reag. Ph. Eur.
1.41 (vs air)
72.8 mmHg ( 20 °C)
97 hPa ( 20 °C)
≤0.0002 meq/g Acidity
≤0.0002 meq/g Alkalinity
193 nm, ≥60%
195 nm, ≥80%
230 nm, ≥98%
n20/D 1.344 (lit.)
81-82 °C (lit.)
−45 °C (lit.)
flash point 2 °C
0.786 g/mL at 25 °C (lit.)
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Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
3 - Flammable liquids
35.6 °F - closed cup
2.0 °C - closed cup
Apixaban is sold under the tradename Eliquis and at present no pharmacopeial monographs are available for Axpixaban using either an assay and/or organic impurity profiling method. A newly developed and validated HPLC-UV method using a column with C18 solid core particles is demonstrated.
The most frequently used synthetic sweeteners are: saccharin, cyclamate, aspartame, and sucralose (E955), and this application illustrate the analysis of sucralose from soy sauce following the current Chinese national standard method.
Following the new USP monograph for Famciclovir Tablets, Purospher™ STAR RP-8 endcapped HPLC columns can be used to monitor organic impurities in Famciclovir tablet formulations. Famciclovir is an antiviral drug indicated for the treatment of herpes zoster, herpes simplex virus 2 (genital herpes), herpes labialis (cold sores), etc.
Separation of p-Toluenesulfonic acid (PTSA); Pyrimethamine
HPTLC was used to analyze caffeine in coffee. Filtration of coffee through a PTFE syringe filter was the only sample preparation. Quantitation was conducted with a TLC scanner.
Sildenafil Citrate Method (HPLC) following USP Monograph on Ascentis Express C18 with UV detection
Praziquantel Determination in Aquarium Water- Learn how the use of a Chromolith® monolithic silica column allows simplification of sample preparation.
A rapid, accurate, and simple method was implemented for the total chromatographic purity analysis of Fingolimod Hydrochloride by High-Performance Liquid Chromatography equipped with a Diode Array Detector.