MilliporeSigma
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745405

Sigma-Aldrich

Sodium 1,1-difluoroethanesulfinate

Synonym(s):
Baran DFES Reagent, DFES-Na Reagent, Baran Difluoroethylation Reagent, Sodium 1,1-difluoroethylsulfinate
Empirical Formula (Hill Notation):
C2H3F2NaO2S
CAS Number:
Molecular Weight:
152.10
MDL number:
PubChem Substance ID:

Quality Level

form

solid

reaction suitability

reaction type: C-C Bond Formation
reaction type: Fluorinations
reagent type: catalyst
reaction type: C-H Activation

reagent type: diversification reagent

mp

>300 °C

SMILES string

[Na+].CC(F)(F)S([O-])=O

InChI

1S/C2H4F2O2S.Na/c1-2(3,4)7(5)6;/h1H3,(H,5,6);/q;+1/p-1

InChI key

YAUVUSSCQUHHFC-UHFFFAOYSA-M

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Application

DFES-Na provides a direct approach to fluorinated heteroarylether bioisosteres by appending a 1,1-difluoroethyl group operationally simple and robust protocol. This reagent was developed by the Baran Group and is one of several reagents for the direct alkylation of heterocycles.

Learn More at the Professor and Product Portal of Professor Phil S. Baran.
Baran Diversinates(TM) Lead Diversification and Metabolism Prediction Flyer

Packaging

1, 10 g in poly bottle

Linkage

Frequently Asked Questions are available for this Product.

Other Notes

Previously sold under product number L511404

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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Articles

Baran Diversinates™

The synthesis of heteroaromatic and aromatic compounds is at the heart of the chemical industry. The ever-growing demand for new chemical entities, coupled with dwindling resources and time constraints allotted to any given research project, a rapid way to diversify (hetero)aromatic scaffolds is needed.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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