gas chromatographic analysis.
Metcalfe LD and Schmitz AA.
Analytical Chemistry, 33 (3), 363-364 (1961)
Christian F Ruiz et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(8), 10574-10589 (2020-06-23)
Cancer cells require extensive metabolic reprograming in order to provide the bioenergetics and macromolecular precursors needed to sustain a malignant phenotype. Mutant KRAS is a driver oncogene that is well-known for its ability to regulate the ERK and PI3K signaling...
H. Rotzsche
Journal of Chromatography A, 552, 281-281 (1991)
Introduction to Analytical Gas Chromatography, 219-219 (1997)
Biodiesel: A Realistic Fuel Alternative for Diesel Engines.
Demirbas A.
Technology & Engineering, 123-124 (2007)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service