1.37046

Sodium acetate

anhydrous, EMPROVE^® EXPERT, USP

• Synonym(s): Acetic acid sodium salt, Sodium acetate
• Linear Formula: CH₃COONa
• CAS Number: 127-09-3
• Molecular Weight: 82.03
• Beilstein: 3595639
• MDL number: MFCD00012459
• EC Index Number: 204-823-8

Properties

• Quality Level: 500
• Agency: USP
• product line: EMPROVE^® EXPERT
• form: solid
• autoignition temp.: 1112 °F; 607 °C
• pH: 7.5-9.2 (20 °C, 30 g/L in H₂O)
• pKa: 4.76 (acetic acid)
• bp: >400 °C (decomposition)
• mp: >300 °C (dec.) (lit.); 324 °C (decomposition)
• transition temp: flash point >250 °C
• solubility: 365 g/L
• density: 1.52 g/cm³ at 20 °C
• application(s): biopharma process and formulation; liquid formulation; parenterals; pharmaceutical
• storage temp.: 15-25°C
• SMILES string: [Na+].CC([O-])=O
• InChI: 1S/C2H4O2.Na/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1
• InChI key: VMHLLURERBWHNL-UHFFFAOYSA-M

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium acetate anhydrous is an acetate buffer system component commonly used in downstream biomolecule chromatography steps as well as liquid formulation.
Due to its low microbial and endotoxin limits, Sodium acetate anhydrous Emprove^® Expert is especially suitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1