MilliporeSigma
All Photos(1)

568864

Sigma-Aldrich

Fluorescein O-methacrylate

95%

Synonym(s):
3′-Methacryloxyspirobenzo[c]-furan[1,9’]xanthen-3-one, Methacryloyloxy fluorescein
Empirical Formula (Hill Notation):
C24H16O6
CAS Number:
Molecular Weight:
400.38
MDL number:
PubChem Substance ID:
NACRES:
NA.23

Quality Level

assay

95%

form

solid

mp

227-232 °C (lit.)

λmax

490 nm

storage temp.

2-8°C

SMILES string

CC(=C)C(=O)Oc1ccc2c(Oc3cc(O)ccc3C24OC(=O)c5ccccc45)c1

InChI

1S/C24H16O6/c1-13(2)22(26)28-15-8-10-19-21(12-15)29-20-11-14(25)7-9-18(20)24(19)17-6-4-3-5-16(17)23(27)30-24/h3-12,25H,1H2,2H3

InChI key

YMHPNLUYVDEYCI-UHFFFAOYSA-N

General description

Fluorescein O-methacrylate is a pH sensitive dye with a fluorescent monomer. It can be characterized by an excitation spectra at 490 nm and an emission spectra at 520 nm. It has fluorescein that acts as an indicator with the least negative charges. Its properties include biocompatibility, non-toxicity and good dispersion in aqueous solution.

Application

Fluorescein O-methacrylate can be used as a marker that can be incorporated into the nanoparticle complexes for biological applications. It forms environmentally responsive materials that can be used as probes for cellular imaging.
Fluorescent monomer

Packaging

1 g in glass bottle
500 mg in glass insert

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Zhenhua Li et al.
Nanoscale, 9(40), 15407-15415 (2017-10-05)
Protein modified functional surfaces have been applied extensively in the field of biomaterials and medicine. Regulation of the amount and activity of proteins on the material surface is always a challenge and a key research issue. A multifunctional micro/nano-composite based
Synthesis and characterization of multifunctional Fe3O4/poly (fluorescein O-methacrylate) core/shell nanoparticles
Govindaiah P, et al.
Journal of Colloid and Interface Science, 379(1), 27-32 (2012)
Disposable fluorescence optical pH sensor for near neutral solutions
Ferrari L, et al.
Sensors, 13(1), 484-499 (2013)
Fanny Joubert et al.
Materials (Basel, Switzerland), 12(17) (2019-08-28)
We compared the influence of the polymerization mechanism onto the physical characteristics of thermoresponsive hydrogels. The Poly(N-isopropylacrylamide) (PNIPAAm) hydrogels were successfully synthesized using reversible addition-fragmentation chain-transfer (RAFT) and free radical polymerization (FRP). The gels were prepared while using different crosslinker
Aydan Dag et al.
Biomacromolecules, 20(8), 2962-2972 (2019-07-18)
An important requirement to decrease the side effects of chemotherapy drugs is to develop nanocarriers with precise biological functions. In this work, a set of glyconanoparticles was prepared via self-assembly of amphiphilic glycoblock copolymers for the targeted delivery of a

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service