ABN343
Anti-NIPSNAP Antibody
from rabbit, purified by affinity chromatography
Synonym(s):
Non-neuronal SNAP25-like protein, NIPSNAP1, NIPSNAP
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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General description
NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP’s expression is reduced in the phenylketonuria (PKU) brain, suggesting that NIPSNAP may play a role in memory.
Immunogen
KLH-conjugated linear peptide corresponding to human NIPSNAP.
Application
Detect the NIPSNAP protein using this Anti-NIPSNAP validated for use in WB & IHC.
Immunohistochemistry Analysis: 2.5 µg/mL of this antibody from a representative lot detected NIPSNAP in human brain tissue.
Quality
Evaluated by Western Blot in human brain tissue lysate.
Western Bloting Analysis: 1 µg/mL of this antibody detected NIPSNAP in 15 µg of human brain tissue lysate.
Western Bloting Analysis: 1 µg/mL of this antibody detected NIPSNAP in 15 µg of human brain tissue lysate.
Target description
~33 kDa observed
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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